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Transarterial chemoembolization in the treatment of hepatoblastoma in children

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Abstract

Hepatoblastoma is one of the clinical challenges in children, as it is common and frequently unresectable. Chemotherapy can be administered regionally instead of systemically by transarterial chemoembolization (TACE) and thus improve prognosis. The advantages of this technique over systemic chemotherapy led to developing its role from being a palliative or an adjuvant preoperative treatment to being a potentially independent palliative or curative therapeutic option. The technical aspects and complications of a combined transarterial administration of chemotherapeutic and vascular occlusive agents in cases of hepatoblastoma in children are discussed, to give a comprehensive idea about the value of TACE in this context.

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References

  1. Ohtsuka Y, Matsunaga T, Yoshida H, Kouchi K, Okada T, Ohnuma N (2004) Optimal strategy of preoperative transcatheter arterial chemoembolization for hepatoblastoma. Surg Today 34(2):127–133

    Article  PubMed  Google Scholar 

  2. Malogolowkin MH, Stanley P, Steele DA, Ortega JA (2000) Feasibility and toxicity of chemoembolization for children with liver tumors. J Clin Oncol 18(6):1279–1284

    PubMed  CAS  Google Scholar 

  3. Tashjian DB, Moriarty KP, Courtney RA, Bean MS, Steele DA (2002) Preoperative chemoembolization for unresectable hepatoblastoma. Pediatr Surg Int 18(2–3):187–189

    Article  PubMed  Google Scholar 

  4. Arcement CM, Towbin RB, Meza MP, Gerber DA, Kaye RD, Mazariegos GV, Carr BI, Reyes J (2000) Intrahepatic chemoembolization in unresectable pediatric liver malignancies. Pediatr Radiol 30(11):779–785

    Article  PubMed  CAS  Google Scholar 

  5. Latoo MY, Oliver A, Roebuck (2002) Anaesthetic management of hepatic artery chemoembolization in a paediatric patient. Paediatr Anaesth 12(7):629–631

    Article  PubMed  CAS  Google Scholar 

  6. Geiger JD (1996) Surgery for hepatoblastoma in children. Curr Opin Pediatr 8(3):276–282

    Article  PubMed  CAS  Google Scholar 

  7. Farhi DC, Odell CA, Shurin SB (1993) Myelodysplastic syndrome and acute myeloid leukemia after treatment for solid tumors of childhood. Am J Clin Pathol 100:270–275

    PubMed  CAS  Google Scholar 

  8. Moppet J, Oakhill A, Duncan AW (2001) Second malignancies in children: the usual suspects? Eur J Radiol 38:325–348

    Google Scholar 

  9. Van Thiel DH, Carr B, Iwatsuki S et al (1993) The 11-year Pittsburg experience with liver transplantation for hepatocellular carcinoma. J Surg Oncol Suppl 3:78–82

    Article  PubMed  Google Scholar 

  10. Hu X, Li J, Jiang X, Chen Z (2004) Cure of hepatoblastoma with transcatheter arterial chemoembolization. J Ped Haematol/Oncol 26(1):60–63

    Article  Google Scholar 

  11. Yamaura K, Higashi M, Akiyoshi K, Itonaga Y, Inoue H, Takahashi S (2000) Pulmonary lipiodol embolism during transcatheter arterial chemoembolization for hepatoblastoma under general anesthesia. Eur J Anaesthesiol 17(11):704–708

    Article  PubMed  CAS  Google Scholar 

  12. Chou FI, Fang KC, Chung C, Lui WY, Chi CW, Liu RS, Chan WK (1995) Lipiodol uptake and retention by human hepatoma cells. Nucl Med Biol 22(3):379–386

    Article  PubMed  CAS  Google Scholar 

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Correspondence to Thomas J. Vogl.

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Vogl, T.J., Scheller, A., Jakob, U. et al. Transarterial chemoembolization in the treatment of hepatoblastoma in children. Eur Radiol 16, 1393–1396 (2006). https://doi.org/10.1007/s00330-005-2827-5

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  • DOI: https://doi.org/10.1007/s00330-005-2827-5

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