Skip to main content

Advertisement

Log in

Carpal tunnel syndrome and metabolic syndrome co-occurrence

  • Original Article
  • Published:
Rheumatology International Aims and scope Submit manuscript

Abstract

We aimed to evaluate the relation between the severity of carpal tunnel syndrome and metabolic syndrome. One hundred and fifty patients who had a clinical and electrophysiologically confirmed diagnosis of carpal tunnel syndrome (CTS), were included in this study. The patients were divided into two groups (with or without metabolic syndrome) according to the criteria of National Cholesterol Education Program. Eighty one (73.5 %) of the patients with CTS had metabolic syndrome. The patients with metabolic syndrome the severity of CTS was found 22.2 % had mild CTS, 56.8 % had moderate CTS, and 21 % had severe CTS. The patients without metabolic syndrome the severity of CTS was found 44.9 % had mild CTS, 40.6 % had moderate CTS, and 14.5 % had severe CTS. The severity of CTS between both groups was found to be statistically significant (p = 0.0009). While a correlation was found between the severity of CTS and high level of LDL with the presence of metabolic syndrome (correlation coefficient 0.209). In conclusion metabolic syndrome that appears to be a risk factor for CTS. At the same time, the presence of metabolic syndrome increases the severity of the disease.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Boulton AJ, Malik RA, Arezzo JC, Sosenko JM (2004) Diabetic somatic neuropathies. Diabetes Care 27(6):1458–1486

    Article  PubMed  Google Scholar 

  2. Preston DC, Shapiro BE (2005) Electromyography and neuromuscular disorders. Clinical-electrophysiologic correlations. In: Preston DC, Shapiro BE (eds) Median neuropathy at the wrist, 2nd edn. Elsevier, Philadelphia, pp 255–281

    Google Scholar 

  3. Balcı K, Utku U (2007) Carpal tunnel syndrome and metabolic syndrome. Acta Neurol Scand 116:113–117

    PubMed  Google Scholar 

  4. American Academy of Neurology (1993) Practice parameter for carpal tunnel syndrome. Report of Quality Standards Subcommittee of the American Academy of Neurology. Neurology 43:2406–2409

    Article  Google Scholar 

  5. Grant RW, Meigs JB (2005) Management of the metabolic syndrome. Panminerva Med.üğ 47(4):219–228

    CAS  Google Scholar 

  6. Bloomgarden ZT (2003) American Association of Clinical Endocrinologists (AACE) consensus conference on the insulin resistance syndrome:25–26 August 2002, Washington, DC. Diabetes Care 26:1297–1303

    Article  PubMed  Google Scholar 

  7. Padua L, LoMonaco M, Gregori B, Valente EM, Padua R, Tonali P (1997) Neurophysiological classification and sensitivity in 500 carpal tunnel syndrome. Acta Neurol Scand 96(4):211–217

    Article  PubMed  CAS  Google Scholar 

  8. Bland JP (2007) Carpal tunnel syndrome. BMJ 335:343–346

    Article  PubMed  Google Scholar 

  9. De Krom MC, Knipschild PG, Kester AD, Thijs CT, Boekkooi PF, Spaans F (1992) Carpal tunnel syndrome: prevalence in the general population. J Clin Epidemiol 45(4):373–376

    Article  PubMed  Google Scholar 

  10. Lewis C, Mauffrey C, Newman S, Lambert A, Hull P (2010) Current concepts in carpal tunnel syndrome: a review of the literature. Eur J Orthop Surg Traumatol 20:445–452

    Article  Google Scholar 

  11. MacDermid JC, Wessel J (2004) Clinical diagnosis of carpal tunnel syndrome: a systematic review. J Hand Ther 17(2):309–319

    Article  PubMed  Google Scholar 

  12. Kaymak B, Ozçakar L, Cetin A, Candan Cetin M, Akinci A, Hasçelik Z (2008) A comparison of the benefits of sonography and electrophysiologic measurements as predictors of symptom severity and functional status in patients with carpal tunnel syndrome. Arch Phys Med Rehabil 89(4):743–748

