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Nocturia and its impact on health-related quality of life and health care seeking behaviour in German community-dwelling men aged 50 years or older

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Abstract

Purpose

To evaluate the prevalence of nocturia/nocturnal voiding frequency and its impact on overall physical and mental health status in German community-dwelling men and determine which lower urinary tract symptom (LUTS) is responsible for medical consultations in the 2-year follow-up period.

Methods

A sample of German men aged 50–80 years from a community-dwelling study was chosen for re-evaluation 2 years after initial assessment. Men were clinically investigated and completed the International Prostate Symptom Score, American Urology Association-Symptom Problem Index (AUA-SPI), and the Short-Form Health Survey (SF-12).

Results

In total, 1,562 men were eligible for analysis. Mean nocturnal voiding frequency was 2.3 for all men and increased with ageing. SF-12 data indicated that physical but not mental health status was lower than in the average population. LUTS severity reduced both physical and mental health status (p < 0.001). Clinically relevant nocturia (≥2 voids/night) was present in 43 % of men and reduced both physical and mental health status (p < 0.001), whereas both HRQoL scales were not significantly reduced in men without or only one nocturnal void. In multivariate regression analysis using patient-reported bother (AUA-SPI) from LUTS, only bother from nocturnal voiding was significantly associated with medical consultations in the investigated 2-year follow-up period (odds ratio 2.6; 95 % confidence interval 1.6–4.2; p < 0.001).

Conclusions

Our study confirmed that nocturnal voiding is highly prevalent in community-dwelling men and reduce both physical and mental health status. Bother from nocturnal voiding is the most relevant component of LUTS responsible for medical consultations in German men.

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Acknowledgments

The authors thank the German Working Group on BPH of the German Society of Urology for sponsoring the study from 1999 to 2005. The analyses shown in this article originate from data obtained in the follow-up visits of the original study.

Conflict of interest

Matthias Oelke is a consultant, speaker, and/or trial investigator in the field of LUTS/BPH for Apogepha, Astellas, Ferring, GlaxoSmithKline, Lilly, Mundipharma, Pfizer, and Recordati. Birgitt Wiese has no conflicts of interests. Richard Berges is consultant, speaker, and/or trial investigator in the field of LUTS/BPH for Astellas, Ferring, GlaxoSmithKline, Lilly, Pfizer, and Recordati.

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Authors and Affiliations

  1. Department of Urology, OE 6240, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany

    Matthias Oelke

  2. Department of Medical Statistics, IT-Infrastructure Institute of General Practice, Hannover Medical School, Hannover, Germany

    Birgitt Wiese

  3. Department of Urology, PAN-Klinik, Cologne, Germany

    Richard Berges

Authors
  1. Matthias Oelke
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  2. Birgitt Wiese
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  3. Richard Berges
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Correspondence to Matthias Oelke.

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Oelke, M., Wiese, B. & Berges, R. Nocturia and its impact on health-related quality of life and health care seeking behaviour in German community-dwelling men aged 50 years or older. World J Urol 32, 1155–1162 (2014). https://doi.org/10.1007/s00345-014-1374-6

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  • DOI: https://doi.org/10.1007/s00345-014-1374-6

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