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Technical safety and efficacy of a blunt-tip microwave ablation electrode for CT-guided ablation of pulmonary ground-glass opacity nodules

  • Interventional
  • Published:
European Radiology Aims and scope Submit manuscript

Abstract

Objectives

To evaluate the safety and technical efficacy of a customized blunt-tip microwave ablation (MWA) electrode for CT-guided ablation of pulmonary ground-glass opacity nodules (GGOs).

Materials and methods

This was a retrospective before-after study. All consented patients with GGOs who underwent MWA treatment using conventional sharp-tip electrodes (group A) between January 2018 and December 2018 or new blunt-tip electrodes (group B) between January 2019 and December 2019 in our institution were included. The individual features of each patient and lesion, as well as technical and clinical information, were collected and analyzed.

Results

Sixteen (7 males, 9 females; mean age, 64.9 ± 12.3 years) and twenty-six (11 males, 15 females; mean age, 66.5 ± 10.7 years) patients were enrolled in groups A and B, respectively. The technique was successfully performed in all patients and a follow-up CT scan at 24 h after MWA showed that the technical efficacy rate was 100% in both groups. Twelve (75.0%) grade I complications were noted in group A, whereas 11 (42.3%) were noted in group B (p = 0.039, chi-square test). No bleeding occurred within the lesions in group B.

Conclusions

The blunt-tip MWA electrode is a safe and technically effective tool for ablating GGO lesions.

Key Points

• A new blunt-tip MWA electrode was used for CT-guided ablation of GGO lesions.

• The blunt-tip MWA electrode could improve the safety of GGO ablation.

• The technical efficacy of ablation was maintained by using the blunt-tip MWA electrode.

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Abbreviations

AAH:

Atypical adenomatous hyperplasia

AIS:

Adenocarcinoma in situ

GGO:

Ground-glass opacity

IA:

Invasive adenocarcinomas

MIA:

Minimally invasive adenocarcinomas

MWA:

Microwave ablation

RFA:

Radiofrequency ablation

SD:

Standard deviation

SIR:

Society of Interventional Radiology

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Acknowledgements

Jiachang Chi and Zhi Wang collected the data of the patients, designed the pipeline of the analysis, and drafted the manuscript. Bo Zhai conceived and coordinated the overall study and revised the manuscript. All authors read and approved the final manuscript.

Funding

This study was supported by the Innovation Funding of Renji Hospital (No. PY2018-III-11).

Author information

Author notes

  1. Jiachang Chi and Zhi Wang contributed equally to this work.

Authors and Affiliations

  1. Department of Interventional Oncology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, 160# Pujian Road, Shanghai, 200127, China

    Jiachang Chi, Zhi Wang, Min Ding, Hao Hu & Bo Zhai

Authors
  1. Jiachang Chi
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  2. Zhi Wang
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  3. Min Ding
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  4. Hao Hu
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  5. Bo Zhai
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Corresponding authors

Correspondence to Jiachang Chi or Bo Zhai.

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Guarantor

The scientific guarantor of this publication is Bo Zhai.

Conflict of interest

The authors of this manuscript declare no relationships with any companies whose products or services may be related to the subject matter of the article.

Statistics and biometry

One of the authors, Min Ding, has significant statistical expertise.

Informed consent

Written informed consent was obtained from all subjects (patients) in this study.

Ethical approval

Institutional Review Board approval was obtained.

Methodology

• Retrospective

• Case-control study

• Performed at one institution

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Cite this article

Chi, J., Wang, Z., Ding, M. et al. Technical safety and efficacy of a blunt-tip microwave ablation electrode for CT-guided ablation of pulmonary ground-glass opacity nodules. Eur Radiol 31, 7484–7490 (2021). https://doi.org/10.1007/s00330-021-07774-4

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  • DOI: https://doi.org/10.1007/s00330-021-07774-4

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