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Comparison of the human with the sheep genomes by use of human chromosome-specific painting probes

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Abstract.

Human chromosome specific painting probes were hybridized on sheep (Ovis aries, 2n = 54) chromosomes by FISH. The painting results on sequentially stained RBA-banded preparations demonstrated high degree of conserved regions between human and sheep genomes. A total of 48 human chromosome segments were detected in sheep chromosomes. Comparisons with sheep gene mapping data available and previous Zoo-FISH data obtained in sheep, cattle, and river buffalo were performed.

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Received: 13 October 1998 / Accepted: 18 February 1999

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Iannuzzi, L., Di Meo, G., Perucatti, A. et al. Comparison of the human with the sheep genomes by use of human chromosome-specific painting probes. 10, 719–723 (1999). https://doi.org/10.1007/s003359901078

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  • DOI: https://doi.org/10.1007/s003359901078

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