Abstract
The aim of this study was to evaluate CT and MRI findings in xanthogranulomatous cholecystitis (XGC) and to correlate the imaging findings with various pathologic parameters. The study included 13 patients with histopathologically confirmed XGC. The CT (n=13) and MRI (n=5) obtained in these patients were evaluated retrospectively. On CT, low-attenuation areas in the wall of XGC correlated with foam and inflammatory cells or necrosis and/or abscess in XGC. Areas of iso- to slightly high signal intensity on T2-weighted images, showing slight enhancement at early phase and strong enhancement at last phase on dynamic study, corresponded with areas of abundant xanthogranulomas. Areas with very high signal intensity on T2-weighted images without enhancement corresponded with necrosis and/or abscesses. Luminal surface enhancement (LSE) of gallbladder wall represented preservation of the epithelial layer. The early-enhanced areas of the liver bed on dynamic CT and MR images corresponded with accumulation of inflammatory cells and abundant fibrosis. Our results indicate that CT and MRI findings correlate well with the histopathologic findings of XGC.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Dao AH, Wong SW, Adkins RB Jr et al. (1989) Xanthogranulomatous cholecystitis: a clinical and pathologic study of 12 cases. Am Surg 55:32–35
Christensen AH et al. (1970) Benign tumors and pseudotumors of the gallbladder: report of 180 cases. Arch Pathol 90:423–432
Kim PN et al. (1999) Xanthogranulomatous cholecystitis: radiologic findings with histologic correlation that focus on intramural nodules. AJR 172:949–953
Chun KA, Ha HK, Auh YH et al. (1997) Xanthogranulomatous cholecystitis: CT features with emphasis on differentiation from gallbladder carcinoma. Radiology 203:93–97
Furuta A, Ishibashi T, Sakamoto K et al. (1996) MR imaging of xanthogranulomatous cholecystitis. Radiat Med 14:315–319
Korobkin M, Lombardi TJ, Aisen AM et al. (1995) Characterization of adrenal masses with chemical shift and gadolinium-enhanced MR imaging. Radiology 197:411–418
Kim MJ, OH YT, Mitchell DG et al. (1999) Gallbladder adenomyomatosis: findings on MRI. Abdom Imaging 24:410–413
Yoshimatsu K, Honda H, Jim M et al. (1999) MR diagnosis of adenomyomatousis of the gallbladder and differentiation from gallbladder carcinoma: importance of showing Rokitansky-Aschoff sinuses. AJR 172:1535–1540
Matsui O et al. (1987) Staining in the liver surrounding gallbladder fossa on hepatic angiography caused by increased cystic venous drainage. Gastrointest Radiol 12:307–312
Yamashita K et al. (1995) CT finding of transient focal increased attenuation of liver adjacent to the gallbladder in acute cholecystitis. AJR 164:343–346
Ito K, Awaya H, Matsunaga N et al. (1997) Gall bladder disease: appearance of associated transient increased attenuation in the liver at biphasic, contrast-enhanced dynamic CT. Radiology 204:723–728
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Shuto, R., Kiyosue, H., Komatsu, E. et al. CT and MR imaging findings of xanthogranulomatous cholecystitis: correlation with pathologic findings. Eur Radiol 14, 440–446 (2004). https://doi.org/10.1007/s00330-003-1931-7
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00330-003-1931-7