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Tip malposition of peripherally inserted central catheters: a prospective randomized controlled trial to compare bedside insertion to fluoroscopically guided placement

  • Vascular-Interventional
  • Published:
European Radiology Aims and scope Submit manuscript

Abstract

Objective

Peripherally inserted central catheter (PICC) use continues to increase, leading to the development of a blind bedside technique (BST) for placement. The aim of our study was to compare the BST with the fluoroscopically guided technique (FGT), with specific regard to catheter tip position (CTP).

Materials and methods

One hundred eighty patients were randomized to either the BST or the FGT. All procedures were done by the same interventional team and included postprocedural chest X-ray to assess CTP. Depending on the international guidelines for optimal CTP, patients were classified in three types: optimal, suboptimal not needing repositioning, and nonoptimal requiring additional repositioning procedures. Fisher’s test was used for comparisons.

Results

One hundred seventy-one PICCs were successful inserted. In the BST groups, 23.3% of placements were suboptimal and 30% nonoptimal, requiring repositioning. In the FGT group, 5.6% were suboptimal and 1.1% nonoptimal. Thus, suboptimal and nonoptimal CTP were significantly lower in the FGT group (p < 0.001).

Conclusion

Tip malposition rates are high when using blind BST, exposing the patient to an increased risk of deep venous thrombosis and catheter malfunction. Using the FGT or emerging technologies that could help tip positioning are recommended, especially for long-term indications.

Key points

Bedside and fluoroscopy guided techniques are commonly used for PICC placement.

Catheter malposition is the major technical issue with the bedside technique.

Catheter malposition occurred in 53% of patients with the bedside technique.

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Abbreviations

PICC:

Peripherally inserted central catheters

BST:

Blind bedside technique

FGT:

Fluoroscopically guided technique

CTP:

Catheter tip position

CICV:

Centrally inserted venous catheters

SVC:

Superior vena cava

CAJ:

Cavoatrial junction

ICU:

Intensive care unit

References

  1. Amerasekera SS, Jones CM, Patel R, Cleasby MJ (2009) Imaging of the complications of peripherally inserted central venous catheters. Clin Radiol 64:832–840

    Article  CAS  PubMed  Google Scholar 

  2. Maki DG, Kluger DM, Crnich CJ (2006) The risk of bloodstream infection in adults with different intravascular devices: a systematic review of 200 published prospective studies. Mayo Clin Proc 81:1159–1171

    Article  PubMed  Google Scholar 

  3. Caers J, Fontaine C, Vinh-Hung V et al (2005) Catheter tip position as a risk factor for thrombosis associated with the use of subcutaneous infusion ports. Support Care Cancer 13:325–331

    Article  PubMed  Google Scholar 

  4. Verdino RJ (2006) The evolution of atrial fibrillation ablation from triggers to substrate. J Electrocardiol 39:S184–S187

    Article  PubMed  Google Scholar 

  5. Bivins MH, Callahan MJ (2000) Position-dependent ventricular tachycardia related to a peripherally inserted central catheter. Mayo Clin Proc 75:414–416

    Article  CAS  PubMed  Google Scholar 

  6. Orme RM, McSwiney MM, Chamberlain-Webber RF (2007) Fatal cardiac tamponade as a result of a peripherally inserted central venous catheter: a case report and review of the literature. Br J Anaesth 99:384–388

    Article  PubMed  Google Scholar 

  7. Johnston AJ, Holder A, Bishop SM, See TC, Streater CT (2014) Evaluation of the Sherlock 3CG Tip Confirmation System on peripherally inserted central catheter malposition rates. Anaesthesia 69:1322–1330

    Article  CAS  PubMed  Google Scholar 

  8. Baldinelli F, Capozzoli G, Pedrazzoli R, Marzano N (2015) Evaluation of the correct position of peripherally inserted central catheters: anatomical landmark vs. electrocardiographic technique. J Vasc Access 0:0

  9. Ragasa J, Shah N, Watson RC (1989) Where antecubital catheters go: a study under fluoroscopic control. Anesthesiology 71:378–380

    Article  CAS  PubMed  Google Scholar 

  10. LaRue GD (1995) Improving central placement rates of peripherally inserted catheters. J Intraven Nurs 18:24–27

    CAS  PubMed  Google Scholar 

  11. Burgess GE 3rd, Marino RJ, Peuler MJ (1977) Effect of head position on the location of venous catheters inserted via basilic veins. Anesthesiology 46:212–213

