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Determinants of health-related quality of life impairment in Egyptian children and adolescents with juvenile idiopathic arthritis: Sharkia Governorate

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Abstract

The aim of this study was to identify the possible determinants of impaired health-related quality of life (HRQOL) in Egyptian children and adolescents with juvenile idiopathic arthritis (JIA). Fifty-eight consecutive patients of JIA aged from 8 to 18 years underwent assessment of socio-economic and demographic characteristics; HRQOL using Pediatric Quality of Life Inventory 4.0 Generic Core Scale, disease activity using the Juvenile Arthritis Disease Activity Score based on 27 joints (JADAS-27), functional ability using the childhood health assessment questionnaire (CHAQ), pain score on visual analog scale and psychological symptoms using the Children’s Depression Inventory (CDI) score. Multivariate modeling was applied to determine the factors that associated with HRQOL impairment. A total of 55 % of the patients (32 of 58) had impaired HRQOL (<78.6). In multiple regression analyses, high CHAQ scores (OR 6.0, 95 % CI 2.0–17.5, P = 0.001), pain (OR 3.1, 95 % CI 1.9–6.3, P = 0.01), stop going to school (OR 3.9, 95 % CI 2.0–7.3, P = 0.01), low socioeconomic status (OR 2.3, 95 % CI 1.09–4.7, P = 0.04) and high psychological symptoms (OR 4.2, 95 % CI 2.0–12.6, P = 0.001) were determinants for HRQOL impairment. HRQOL impairment is a significant problem in Egyptian children and adolescents with JIA. These findings underscore the critical need for monitoring of HRQOL in these patients. More attention should be given to JIA patients who stop going to school and who has low socioeconomic status.

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Authors and Affiliations

  1. Department of Rheumatology and Rehabilitation, University of Zagazig, Sharkia, Egypt

    Amal B. Abdul-Sattar, Enass A. Elewa & Eman El-Dessoky El-Shahawy

  2. Department of Community Medicine and Public Health, Faculty of Medicine, University of Zagazig, Sharkia, Egypt

    Eman H. Waly

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  1. Amal B. Abdul-Sattar
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  2. Enass A. Elewa
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  3. Eman El-Dessoky El-Shahawy
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  4. Eman H. Waly
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Correspondence to Eman El-Dessoky El-Shahawy.

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Abdul-Sattar, A.B., Elewa, E.A., El-Shahawy, E.ED. et al. Determinants of health-related quality of life impairment in Egyptian children and adolescents with juvenile idiopathic arthritis: Sharkia Governorate. Rheumatol Int 34, 1095–1101 (2014). https://doi.org/10.1007/s00296-014-2950-1

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  • DOI: https://doi.org/10.1007/s00296-014-2950-1

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