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New observations from MR velocity-encoded flow measurements concerning diastolic function in constrictive pericarditis

  • Cardiac
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Abstract

Objective

To assess diastolic function in patients with constrictive pericarditis (CP) by using velocity-encoded flow measurements at the atrioventricular valves and to evaluate whether conclusions regarding increased ventricular pressure can be drawn.

Methods

Twenty-two patients with CP and 20 healthy subjects were examined on a 1.5-T MR system. In addition to evaluation of pericardial thickness, ventricular volumes and septal movement, velocity-encoded flow measurements were performed at the level of the atrioventricular valves for assessment of diastolic function. Amplitudes of the e- and a-waves were measured and e- to a-wave ratios were calculated. The correlation of transtricuspid e- to a-wave ratios and right ventricular end-diastolic pressures (RVEDP) was calculated.

Results

Right ventricular volumes were significantly smaller in patients with CP (p < 0.001). Abnormal septal movement was detected in all patients except one with CP and in none of the healthy subjects. In patients with CP mean transtricuspid e- to a-wave ratios were significantly smaller compared with healthy subjects. Individual transtricuspid e- to a-wave ratios were highly correlated with RVEDP (r = 0.6, p = 0.01).

Conclusions

An elaborate MR examination can identify patients with CP. Velocity-encoded flow measurements with calculation of transtricuspid e- to a-wave ratios are a valuable tool for detection of diastolic dysfunction in patients with CP. The value of e- to a-wave ratios may indicate elevated RVEDP.

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Authors and Affiliations

  1. Department of Clinical Radiology, University Hospitals–Campus Grosshadern, Ludwig-Maximilian University, Marchioninistr. 15, 81377, Munich, Germany

    Kerstin Bauner, A. Horng, M. Reiser & A. Huber

  2. Department of Cardiac Surgery, University Hospitals–Campus Grosshadern, Ludwig-Maximilian University, Marchioninistr. 15, 81377, Munich, Germany

    Ch. Schmitz

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  1. Kerstin Bauner
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  2. A. Horng
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  3. Ch. Schmitz
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  4. M. Reiser
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  5. A. Huber
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Correspondence to Kerstin Bauner.

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Bauner, K., Horng, A., Schmitz, C. et al. New observations from MR velocity-encoded flow measurements concerning diastolic function in constrictive pericarditis. Eur Radiol 20, 1831–1840 (2010). https://doi.org/10.1007/s00330-010-1741-7

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  • DOI: https://doi.org/10.1007/s00330-010-1741-7

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