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Risk factors for and prevalence of knee osteoarthritis in the rural areas of Shanxi Province, North China: a COPCORD study

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Abstract

The purpose of this study is to investigate the prevalence of knee osteoarthritis (OA) in the rural areas of Shanxi Province, North China. A total of 7,126 permanent residents aged from 16 to 90 years were surveyed using Community Oriented Program for the Control of Rheumatic Diseases methodology. Diagnosis of knee OA was reached according to the examination results by 3 rheumatologists. Possible risk factors for knee OA were analyzed. Among the 7,126 participants, 983 cases were diagnosed with knee OA. Of the 983 cases, 446 were male (12.4 %) and 537 were female (15.3 %). The overall prevalence of knee OA was 13.8 %. The prevalence rate of knee pain was significantly higher in women than in men. There was a tendency of increased knee OA prevalence with age, especially after 40 years old. Participants with higher body mass index (BMI) showed a higher prevalence rate of knee OA than those with lower BMI. Multivariable analysis indicates age, gender, dietary bias, underground work history, BMI, waist-to-hip ratio (WHR), and concomitant cardiovascular diseases (CSDs) are risk factors for knee OA in rural Shanxi. The prevalence of knee OA in the rural areas of Shanxi Province is high. Age, gender, dietary bias, underground work history, BMI, WHR, and CSDs are risk factors for knee OA. Primary and secondary prevention programs aimed at improving ventilation condition, reducing obesity, and treating concomitant cardiovascular diseases are required.

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References

  1. Lopez AD, Murray CC (1998) The global burden of disease, 1990–2020. Nat Med 4:1241–1243

    Article  PubMed  CAS  Google Scholar 

  2. Murray CJ, Lopez AD, Jamison DT (1994) The global burden of disease in 1990: summary results, sensitivity analysis and future directions. Bull World Health Organ 72:495–509

    PubMed  CAS  Google Scholar 

  3. Felson DT, Zhang Y (1998) An update on the epidemiology of knee and hip osteoarthritis with a view to prevention. Arthritis Rheum 41:1343–1355

    Article  PubMed  CAS  Google Scholar 

  4. van Saase JL, van Romunde LK, Cats A, Vandenbroucke JP, Valkenburg HA (1989) Epidemiology of osteoarthritis: Zoetermeer survey. Comparison of radiological osteoarthritis in a Dutch population with that in 10 other populations. Ann Rheum Dis 48:271–280

    Article  PubMed  Google Scholar 

  5. Woolf AD, Akesson K (2001) Understanding the burden of musculoskeletal conditions. The burden is huge and not reflected in national health priorities. BMJ 322:1079–1080

    Article  PubMed  CAS  Google Scholar 

  6. Veerapen K, Wigley RD, Valkenburg H (2007) Musculoskeletal pain in Malaysia: a COPCORD survey. J Rheumatol 34:207–213

    PubMed  Google Scholar 

  7. Zeng QY, Chen R, Xiao ZY, Huang SB, Liu Y, Xu JC, Chen SL, Darmawan J, Couchman KG, Wigley RD, Muirden KD (2004) Low prevalence of knee and back pain in southeast China; the Shantou COPCORD study. J Rheumatol 31:2439–2443

    PubMed  Google Scholar 

  8. Kang X, Fransen M, Zhang Y, Li H, Ke Y, Lu M, Su S, Song X, Guo Y, Chen J, Niu J, Felson D, Lin J (2009) The high prevalence of knee osteoarthritis in a rural Chinese population: the Wuchuan osteoarthritis study. Arthritis Rheum 61:641–647

    Article  PubMed  Google Scholar 

  9. Cooper C, Snow S, McAlindon TE, Kellingray S, Stuart B, Coggon D, Dieppe PA (2000) Risk factors for the incidence and progression of radiographic knee osteoarthritis. Arthritis Rheum 43:995–1000

    Article  PubMed  CAS  Google Scholar 

  10. Haq SA, Darmawan J, Islam MN, Uddin MZ, Das BB, Rahman F, Chowdhury MA, Alam MN, Mahmud TA, Chowdhury MR, Tahir M (2005) Prevalence of rheumatic diseases and associated outcomes in rural and urban communities in Bangladesh: a COPCORD study. J Rheumatol 32:348–353

    PubMed  Google Scholar 

  11. Zeng QY, Zang CH, Li XF, Dong HY, Zhang AL, Lin L (2006) Associated risk factors of knee osteoarthritis: a population survey in Taiyuan, China. Chin Med J (Engl) 119:1522–1527

    Google Scholar 

  12. Zhang N, Shi Q, Zhang X (1995) An epidemiological study of knee osteoarthritis. Zhonghua Nei Ke Za Zhi 34:84–87

    PubMed  CAS  Google Scholar 

  13. Zeng Q, Huang S, Chen R (1997) 10-year epidemiological study on rheumatic diseases in Shantou area. Zhonghua Nei Ke Za Zhi 36:193–197

    PubMed  CAS  Google Scholar 

  14. Kellgren JH, Lawrence JS (1957) Radiological assessment of osteo-arthrosis. Ann Rheum Dis 16:494–502

    Article  PubMed  CAS  Google Scholar 

  15. Zhou B (2002) Predictive values of body mass index and waist circumference to risk factors of related diseases in Chinese adult population. Zhonghua Liu Xing Bing Xue Za Zhi 23:5–10

