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Large nearly spherical ablation zones are achieved with simultaneous multi-antenna microwave ablation applied to treat liver tumours

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Abstract

Aim

To investigate the shape and the volume of ablation zones obtained with microwave ablation (MWA) performed with multiple antennas in liver tumours.

Materials and methods

Tumour volume, number of antennas, size (long diameter (Dl), along the antenna axis; short diameter (Ds), perpendicular to the antenna axis; vertical diameter (Dv), vertical to both Dl and Ds) and shape (roundness index (RI); 1 corresponds to a sphere) of the ablation zone, ablation volume, and complications were evaluated.

Results

Mean Dl, Ds, and Dv were 4.7 ± 1.4 cm, 3.9 ± 1.4 cm, and 3.8 ± 1.0 cm, respectively. Mean RIs (Ds/Dl, Dv/Dl, and Dv/Ds) were 0.83 ± 0.13, 0.83 ± 0.17, and 1.02 ± 0.23, respectively, without any difference between the mean RI obtained with the double (0.84 ± 0.01) and that with the triple-antenna (0.93 ± 0.13) approach (p = 0.25). Mean ablation volume was 41 ± 32 cm3 (vs. mean tumour volume 13 ± 10 cm3; range 1–40; p < 0.001). No complications were noted.

Conclusions

Simultaneous multi-antenna MWA of liver tumours results in large nearly spherical ablation zones.

Key Points

• Simultaneous multi-antenna microwave ablation of liver tumours results in nearly spherical ablation zones.

• The multi-antenna approach generates oversized ablation volumes compared with the target tumour volume.

• The multi-antenna approach is safe.

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Fig. 1

Abbreviations

Dl:

Long diameter

Ds:

Short diameter

Dv:

Vertical diameter

MWA:

Microwave ablation

LTC:

Local tumour control

RI:

Roundness index

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Funding

The authors state that this work has not received any funding.

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Authors and Affiliations

  1. Service d’Imagerie Interventionnelle, Hôpitaux Universitaires de Strasbourg, 1, place de l’hopital, 67000, Strasbourg, France

    Roberto Luigi Cazzato, Pierre De Marini, Loïc Leclerc, Guillaume Koch, Pramod Rao, Pierre Auloge, Julien Garnon & Afshin Gangi

  2. Department of Diagnostic and Interventional Radiology, Guy’s and St. Thomas’ Hospitals NHS Foundation Trust, London, UK

    Danoob Dalili

  3. Section of Musculoskeletal Radiology, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA

    Danoob Dalili

Authors
  1. Roberto Luigi Cazzato
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  2. Pierre De Marini
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  3. Loïc Leclerc
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  4. Danoob Dalili
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  5. Guillaume Koch
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  6. Pramod Rao
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  7. Pierre Auloge
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  8. Julien Garnon
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  9. Afshin Gangi
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Corresponding author

Correspondence to Roberto Luigi Cazzato.

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Guarantor

The scientific guarantor of this publication is Afshin Gangi.

Conflict of interest

The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.

Statistics and biometry

No complex statistical methods were necessary for this paper.

Informed consent

Written informed consent was waived by the Institutional Review Board.

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Institutional Review Board approval was obtained.

Methodology

• retrospective

• observational

• performed at one institution

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Cazzato, R.L., De Marini, P., Leclerc, L. et al. Large nearly spherical ablation zones are achieved with simultaneous multi-antenna microwave ablation applied to treat liver tumours. Eur Radiol 30, 971–975 (2020). https://doi.org/10.1007/s00330-019-06431-1

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  • DOI: https://doi.org/10.1007/s00330-019-06431-1

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