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Massive intracerebral hemorrhage associated with Wegener granulomatosis

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Abstract

Wegener granulomatosis (WG) is a necrotizing granulomatous vasculitis that predominantly affects airways and kidneys. But central nervous system involvement (7–11%) is an uncommon. Massive ICH may occur in the course of WG, and this serious condition is related with high risk of mortality. Therefore, the new treatment strategies may be considered in addition to classical practices in serious organ involvement and recurrent attack. Here, we present an adult patient with WG whose disease was complicated by a massive intracerebral hemorrhage (ICH), which subsequently led to death.

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References

  1. Hoffman GS, Kerr GS, Leavitt RY, Hallahan CW, Lebovics RS, Travis WD et al (1992) Wegener granulomatosis: an analysis of 158 patients. Ann Intern Med 116:488–498

    PubMed  CAS  Google Scholar 

  2. Memet B, Rudinskaya A, Krebs T, Oelberg D (2005) Wegener granulomatosis with massive intracerebral hemorrhage. J Clin Rheumatol 11:314–318

    Article  PubMed  Google Scholar 

  3. Kishimoto M, Arakawa KC (2003) A patient with Wegener granulomatosis and intraventricular hemorrhage. J Clin Rheumatol 9:354–358

    Article  PubMed  Google Scholar 

  4. Seror R, Mahr A, Ramanoelina J, Pagnoux C, Cohen P, Guillevin L (2006) Central nervous system involvement in Wegener granulomatosis. Medicine (Baltimore) 85:54–65

    Google Scholar 

  5. Zhang W, Zhou G, Shi Q, Zhang X, Zeng XF, Zhang FC (2009) Clinical analysis of nervous system involvement in ANCA-associated systemic vasculitides. Clin Exp Rheumatol 27:65–69

    Google Scholar 

  6. Granziera C, Michel P, Rossetti AO, Lurati F, Reymond S, Bogousslavsky J (2005) Wegener granulomatosis presenting with haemorrhagic stroke in a young adult. J Neurol 252:615–616

    Article  PubMed  Google Scholar 

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The authors have not received funding for research on this article.

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Correspondence to Mevlut Ceri.

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Ceri, M., Ortabozkoyun, L., Unverdi, S. et al. Massive intracerebral hemorrhage associated with Wegener granulomatosis. Rheumatol Int 32, 1813–1814 (2012). https://doi.org/10.1007/s00296-011-1954-3

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  • DOI: https://doi.org/10.1007/s00296-011-1954-3

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