Abstract
Purpose
Refractory urinary incontinence after channel transurethral resection of the prostate (cTURP) (TURP in the setting of prostate cancer) is a rare occurrence treated with artificial urinary sphincter (AUS). We sought to characterize those patients receiving AUS after cTURP and understand device longevity.
Materials and methods
We identified patients who underwent cTURP and AUS placement in SEER-Medicare from 2002 to 2014. We analyzed factors affecting device longevity using multivariable Cox proportional hazard models. We performed propensity matching to accurately compare patients receiving AUS after cTURP to those receiving AUS after radical prostatectomy (RP).
Results
For patients undergoing cTURP, 201 out of 56,957 ultimately underwent AUS placement (< 0.5%). AUS after cTURP incurred a 48.4% rate of reoperation versus 30.9% after RP. Importantly, patients undergoing cTURP were significantly older than those undergoing RP [75 vs. 71 years of age (p < 0.01)]. At 3 years after insertion, 28.2% of patients after RP required reoperation compared to 37.8% of patients post-cTURP (p < 0.01). There were no detectable differences in revision rates for those patients who underwent traditional vs. laser cTURP. Patients with a history of radiation therapy had significantly shorter device survival. Even after propensity matching, patients receiving AUS after cTURP incurred more short-term complications compared to AUS after RP. Differences in device longevity were diminished after propensity match.
Conclusions
In the SEER-Medicare population, AUS after cTURP remains rare. While there is an increased risk of infectious complications, AUS after cTURP fared similarly to AUS after RP in terms of device longevity. A history of radiation therapy leads to worse outcome for all patients.
Similar content being viewed by others
References
Gratzke C et al (2015) EAU Guidelines on the assessment of non-neurogenic male lower urinary tract symptoms including benign prostatic obstruction. Eur Urol 67(6):1099–1109
Ficarra V et al (2012) Systematic review and meta-analysis of studies reporting urinary continence recovery after robot-assisted radical prostatectomy. Eur Urol 62(3):405–417
Theodorou C, Moutzouris G, Floratos D, Plastiras D, Katsifotis C, Mertziotis N (1998) Incontinence after surgery for benign prostatic hypertrophy: the case for complex approach and treatment. Eur Urol 33(4):370–375
Rassweiler J, Teber D, Kuntz R, Hofmann R (2006) Complications of transurethral resection of the prostate (TURP)—incidence, management, and prevention. Eur Urol 50(5):969–980
Pickard R (2007) Male incontinence: pathophysiology and management. Indian J Urol IJU 23(2):179–180
Mazur AW, Thompson IM (1991) Efficacy and morbidity of ‘channel’ TURP. Urology 38(6):526–528
Heesakkers J, Farag F, Bauer RM, Sandhu J, De Ridder D, Stenzl A (2017) Pathophysiology and contributing factors in postprostatectomy incontinence: a review. Eur Urol 71(6):936–944
Friedl A et al (2017) The adjustable transobturator male system in stress urinary incontinence after transurethral resection of the prostate. Urology 109:184–189
Kretschmer A et al (2016) Long-term outcome of the retrourethral transobturator male sling after transurethral resection of the prostate. Int Neurourol J 20(4):335–341
Hogewoning CRC, Meij LAM, Pelger RCM, Putter H, Krouwel EM, Elzevier HW (2017) Sling surgery for the treatment of urinary incontinence after transurethral resection of the prostate: new data on the virtue male sling and an evaluation of literature. Urology 100:187–192
Yafi FA, Powers MK, Zurawin J, Hellstrom WJG (2016) Contemporary review of artificial urinary sphincters for male stress urinary incontinence. Sex Med Rev 4(2):157–166
Gundian JC, Barrett DM, Parulkar BG (1993) Mayo Clinic experience with the AS800 artificial urinary sphincter for urinary incontinence after transurethral resection of prostate or open prostatectomy. Urology 41(4):318–321
Cohen AJ, Kuchta K, Park S, Milose J (2018) Patterns and timing of artificial urinary sphincter failure. World J Urol 36:939–945
Klabunde CN, Potosky AL, Legler JM, Warren JL (2000) Development of a comorbidity index using physician claims data. J Clin Epidemiol 53(12):1258–1267