    Article  PubMed  Google Scholar 

  13. Deryani E, Aki S, Muslumanoglu L, Rozanes I (2003) MR imaging and electrophysiological evaluation in carpal tunnel syndrome. Yonsei Med J 44(1):27–32

    PubMed  Google Scholar 

  14. Becker J, Nora DB, Gomes I, Stringari FF, Seitensus R, Panosso JS, Ehlers JC (2002) An evaluation of gender, obesity, age and diabetes mellitus as risk factors for carpal tunnel syndrome. Clin Neurophysiol 113(9):1429–1434

    Article  PubMed  Google Scholar 

  15. Hooper MM (2006) Tending to the musculoskeletal problems of obesity. Clevel Clin J Med 73(9):839–845

    Article  Google Scholar 

  16. Nordstrom DL, Vierkant RA, DeStefano F, Layde PM (1997) Risk factors for carpal tunnel syndrome in a general population. Occup Environ Med 54(10):734–740

    Article  PubMed  CAS  Google Scholar 

  17. Werner RA, Albers JW, Franzblau A, Armstrong TJ (1994) The relationship between body mass index and the diagnosis of carpal tunnel syndrome. Muscle Nerve 17(6):632–636

    Article  PubMed  CAS  Google Scholar 

  18. Becker J, Nora DB, Gomes I, Stringari FF, Seitensus R, Panosso JS, Ehlers JC (2002) An evaluation of gender, obesity, age and diabetes mellitus as risk factors for carpal tunnel syndrome. Clin Neurophysiol 113(9):1429–1434

    Article  PubMed  Google Scholar 

  19. Oğuz A, Temizhan A, Abaci A, Kozan O, Erol C, Ongen Z, Celik S (2008) Obesity and abdominal obesity; an alarming challenge for cardio-metabolic risk in Turkish adults. Anadolu Kardiyol Derg 8(6):401–406

    PubMed  Google Scholar 

  20. Geoghegan JM, Clark DI, Bainbridge LC, Smith C, Hubbard R (2004) Risk factors in carpal tunnel syndrome. J Hand Surg Br 29(4):315–320

    Article  PubMed  CAS  Google Scholar 

  21. Perkins BA, Olaleve D, Bril V (2002) Carpal tunnel syndrome in patients with diabetic polyneuropathy. Diabetes Care 25(3):565–569

    Article  PubMed  Google Scholar 

  22. Nakamichi K, Tachibana S (2005) Hypercholesterolemia as a risk factor for idiopathic carpal tunnel syndrome. Muscle Nerve 32(3):364–367

    Article  PubMed  Google Scholar 

  23. Satman I, Yılmaz T, Sengul A, Salman S, Salman F, Uygur S, Bastar I, Tütüncü Y, Sargın M, Dinççağ N, Karsidag K, Kalaça S, Özcan C, King H, the TURDEP Group (2002) Population-based study of diabetes and risk characteristics in Turkey: results of the Turkish diabetes epidemiology study (TURDEP). Diabetes Care 25:1551–1556

    Article  PubMed  Google Scholar 

  24. Freeland AE, Tucci MA, Barbieri RA, Angel MF, Nick TG (2002) Biochemical evaluation of serum and flexor tenosynovium in carpal tunnel syndrome. Microsurgery 22(8):378–385

    Article  PubMed  Google Scholar 

  25. Koh KK, Han SH, Quon MJ (2005) Inflammatory markers and the metabolic syndrome: insights from therapeutic interventions. J Am Coll Cardiol 46(11):1978–1985

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Burcu Önder.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Önder, B., Yalçın, E., Selçuk, B. et al. Carpal tunnel syndrome and metabolic syndrome co-occurrence. Rheumatol Int 33, 583–586 (2013). https://doi.org/10.1007/s00296-012-2417-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00296-012-2417-1

Keywords

Navigation