Abstract
Objective
To evaluate pelvic artery embolisation (PAE) in the emergency management of intractable postpartum haemorrhage (PPH) associated with placenta accreta (PA).
Methods
Forty such patients (PAE for PPH/PA) were retrospectively reviewed. Medical records were reviewed regarding the delivery and PAE procedure. Follow-up gynaecological outcomes after PAE were obtained by telephone interviews.
Results
Technical success was achieved in all women (100 %). The initial clinical success rate was 82.5 % (33/40). Three patients with PA underwent hysterectomy after PAE failed to stop the bleeding within 24 h after the embolisation. The other three patients underwent re-embolisation (two patients underwent re-embolisation on the next day and one patient had undergone re-embolisation 6 h after the first embolisation), and bleeding had stopped eventually. The clinical success rate was 92.5 %. There were four cases of immediate complications, such as, pelvic pain, nausea and urticaria. There were three late minor complications, temporary menopause, but no late major complications. After the procedure, 35 patients resumed normal menstruation, including two uncomplicated pregnancies. One patient expired owing to disseminated intravascular coagulopathy and intracerebral haemorrhage, despite successful embolisation.
Conclusion
PAE can be performed safely and effectively for patients with PPH and PA and can preserve the uterus in many patients.
Key Points
• Pelvic artery embolisation (PAE) is an important therapeutic option for postpartum haemorrhage.
• It seems safe and effective for PPH with placenta accreta (PA).
• PAE preserves the uterus and does not impair subsequent menstruation.
• PAE has few major complications.
Similar content being viewed by others
References
Combs CA, Murphy EL, Laros RK Jr (1991) Factors associated with hemorrhage in cesarean deliveries. Obstet Gynecol 77:77–82
Combs CA, Murphy EL, Laros RK Jr (1991) Factors associated with obstetric hemorrhage with vaginal birth. Obstet Gynecol 77:69–76
Lund CJ, Donavan JC (1967) Blood volume during pregnancy. Significance of plasma and red cell volumes. Am J Obstet Gynecol 98:394–403
Roberts WE (1995) Emergent obstetric management of obstetric hemorrhage. Obstet Gynecol Clin North Am 22:283–302
Eriksson L-G, Mulic-Lutvica A, Jangland L et al (2007) Massive obstetric hemorrhage treated with transcatheter arterial embolization: technical aspects and long-term effects on fertility and menstrual cycle. Acta Radiol 48:635–642
Mazouni C, Gorincour G, Juhan V et al (2008) Placenta accreta: a review of current advances in prenatal diagnosis. Placenta 28:599–603
Elsayes KM, Trout AT, Friedkin AM et al (2009) Imaging of the placenta: a multimodality pictorial, review. RadioGraphics 29:1371–1391
Bauer ST, Bonanno C (2009) Abnormal placentation. Semin Perinatol 33:88–96
American College of Obstetricians and Gynecologists (2006) ACOG practice bulletin: clinical management guidelines for obstetrician-gynecologists number 76, October 2006: postpartum hemorrhage. Obstet Gynecol 108:1039–1047
Hansch E, Chitkara U, McAlpine J et al (1999) Pelvic arterial embolization for control of obstetric hemorrhage: a five-year experience. Am J Obstet Gynecol 180:1454–1460
Mitty HA, Sterling KM, Alvarez M et al (1993) Obstetric hemorrhage: prophylactic and emergency arterial catheterization and embolotherapy. Radiology 188:183–187
Diop AN, Chabrot P, Bertrand A et al (2010) Placenta accreta: management with uterine artery embolization in 17 cases. J Vasc Interv Radiol 21:644–648
Trévor La Folie T, Vidal V, Mehanna M et al (2007) Results of endovascular treatment in cases of abnormal placentation with post-partum hemorrhage. J Obstet Gynaecol Res 33:624–630
Sofiah S, Med M, Late Y, Fung C et al (2009) Placenta accreta: clinical risk factors, accuracy of antenatal diagnosis and effect on pregnancy outcome. Med J Malaysia 64:298–302
Jung HN, Shin SW, Choi SJ et al (2011) Uterine artery embolization for emergent management of obstetric hemorrhage associated with placenta accreta. Acta Radiol 52:638–642
