Skip to main content
Log in

Transcatheter arterial embolisation for the management of obstetric haemorrhage associated with placental abnormality in 40 cases

  • Interventional
  • Published:
European Radiology Aims and scope Submit manuscript

Abstract

Objective

To evaluate pelvic artery embolisation (PAE) in the emergency management of intractable postpartum haemorrhage (PPH) associated with placenta accreta (PA).

Methods

Forty such patients (PAE for PPH/PA) were retrospectively reviewed. Medical records were reviewed regarding the delivery and PAE procedure. Follow-up gynaecological outcomes after PAE were obtained by telephone interviews.

Results

Technical success was achieved in all women (100 %). The initial clinical success rate was 82.5 % (33/40). Three patients with PA underwent hysterectomy after PAE failed to stop the bleeding within 24 h after the embolisation. The other three patients underwent re-embolisation (two patients underwent re-embolisation on the next day and one patient had undergone re-embolisation 6 h after the first embolisation), and bleeding had stopped eventually. The clinical success rate was 92.5 %. There were four cases of immediate complications, such as, pelvic pain, nausea and urticaria. There were three late minor complications, temporary menopause, but no late major complications. After the procedure, 35 patients resumed normal menstruation, including two uncomplicated pregnancies. One patient expired owing to disseminated intravascular coagulopathy and intracerebral haemorrhage, despite successful embolisation.

Conclusion

PAE can be performed safely and effectively for patients with PPH and PA and can preserve the uterus in many patients.

Key Points

Pelvic artery embolisation (PAE) is an important therapeutic option for postpartum haemorrhage.

It seems safe and effective for PPH with placenta accreta (PA).

PAE preserves the uterus and does not impair subsequent menstruation.

PAE has few major complications.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Combs CA, Murphy EL, Laros RK Jr (1991) Factors associated with hemorrhage in cesarean deliveries. Obstet Gynecol 77:77–82

    PubMed  CAS  Google Scholar 

  2. Combs CA, Murphy EL, Laros RK Jr (1991) Factors associated with obstetric hemorrhage with vaginal birth. Obstet Gynecol 77:69–76

    PubMed  CAS  Google Scholar 

  3. Lund CJ, Donavan JC (1967) Blood volume during pregnancy. Significance of plasma and red cell volumes. Am J Obstet Gynecol 98:394–403

    PubMed  CAS  Google Scholar 

  4. Roberts WE (1995) Emergent obstetric management of obstetric hemorrhage. Obstet Gynecol Clin North Am 22:283–302

    PubMed  CAS  Google Scholar 

  5. Eriksson L-G, Mulic-Lutvica A, Jangland L et al (2007) Massive obstetric hemorrhage treated with transcatheter arterial embolization: technical aspects and long-term effects on fertility and menstrual cycle. Acta Radiol 48:635–642

    Article  PubMed  Google Scholar 

  6. Mazouni C, Gorincour G, Juhan V et al (2008) Placenta accreta: a review of current advances in prenatal diagnosis. Placenta 28:599–603

    Article  Google Scholar 

  7. Elsayes KM, Trout AT, Friedkin AM et al (2009) Imaging of the placenta: a multimodality pictorial, review. RadioGraphics 29:1371–1391

    Article  PubMed  Google Scholar 

  8. Bauer ST, Bonanno C (2009) Abnormal placentation. Semin Perinatol 33:88–96

    Article  PubMed  Google Scholar 

  9. American College of Obstetricians and Gynecologists (2006) ACOG practice bulletin: clinical management guidelines for obstetrician-gynecologists number 76, October 2006: postpartum hemorrhage. Obstet Gynecol 108:1039–1047

    Article  Google Scholar 

  10. Hansch E, Chitkara U, McAlpine J et al (1999) Pelvic arterial embolization for control of obstetric hemorrhage: a five-year experience. Am J Obstet Gynecol 180:1454–1460

    Article  PubMed  CAS  Google Scholar 

  11. Mitty HA, Sterling KM, Alvarez M et al (1993) Obstetric hemorrhage: prophylactic and emergency arterial catheterization and embolotherapy. Radiology 188:183–187

    PubMed  CAS  Google Scholar 

  12. Diop AN, Chabrot P, Bertrand A et al (2010) Placenta accreta: management with uterine artery embolization in 17 cases. J Vasc Interv Radiol 21:644–648

    Article  PubMed  Google Scholar 

  13. Trévor La Folie T, Vidal V, Mehanna M et al (2007) Results of endovascular treatment in cases of abnormal placentation with post-partum hemorrhage. J Obstet Gynaecol Res 33:624–630

    Article  PubMed  Google Scholar 

  14. Sofiah S, Med M, Late Y, Fung C et al (2009) Placenta accreta: clinical risk factors, accuracy of antenatal diagnosis and effect on pregnancy outcome. Med J Malaysia 64:298–302

    PubMed  CAS  Google Scholar 

  15. Jung HN, Shin SW, Choi SJ et al (2011) Uterine artery embolization for emergent management of obstetric hemorrhage associated with placenta accreta. Acta Radiol 52:638–642

    Article  PubMed  Google Scholar 

  16. Deux JF, Bazot M, Le Blanche AF et al (2001) Is selective embolization of uterine arteries a safe alternative to hysterectomy in patients with obstetric hemorrhage? Am J Roentgenol 177:145–149