    PubMed  Google Scholar 

  16. Du H, Chen SL, Bao CD, Wang XD, Lu Y, Gu YY, Xu JR, Chai WM, Chen J, Nakamura H, Nishioka K (2005) Prevalence and risk factors of knee osteoarthritis in Huang-Pu District, Shanghai, China. Rheumatol Int 25:585–590

    Article  PubMed  Google Scholar 

  17. Tangtrakulwanich B, Geater AF, Chongsuvivatwong V (2006) Prevalence, patterns, and risk factors of knee osteoarthritis in Thai monks. J Orthop Sci 11:439–445

    Article  PubMed  Google Scholar 

  18. Grotle M, Hagen KB, Natvig B, Dahl FA, Kvien TK (2008) Obesity and osteoarthritis in knee, hip and/or hand: an epidemiological study in the general population with 10 years follow-up. BMC Musculoskelet Disord 9:132

    Article  PubMed  Google Scholar 

  19. Gabbe BJ, Finch CF, Bennell KL, Wajswelner H (2005) Risk factors for hamstring injuries in community level Australian football. Br J Sports Med 39:106–110

    Article  PubMed  CAS  Google Scholar 

  20. Felson DT, Naimark A, Anderson J, Kazis L, Castelli W, Meenan RF (1987) The prevalence of knee osteoarthritis in the elderly. The Framingham Osteoarthritis Study. Arthritis Rheum 30:914–918

    Article  PubMed  CAS  Google Scholar 

  21. Lau EC, Cooper C, Lam D, Chan VN, Tsang KK, Sham A (2000) Factors associated with osteoarthritis of the hip and knee in Hong Kong Chinese: obesity, joint injury, and occupational activities. Am J Epidemiol 152:855–862

    Article  PubMed  CAS  Google Scholar 

  22. Hoogeboom TJ, Snijders GF, Cats HA, de Bie RA, Bierma-Zeinstra SM, van den Hoogen FH, van Riel PL, Emans PJ, Wesseling J, den Broeder AA, van den Ende CH (2012) Prevalence and predictors of health care use in patients with early hip or knee osteoarthritis: two-year follow-up data from the CHECK cohort. Osteoarthr Cartil 20:525–531

    Article  PubMed  CAS  Google Scholar 

  23. Kopec JA, Rahman MM, Berthelot JM, Le Petit C, Aghajanian J, Sayre EC, Cibere J, Anis AH, Badley EM (2007) Descriptive epidemiology of osteoarthritis in British Columbia, Canada. J Rheumatol 34:386–393

    PubMed  Google Scholar 

  24. Coggon D, Croft P, Kellingray S, Barrett D, McLaren M, Cooper C (2000) Occupational physical activities and osteoarthritis of the knee. Arthritis Rheum 43:1443–1449

    Article  PubMed  CAS  Google Scholar 

  25. Loughlin J, Carr A, Chapman K (2005) The common HFE variants C282Y and H63D are not associated with primary OA of the hip or knee. J Rheumatol 32:391–392; author reply 392

    Google Scholar 

  26. Felson DT (1988) Epidemiology of hip and knee osteoarthritis. Epidemiol Rev 10:1–28

    PubMed  CAS  Google Scholar 

  27. Felson DT, Hannan MT, Naimark A, Berkeley J, Gordon G, Wilson PW, Anderson J (1991) Occupational physical demands, knee bending, and knee osteoarthritis: results from the Framingham Study. J Rheumatol 18:1587–1592

    PubMed  CAS  Google Scholar 

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Acknowledgments

This study was sponsored by National Natural Science Foundation of China (No. 81102198) and Department of Health, Shanxi Province (No. 200754).

Conflict of interest

The authors declare there is no conflict of interest.

Author information

Authors and Affiliations

  1. Department of Health Statistics, School of Public Health, Shanxi Medical University, 56 South Xinjian Road, Taiyuan, 030001, China

    Junfeng Zhang, Guifen Liu, Ailian Zhang & Zhiyong Liu

  2. Publishing House of Chinese Journal of Rheumatology, Taiyuan, 030013, China

    Junfeng Zhang & Haiyuan Dong

  3. Shanxi Cardiovascular Hospital, Taiyuan, 030024, China

    Linghua Song

  4. The Second Hospital of Shanxi Medical University, Taiyuan, 030001, China

    Xiaofeng Li & Jing Luo

Authors
  1. Junfeng Zhang
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  2. Linghua Song
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  3. Guifen Liu
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  4. Ailian Zhang
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  5. Haiyuan Dong
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  6. Zhiyong Liu
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  7. Xiaofeng Li
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  8. Jing Luo
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Corresponding author

Correspondence to Guifen Liu.

Additional information

Junfeng Zhang and Linghua Song contributed equally to this study and should be considered as first authors.

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Zhang, J., Song, L., Liu, G. et al. Risk factors for and prevalence of knee osteoarthritis in the rural areas of Shanxi Province, North China: a COPCORD study. Rheumatol Int 33, 2783–2788 (2013). https://doi.org/10.1007/s00296-013-2809-x

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  • DOI: https://doi.org/10.1007/s00296-013-2809-x

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