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Clinical and demographic characteristics of patients with psoriatic arthritis in northern Israel

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Abstract

Disease patterns and manifestations may vary among different populations and change over time. The purpose of our study was to define the demographic, clinical, roentgenologic, and laboratory findings in a recent cohort of psoriatic arthritis patients followed up in rheumatology clinics in northern Israel. We conducted a cross-sectional study of 149 psoriatic arthritis patients. Demographic, clinical, laboratory, and radiological data, with emphasis on the pattern of arthritis, treatment regimens, and co-morbidities were obtained from patient interviews and rheumatology file reviews. The mean age of our patients was 58.2, with a female preponderance (57.3%). Skin involvement preceded the arthritis or was diagnosed simultaneously in 90.1% of cases. The most common joint involvement was an RA-like arthritis (49.7% of the patients) correlating positively with age, female gender, and disease duration. Dactylitis and nail involvement were observed in 33.6 and 36.2% of the patients, respectively. Radiographic bone erosions were noted in a third of the patients, correlating with DIP and RA-like arthritis patterns. Most patients were treated with methotrexate (73.8%) and a combination therapy (41.4%). An increased incidence of hypertension, hyperlipidemia, and diabetes mellitus was noted in our cohort compared to the general Israeli population. Our survey, the first of its kind conducted in Israel, noted a relative increase in the polyarticular manifestation of PsA and a decrease in spondyloarthropathy, compared to historic series, with more aggressive disease found in women above the age of sixty. These findings are in line with recent surveys.

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Authors and Affiliations

  1. Department of Internal Medicine, Carmel Medical Center, 7 Michal Street, Haifa, 34362, Israel

    Devy Zisman, Lihi Eder, Arie Laor & Haim Bitterman

  2. Rheumatology Clinic, Lin Medical Center, Clalit Health Service, Haifa, Israel

    Devy Zisman, Lihi Eder, Muna Elias & Joy Feld

  3. Department of Rheumatology, Bnai Zion Medical Center, Haifa, Israel

    Muna Elias, Michael Rozenbaum, Joy Feld, Doron Rimar & Itzhak Rosner

  4. Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel

    Haim Bitterman & Itzhak Rosner

Authors
  1. Devy Zisman
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  2. Lihi Eder
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  3. Muna Elias
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  4. Arie Laor
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  5. Haim Bitterman
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  6. Michael Rozenbaum
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  7. Joy Feld
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  8. Doron Rimar
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  9. Itzhak Rosner
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Corresponding author

Correspondence to Devy Zisman.

Additional information

D. Zisman and L. Eder contributed equally to this article.

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Zisman, D., Eder, L., Elias, M. et al. Clinical and demographic characteristics of patients with psoriatic arthritis in northern Israel. Rheumatol Int 32, 595–600 (2012). https://doi.org/10.1007/s00296-010-1673-1

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  • DOI: https://doi.org/10.1007/s00296-010-1673-1

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