Skip to main content

Advertisement

SpringerLink
Log in

Reversible T-large granular lymphocyte expansion and neutropenia associated with adalimumab therapy

  • Case Report
  • Published:
Rheumatology International Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Olsen NJ, Stein CM (2004) New drugs for rheumatoid arthritis. N Engl J Med 350:2167–2179

    Article  PubMed  CAS  Google Scholar 

  2. Vidal F, Fontova R, Richart C (2003) Severe neutropenia and thrombocytopenia associated with infliximab. An Int Med 139:238–239

    Google Scholar 

  3. Favalli EG, Varenna M, Sinigaglia L (2005) Drug-induced agranulocytosis during treatment with infliximab in enteropathic spondyloarthropathy. Clin Exp Rheumatol 23:247–250

    PubMed  CAS  Google Scholar 

  4. Bathon JM, Martin RW, Fleischmann RM, Tesser JR, Schiff MH, Keystone EC, Genovese MC, Wasko MC, Moreland LW, Weaver AL, Markenson J, Finck BK (2000) A comparison of etanercept and methotrexate in patients with early rheumatoid arthritis. N Engl J Med 343:1586–1593

    Article  PubMed  CAS  Google Scholar 

  5. Lamy T, Loughran TP (2003) Clinical features of large granular lymphocyte leukemia. Sem Hem 40:185–195

    Article  Google Scholar 

  6. Liu JH, Wei S, Lamy T, Epling-Burnette PK, Starkebaum G, Djeu JY, Loughran TP (2000) Chronic neutropenia mediated by fas ligand. Blood 95:3219–3222

    PubMed  CAS  Google Scholar 

  7. Coacley G, Iqbal M, Brooks D, Panayi GS, Lanchbury JS (2000) CD8 + CD57 + T cells suppress neutrophil development in vitro: implications for the neutropenia of Felty’s and large granular lymphocyte syndromes. Arthritis Rheum 43:834–843

    Article  Google Scholar 

  8. Keystone EC (2001) Tumor necrosis factor-alpha blockade in the treatment of rheumatoid arthritis. Rheum Dis Clin North Am 27:427–443

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Rheumatology Unit, 1st Department of Internal Medicine, AHEPA University Hospital, Thessaloniki, Greece

    Athina Theodoridou & Lucas Settas

  2. Laboratory of Hematology, “Theageneion” Cancer Hospital, Al. Simeonidi 2, 54007, Thessaloniki, Greece

    Charalambos Kartsios, Efthalia Yiannaki & Dimitra Markala

Authors
  1. Athina Theodoridou
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Charalambos Kartsios
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Efthalia Yiannaki
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Dimitra Markala
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Lucas Settas
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Charalambos Kartsios.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Theodoridou, A., Kartsios, C., Yiannaki, E. et al. Reversible T-large granular lymphocyte expansion and neutropenia associated with adalimumab therapy. Rheumatol Int 27, 201–202 (2006). https://doi.org/10.1007/s00296-006-0187-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00296-006-0187-3

Keywords

Search

Navigation