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Reliability and validity of the 12-item WHODAS 2.0 in patients with Kashin–Beck disease

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Abstract

The purpose of this study was to check the reliability and validity of the 12-item Chinese version of the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) for the assessment of disability in patients with Kashin–Beck disease (KBD). We recruited 219 patients with KBD from the high-risk KBD area in the Shaanxi province, using stratified multistage random sampling. We assessed each patient using the Chinese version of the 12-item WHODAS 2.0 and the Western Ontario and McMaster Universities Index of Osteoarthritis (WOMAC). Statistical evaluations of the instruments consisted of Cronbach’s alpha, intraclass correlation coefficient (ICC), confirmatory factor analysis (CFA), and Pearson’s correlation coefficient. Cronbach’s alpha and ICC for the six domains ranged from 0.704 to 0.906 and 0.690 to 0.852, respectively. A six-factor structure fits the data well (CFI = 0.967, TLI = 0.944, RMSEA = 0.08). Regarding convergent validity, the four domains of the 12-item WHODAS 2.0 (getting around, self-care, life activity, and participation) showed moderate-to-strong correlation for all three domains of the WOMAC (0.428 < |r| < 0.804). Regarding divergent validity, the two domains of the 12-item WHODAS 2.0 (understanding and communication, and getting along with people) showed weak correlation for the three domains of WOMAC (0.182 < |r| < 0.295). The Chinese version of 12-item WHODAS 2.0 questionnaire is a reliable and valid instrument when administered to KBD patients.

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Acknowledgements

We would like to thank all study volunteers and their family members. We also would like to thank all CDC staff of Linyou and Yongshou counties for supporting our data collection.

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Correspondence to Hua Fang or Xiong Guo.

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Funding

This study was financially supported by grants of the National Natural Science Foundation of China (Nos. 81302393 and 81620108026).

Conflict of interest

The authors Mohammad Imran Younus, Di-Miao Wang, Fang-fang Yu, Hua Fang, Xiong Guo declare that they have no conflict of interest to disclose.

Ethical approval

All procedures performed in studies involving participants were in accordance with the ethical standards of the institutional and/or national research committee, and with the 1964 Helsinki declaration, and its later amendments, or comparable ethical standards. The study was performed after consultation with, and with the approval of (approval no. 2013-084), the Ethical Review Committee of Xi’an Jiaotong University School of Medicine.

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Informed consent was obtained from all individuals participants included in the study.

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Younus, M.I., Wang, DM., Yu, Ff. et al. Reliability and validity of the 12-item WHODAS 2.0 in patients with Kashin–Beck disease. Rheumatol Int 37, 1567–1573 (2017). https://doi.org/10.1007/s00296-017-3723-4

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  • DOI: https://doi.org/10.1007/s00296-017-3723-4

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