Kuntz RM, Ahyai S, Lehrich K, Fayad A (2004) Transurethral holmium laser enucleation of the prostate versus transurethral electrocautery resection of the prostate: a randomized prospective trial in 200 patients. J Urol 172(3):1012–1016
Bachmann A et al (2015) A European multicenter randomized noninferiority trial comparing 180 W GreenLight XPS laser vaporization and transurethral resection of the prostate for the treatment of benign prostatic obstruction: 12-month results of the goliath study. J Urol 193(2):570–578
Bruschini H, Simonetti R, Antunes AA, Srougi M (2011) Urinary incontinence following surgery for BPH: the role of aging on the incidence of bladder dysfunction. Int Braz J Urol 37(3):380–386 (discussion 387)
Punnen S, Cowan JE, Chan JM, Carroll PR, Cooperberg MR (2015) Long-term health-related quality of life after primary treatment for localized prostate cancer: results from the CaPSURE registry. Eur Urol 68(4):600–608
Kopp RP et al (2013) The burden of urinary incontinence and urinary bother among elderly prostate cancer survivors. Eur Urol 64(4):672–679
Viers BR, Linder BJ, Rivera ME, Rangel LJ, Ziegelmann MJ, Elliott DS (2016) Long-term quality of life and functional outcomes among primary and secondary artificial urinary sphincter implantations in men with stress urinary incontinence. J Urol 196(3):838–843
Polland A et al (2017) Preoperative symptoms predict continence after post-radiation transurethral resection of prostate. Can J Urol 24(4):8903–8909
Viers BR et al (2016) The impact of diabetes mellitus and obesity on artificial urinary sphincter outcomes in men. Urology 98:176–182
Kaufman MR et al (2017) Prior radiation therapy decreases time to idiopathic erosion of artificial urinary sphincter: a multi-institutional analysis. J Urol 199:1037–1041
Zlotta AR, Giannakopoulos X, Maehlum O, Ostrem T, Schulman CC (2003) Long-term evaluation of transurethral needle ablation of the prostate (TUNA) for treatment of symptomatic benign prostatic hyperplasia: clinical outcome up to 5 years from three centers. Eur Urol 44(1):89–93
Onyeji IC et al (2017) Impact of surgeon case volume on reoperation rates after inflatable penile prosthesis surgery. J Urol 197(1):223–229
Wilson SK, Zumbe J, Henry GD, Salem EA, Delk JR, Cleves MA (2007) Infection reduction using antibiotic-coated inflatable penile prosthesis. Urology 70(2):337–340
Simhan J et al (2015) 3.5 cm artificial urinary sphincter cuff erosion occurs predominantly in irradiated patients. J Urol 193(2):593–597
Suskind AM, Walter LC, Zhao S, Finlayson E (2017) Functional outcomes after transurethral resection of the prostate in nursing home residents. J Am Geriatr Soc 65(4):699–703
Gilling P, Anderson P, Tan A (2017) Aquablation of the prostate for symptomatic benign prostatic hyperplasia: 1-year results. J Urol 197(6):1565–1572
Umari P et al (2017) Robotic assisted simple prostatectomy versus holmium laser enucleation of the prostate for lower urinary tract symptoms in patients with large volume prostate: a comparative analysis from a high volume center. J Urol 197(4):1108–1114
Author information
Authors and Affiliations
Contributions
JM had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. JM, AC and SF: protocol/project development. KK: data collection or management. KK, AC, JM and WB: data analysis. All authors were involved in drafting and critical revision of the manuscript. KK and others: statistical analysis.
Corresponding author
Ethics declarations
Conflict of interest
All authors have no disclosure of potential conflicts of interest.
Ethical statements
This research was given IRB exemption and received additional SEER-Medicare exemption, as anonymous data were used.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Electronic supplementary material
Below is the link to the electronic supplementary material.
Rights and permissions
About this article
Cite this article
Cohen, A.J., Boysen, W., Kuchta, K. et al. Artificial urinary sphincter longevity following transurethral resection of the prostate in the setting of prostate cancer. World J Urol 37, 2755–2761 (2019). https://doi.org/10.1007/s00345-019-02684-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00345-019-02684-z