    Article  PubMed  Google Scholar 

  12. Schweickert WD, Herlitz J, Pohlman AS, Gehlbach BK, Hall JB, Kress JP (2009) A randomized, controlled trial evaluating postinsertion neck ultrasound in peripherally inserted central catheter procedures. Crit Care Med 37:1217–1221

    Article  PubMed  Google Scholar 

  13. Pittiruti M, Hamilton H, Biffi R, MacFie J, Pertkiewicz M (2009) ESPEN Guidelines on Parenteral Nutrition: central venous catheters (access, care, diagnosis and therapy of complications). Clin Nutr 28:365–377

    Article  PubMed  Google Scholar 

  14. Vesely TM (2003) Central venous catheter tip position: a continuing controversy. J Vasc Interv Radiol 14:527–534

    Article  PubMed  Google Scholar 

  15. Ridge CA, Litmanovich D, Molinari F, Bankier AA, Eisenberg RL (2013) Radiographic evaluation of central venous catheter position: anatomic correlation using gated coronary computed tomographic angiography. J Thorac Imaging 28:129–133

    Article  PubMed  Google Scholar 

  16. Fricke BL, Racadio JM, Duckworth T, Donnelly LF, Tamer RM, Johnson ND (2005) Placement of peripherally inserted central catheters without fluoroscopy in children: initial catheter tip position. Radiology 234:887–892

    Article  PubMed  Google Scholar 

  17. Trerotola SO, Thompson S, Chittams J, Vierregger KS (2007) Analysis of tip malposition and correction in peripherally inserted central catheters placed at bedside by a dedicated nursing team. J Vasc Interv Radiol 18:513–518

    Article  PubMed  Google Scholar 

  18. Minkovich L, Djaiani G, McCluskey SA, Mitsakakis N, Gilbert RW, Beattie WS (2011) Frequent malpositions of peripherally inserted central venous catheters in patients undergoing head and neck surgery. Can J Anaesth 58:709–713

    Article  PubMed  Google Scholar 

  19. Johnston AJ, Bishop SM, Martin L, See TC, Streater CT (2013) Defining peripherally inserted central catheter tip position and an evaluation of insertions in one unit. Anaesthesia 68:484–491

    Article  CAS  PubMed  Google Scholar 

  20. Pittiruti M, Bertollo D, Briglia E et al (2012) The intracavitary ECG method for positioning the tip of central venous catheters: results of an Italian multicenter study. J Vasc Access 13:357–365

    Article  PubMed  Google Scholar 

  21. Venkatesan T, Sen N, Korula PJ et al (2007) Blind placements of peripherally inserted antecubital central catheters: initial catheter tip position in relation to carina. Br J Anaesth 98:83–88

    Article  CAS  PubMed  Google Scholar 

  22. Ng PK, Ault MJ, Maldonado LS (1996) Peripherally inserted central catheters in the intensive care unit. J Intensive Care Med 11:49–54

    Article  CAS  PubMed  Google Scholar 

  23. Pinsky MR (1990) The effects of mechanical ventilation on the cardiovascular system. Crit Care Clin 6:663–678

    CAS  PubMed  Google Scholar 

  24. (2006) Infusion Nursing Standards of Practice. J Infus Nurs 29:S1–92

  25. Tian G, Chen B, Qi L, Zhu Y (2011) Modified insertion of a peripherally inserted central catheter: taking the chest radiograph earlier. Crit Care Nurse 31:64–69

    Article  PubMed  Google Scholar 

  26. Funaki B (2002) Central venous access: a primer for the diagnostic radiologist. AJR Am J Roentgenol 179:309–318

    Article  PubMed  Google Scholar 

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Acknowledgements

The scientific guarantor of this publication is Salah Dine Qanadli. The authors of this manuscript declare relationships with the following companies: Salah Dine Qanadli was a consultant for C. R Bard Inc. during the last 3 years. The authors state that this work has not received any funding. No complex statistical methods were necessary for this paper.

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Correspondence to Salah D. Qanadli.

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Glauser, F., Breault, S., Rigamonti, F. et al. Tip malposition of peripherally inserted central catheters: a prospective randomized controlled trial to compare bedside insertion to fluoroscopically guided placement. Eur Radiol 27, 2843–2849 (2017). https://doi.org/10.1007/s00330-016-4666-y

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  • DOI: https://doi.org/10.1007/s00330-016-4666-y

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