Abstract
This study is aimed at retrospectively studying cancer-associated inflammatory myopathies (CAM) in a cohort of patients with inflammatory myopathies. CAM were diagnosed if the tumor was diagnosed 2 years before or after disease onset. One hundred and sixty-two patients were included, 27 (17 %) had CAM. A significant association was observed between CAM and dermatomyositis (DM), older age and dysphagia at disease onset. CAM have lower creatine kinase (CK) levels at onset and a low prevalence of autoantibodies. In conclusion, the association of male sex, older age, DM, dysphagia at onset, lower CK, and autoantibodies negativity carries a high suspicion of CAM.
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Neri, R., Simone, B., Iacopetti, V. et al. Cancer-associated myositis: a 35-year retrospective study of a monocentric cohort. Rheumatol Int 34, 565–569 (2014). https://doi.org/10.1007/s00296-013-2910-1
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DOI: https://doi.org/10.1007/s00296-013-2910-1