Deux JF, Bazot M, Le Blanche AF et al (2001) Is selective embolization of uterine arteries a safe alternative to hysterectomy in patients with obstetric hemorrhage? Am J Roentgenol 177:145–149
Drooz AT, Lewis CA, Allen TE et al (2003) Quality improvement guidelines for percutaneous transcatheter embolization. J Vasc Interv Radiol 14:S237–S242
The role of emergency and elective interventional radiology in postpartum haemorrhage www.rcog.org.uk/goodpractice; June 2007. No 6
Doumouchtsis SK, Papageorghiou A, Arulkumaran S (2007) Systematic review of conservative management of postpartum haemorrhage; what to do when medical treatment fails. Obstet Gynecol Surv 62:540–547
Hunter LA (2010) Exploring the role of uterine artery embolization in the management of obstetric hemorrhage. J Perinat Neonatal Nurs 24:207–214
Pelage JP, Le Dref O, Mateo J et al (1998) Life-threatening primary obstetric hemorrhage: Treatment with emergency selective arterial embolization. Radiology 208:359–362
Merland JJ, Houdart E, Herbreteau D et al (1996) Place of emergency arterial embolisation in obstetric haemorrhage about 16 personal cases. Eur J Obstet Gynecol Reprod Biol 65:141–143
Cravello L, Petrakian M, Roger V (2008) Placenta accreta: étiologies. Réalités en Gynécologie-Obstétrique 129:24
Clouqueur E, Rubod C, Paquin A et al (2008) Placenta accreta: diagnosis and management in a French type-3 maternity hospital. J Gynecol Obstet Biol Reprod (Paris) 37:499–504
Wu S, Kocherginsky M, Hibbard JU (2005) Abnormal placentation: twenty-year analysis. Am J Obstet Gynecol 192:1458–1461
Silver RM, Landon MB, Rouse DJ et al (2006) Maternal morbidity associated with multiple repeat cesarean deliveries. Obstet Gynecol 107:1226–1232
Choi SJ, Song SE, Jung KL et al (2008) Antepartum risk factors associated with peripartum cesarean hysterectomy in women with placenta previa. Am J Perinatol 25:37–41
Khong TY, Robertson WB (1987) Placenta creta and placenta praevia creta. Placenta 8:399–409
Siskin GP, Englander M, Stainken BF et al (2000) Embolic agents used for uterine fibroid embolization. AJR Am J Roentgenol 175:767–773
Quisling RG, Mickle JP, Ballinger WB et al (1984) Histopathologic analysis of intraarterial polyvinyl alcohol microemboli in rat cerebral cortex. AJNR Am J Neuroradiol 5:101–104
Chung SK, Kim JK, Yoon W et al (2003) Bronchial artery and non-bronchial systemic artery embolization for the treatment in patients with hemoptysis: analysis of efficacy of Gelfoam single use. J Korean Radiol Soc 49:15–22
Ganguli S, Faintuch S, Salazar GM et al (2008) Postembolization syndrome: changes in white blood cell counts immediately after uterine artery embolization. J Vasc Interv Radiol 19:443–445
Castells A, Bruix J, Ayuso C et al (1995) Transarterial embolization for hepatocellular carcinoma. Antibiotic prophylaxis and clinical meaning of postembolization fever. J Hepatol 22:410–415
Hascalik S, Celik O, Sarac K et al (2004) Transient ovarian failure: a rare complication of uterine fibroid embolization. Acta Obstet Gynecol Scand 83:682–685
Descargues G, Mauger Tinlot F, Douvrin F et al (2004) Menses, fertility and pregnancy after arterial embolization for the control of postpartum haemorrhage. Hum Reprod 19:339–343
Casele HL, Laifer SA (1997) Successful pregnancy after bilateral hypogastric artery ligation. A case report. J Reprod Med 42:306–308
Pelage JP, Le Dref O, Soyer P et al (1999) Prise en charge des hémorragies graves du post-partum par embolisation artérielle sélective. J Gynecol Obstet Biol Reprod 28:55–61
Dunson DB, Baird DD, Colombo B (2004) Increased infertility with age in men and women. Obstet Gynecol 103:51–56
Acknowledgments
The authors would like to thank the medical staff at all the departments visited for their cooperation in the data collection for the study.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Hwang, S.M., Jeon, G.S., Kim, M.D. et al. Transcatheter arterial embolisation for the management of obstetric haemorrhage associated with placental abnormality in 40 cases. Eur Radiol 23, 766–773 (2013). https://doi.org/10.1007/s00330-012-2612-1
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00330-012-2612-1