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Importance of extracolonic findings at IV contrast medium-enhanced CT colonography versus those at non-enhanced CT colonography

  • Gastrointestinal
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Abstract

To compare the clinical importance of extracolonic findings at intravenous (IV) contrast-enhanced CT colonography versus those at non-enhanced CT colonography. IV contrast medium-enhanced (n=72) and non-enhanced (n=30) multidetector CT colonography was performed in 102 symptomatic patients followed by conventional colonoscopy on the same day. The impact of extracolonic findings on further work up and treatment was assessed by a review of patient records. Extracolonic findings were divided into two groups: either leading to further work up respectively having an impact on therapy or not. A total of 303 extracolonic findings were detected. Of those, 71% (215/303) were found on IV contrast-enhanced CT, and 29% (88/303) were found on non-enhanced CT colonography. The extracolonic findings in 25% (26/102) of all patients led to further work up or had an impact on therapy. Twenty-two of these patients underwent CT colonography with IV contrast enhancement, and four without. The percentage of extracolonic findings leading to further work up or having an impact on therapy was higher for IV contrast-enhanced (31%; 22/72) than for non-enhanced (13%; 4/30) CT scans (P=0.12). IV contrast-enhanced CT colonography produced more extracolonic findings than non-enhanced CT colonography. A substantially greater proportion of findings on IV contrast-enhanced CT colonography led to further work up and treatment than did non-enhanced CT colonography.

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Acknowledgements

This study was supported by a research grant from the Helmut-Horten-Foundation, Lugano, Switzerland. The authors wish to thank the CT technologists at the Institute of Radiology, Inselspital Bern, for their excellent expert assistance.

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Authors and Affiliations

  1. Institute of Diagnostic Radiology, Inselspital, University of Bern, Freiburgstrasse 10, 3010, Bern, Switzerland

    Adrian Spreng, Joerg Mattich, Hans-Peter Dinkel, Peter Vock & Hanno Hoppe

  2. Department of Gastroenterology, Inselspital, University of Bern, Bern, Switzerland

    Peter Netzer

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  1. Adrian Spreng
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  2. Peter Netzer
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  3. Joerg Mattich
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  4. Hans-Peter Dinkel
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  5. Peter Vock
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  6. Hanno Hoppe
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Correspondence to Hanno Hoppe.

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Spreng, A., Netzer, P., Mattich, J. et al. Importance of extracolonic findings at IV contrast medium-enhanced CT colonography versus those at non-enhanced CT colonography. Eur Radiol 15, 2088–2095 (2005). https://doi.org/10.1007/s00330-005-2798-6

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  • DOI: https://doi.org/10.1007/s00330-005-2798-6

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