    CAS  Google Scholar 

  17. Drooz AT, Lewis CA, Allen TE et al (2003) Quality improvement guidelines for percutaneous transcatheter embolization. J Vasc Interv Radiol 14:S237–S242

    PubMed  Google Scholar 

  18. The role of emergency and elective interventional radiology in postpartum haemorrhage www.rcog.org.uk/goodpractice; June 2007. No 6

  19. Doumouchtsis SK, Papageorghiou A, Arulkumaran S (2007) Systematic review of conservative management of postpartum haemorrhage; what to do when medical treatment fails. Obstet Gynecol Surv 62:540–547

    Article  PubMed  Google Scholar 

  20. Hunter LA (2010) Exploring the role of uterine artery embolization in the management of obstetric hemorrhage. J Perinat Neonatal Nurs 24:207–214

    PubMed  Google Scholar 

  21. Pelage JP, Le Dref O, Mateo J et al (1998) Life-threatening primary obstetric hemorrhage: Treatment with emergency selective arterial embolization. Radiology 208:359–362

    PubMed  CAS  Google Scholar 

  22. Merland JJ, Houdart E, Herbreteau D et al (1996) Place of emergency arterial embolisation in obstetric haemorrhage about 16 personal cases. Eur J Obstet Gynecol Reprod Biol 65:141–143

    Article  PubMed  CAS  Google Scholar 

  23. Cravello L, Petrakian M, Roger V (2008) Placenta accreta: étiologies. Réalités en Gynécologie-Obstétrique 129:24

    Google Scholar 

  24. Clouqueur E, Rubod C, Paquin A et al (2008) Placenta accreta: diagnosis and management in a French type-3 maternity hospital. J Gynecol Obstet Biol Reprod (Paris) 37:499–504

    Article  CAS  Google Scholar 

  25. Wu S, Kocherginsky M, Hibbard JU (2005) Abnormal placentation: twenty-year analysis. Am J Obstet Gynecol 192:1458–1461

    Article  PubMed  Google Scholar 

  26. Silver RM, Landon MB, Rouse DJ et al (2006) Maternal morbidity associated with multiple repeat cesarean deliveries. Obstet Gynecol 107:1226–1232

    Article  PubMed  Google Scholar 

  27. Choi SJ, Song SE, Jung KL et al (2008) Antepartum risk factors associated with peripartum cesarean hysterectomy in women with placenta previa. Am J Perinatol 25:37–41

    Article  PubMed  Google Scholar 

  28. Khong TY, Robertson WB (1987) Placenta creta and placenta praevia creta. Placenta 8:399–409

    Article  PubMed  CAS  Google Scholar 

  29. Siskin GP, Englander M, Stainken BF et al (2000) Embolic agents used for uterine fibroid embolization. AJR Am J Roentgenol 175:767–773

    PubMed  CAS  Google Scholar 

  30. Quisling RG, Mickle JP, Ballinger WB et al (1984) Histopathologic analysis of intraarterial polyvinyl alcohol microemboli in rat cerebral cortex. AJNR Am J Neuroradiol 5:101–104

    PubMed  CAS  Google Scholar 

  31. Chung SK, Kim JK, Yoon W et al (2003) Bronchial artery and non-bronchial systemic artery embolization for the treatment in patients with hemoptysis: analysis of efficacy of Gelfoam single use. J Korean Radiol Soc 49:15–22

    Google Scholar 

  32. Ganguli S, Faintuch S, Salazar GM et al (2008) Postembolization syndrome: changes in white blood cell counts immediately after uterine artery embolization. J Vasc Interv Radiol 19:443–445

    Article  PubMed  Google Scholar 

  33. Castells A, Bruix J, Ayuso C et al (1995) Transarterial embolization for hepatocellular carcinoma. Antibiotic prophylaxis and clinical meaning of postembolization fever. J Hepatol 22:410–415

    Article  PubMed  CAS  Google Scholar 

  34. Hascalik S, Celik O, Sarac K et al (2004) Transient ovarian failure: a rare complication of uterine fibroid embolization. Acta Obstet Gynecol Scand 83:682–685

    PubMed  Google Scholar 

  35. Descargues G, Mauger Tinlot F, Douvrin F et al (2004) Menses, fertility and pregnancy after arterial embolization for the control of postpartum haemorrhage. Hum Reprod 19:339–343

    Article  PubMed  CAS  Google Scholar 

  36. Casele HL, Laifer SA (1997) Successful pregnancy after bilateral hypogastric artery ligation. A case report. J Reprod Med 42:306–308

    PubMed  CAS  Google Scholar 

  37. Pelage JP, Le Dref O, Soyer P et al (1999) Prise en charge des hémorragies graves du post-partum par embolisation artérielle sélective. J Gynecol Obstet Biol Reprod 28:55–61

    CAS  Google Scholar 

  38. Dunson DB, Baird DD, Colombo B (2004) Increased infertility with age in men and women. Obstet Gynecol 103:51–56

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

The authors would like to thank the medical staff at all the departments visited for their cooperation in the data collection for the study.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Gyeong Sik Jeon.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hwang, S.M., Jeon, G.S., Kim, M.D. et al. Transcatheter arterial embolisation for the management of obstetric haemorrhage associated with placental abnormality in 40 cases. Eur Radiol 23, 766–773 (2013). https://doi.org/10.1007/s00330-012-2612-1

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00330-012-2612-1

Keywords

Navigation