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Optic neuritis after infliximab therapy

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Abstract

Demyelinating diseases were described in patients receiving anti-TNF agents. Optic neuritis (ON) induced by TNF blockers was already described in 22 cases in the literature. In this article, the authors report a 53-year-old woman with refractory rheumatoid arthritis that developed neuritis optica after the fourth dose of infliximab and had a good outcome after anti-TNF withdrawal, associated with glucocorticoid treatment. In addition, the previous cases of ON induced by anti-TNF agents were reviewed.

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Acknowledgments

Carvalho JF received grants from the Federico Foundation and CNPq (300665/2009-1).

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Authors and Affiliations

  1. Rheumatology Division, Clínica de Oncologia (CLION), Rua Altino Seberto de Barros, 119, 7 andar, Salvador, Bahia, 41810-570, Brazil

    César Faillace & Jozélio Freire de Carvalho

  2. Radiology Division, Clinica de Assistência à Mulher (CAM), Salvador, Bahia, Brazil

    João Ricardo Maltez de Almeida

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  1. César Faillace
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  2. João Ricardo Maltez de Almeida
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  3. Jozélio Freire de Carvalho
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Correspondence to Jozélio Freire de Carvalho.

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Faillace, C., de Almeida, J.R.M. & de Carvalho, J.F. Optic neuritis after infliximab therapy. Rheumatol Int 33, 1101–1103 (2013). https://doi.org/10.1007/s00296-011-2316-x

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  • DOI: https://doi.org/10.1007/s00296-011-2316-x

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