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Antiphospholipid syndrome: a predisposing factor for early onset HELLP syndrome

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Abstract

Hemolysis elevated liver enzymes low platelets syndrome (HELLP) is a relatively rare pregnancy-related thrombotic microangiopathic disorder, usually observed during the third trimester. Its incidence seems to be increased in patients with antiphospholipid syndrome (APS). In this report, we describe a 33-year-old pregnant woman with previously known primary APS who developed early onset HELLP syndrome during the 15th week of gestation. We also review the literature about this interesting relationship between APS and HELLP.

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Authors and Affiliations

  1. 2nd Department of Internal Medicine, Propaudeutic, University of Athens, “ATTIKON” General University Hospital, Rimini-1, Haidari, 124 62, Athens, Greece

    Panagiotis Tsirigotis, Vassiliki Pappa, Konstantinos Girkas, Vassiliki Giannopoulou, Sotirios Papageorgiou & John Dervenoulas

  2. Department of Transfusion Service, University of Athens, “ATTIKON” General University Hospital, Athens, Greece

    George Mantzios & Anthi Travlou

  3. Third Department of Obstetrics and Gynecology, University of Athens, “ATTIKON” General University Hospital, Athens, Greece

    George Salamalekis & Angellos Koutras

  4. 2nd Department of Radiology, University of Athens, “ATTIKON” General University Hospital, Athens, Greece

    Konstantina Spirou & Alexia Balanika

Authors
  1. Panagiotis Tsirigotis
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  2. George Mantzios
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  3. Vassiliki Pappa
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  7. Vassiliki Giannopoulou
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Correspondence to Panagiotis Tsirigotis.

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Tsirigotis, P., Mantzios, G., Pappa, V. et al. Antiphospholipid syndrome: a predisposing factor for early onset HELLP syndrome. Rheumatol Int 28, 171–174 (2007). https://doi.org/10.1007/s00296-007-0386-6

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  • DOI: https://doi.org/10.1007/s00296-007-0386-6

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