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Varicella glomerulonephritis mimicking microscopic polyangiitis

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Abstract

Varicella in childhood is usually a self-limiting illness with few complications. Varicella nephritis is an uncommon entity and seen mostly in immunocompromized individuals. We report a 14-year-old boy with juvenile rheumatoid arthritis who developed varicella nephritis and in whom the renal manifestations preceded the skin lesions by 1 week. This is an extremely unusual occurrence, and only one case has been described before. Such a presentation can mimic the clinical features of microscopic polyangiitis.

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References

  1. Fleisher G, Henry W, McSorley M et al (1981) Life threatening complications of varicella. Am J Dis Child 135:896–989

    Google Scholar 

  2. Jackson MA, Burry VF, Olson LC (1992) Complications of varicella requiring hospitalization in previously healthy children. Pediatr Infect Dis J 11:441–544

    CAS  PubMed  Google Scholar 

  3. Bonkovsky HL, Mehta S (2001) Hepatitis C: a review and update. J Am Acad Dermatol 44:159–182

    Article  CAS  PubMed  Google Scholar 

  4. D’Amico G, Fornasieri A (1995) Cryoglobulinemic glomerulonephritis: a membrano-proliferative glomerulonephritis induced by hepatitis C virus. Am J Kidney Dis 25:361–369

    CAS  Google Scholar 

  5. Garini G, Allegri L, Carnevali L et al (2001) Interferon-α in combination with ribavirin as initial treatment for hepatitis C virus-associated cryoglobulinemic membranoproliferative glomerulonephritis. Am J Kidney Dis 38:E35

    CAS  PubMed  Google Scholar 

  6. Bullowa JGM, Wishik SM (1935) Complications of varicella. Am J Dis Child 49:923

    Google Scholar 

  7. Prebuld SR, Orenstein WA, Bart KJ (1984) Varicella: clinical manifestations, epidemiology and health impact in children. Pediatr Infect Dis J 3:505–509

    Google Scholar 

  8. Leibold C, Von Kries R, Lang R et al (2001) Severe complications of varicella in previously healthy children in Germany: a 1-year survey. Pediatrics 108:E79

    PubMed  Google Scholar 

  9. Pedersen FK, Petersen EA (1975) Varicella followed by glomerulonephritis. Treatment with corticosteroids and azathioprine resulting in recurrence of varicella. Acta Paediatr Scand 64:886–890

    CAS  PubMed  Google Scholar 

  10. Singhal PC, Chugh KS, Muthusethupathi MA (1977) Rapidly progressive glomerulonephritis associated with varicella infection. J Pediatrics 91:680–681

    CAS  Google Scholar 

  11. Fuhrer JA, Mihatsch MJ, Streuli RA (1990) Poststreptococcal glomerulonephritis flare-up in a patient with varicella infection. Klin Wochenschr 68:1198–1201

    CAS  PubMed  Google Scholar 

  12. Phuah HK, Chong CY, Lim KW, Cheng HK (1998) Complicated varicella zoster infection in 8 pediatric patients and review of literature. Singapore Med J 39:115–120

    CAS  PubMed  Google Scholar 

  13. Moros Pena M, Labay Matias M, de Miguel Pardo C et al (2001) Arterial hypertension, hematuria and renal involvement before chicken pox [Spanish]. An Esp Pediatr 55:73–75

    PubMed  Google Scholar 

  14. Whitley RJ (1984) Varicella zoster infections. In: Galusso GJ, Megan TC, Buchanan RA (eds) Antiviral agents and viral diseases of man. Raven, New York, pp 517–541

  15. Feldman SF, Hughes WT, Daniel CB (1975) Varicella in children with cancer: seventy-seven cases. Pediatrics 56:388–397

    CAS  PubMed  Google Scholar 

  16. Prebuld SR (1981) Age-specific risks of varicella complications. Pediatrics 68:14–17

    PubMed  Google Scholar 

  17. Gucuyer K, Citak EC, Elli M et al (2002) Complications of varicella zoster. Indian J Pediatr 69:195–196

    PubMed  Google Scholar 

  18. El-Reshaid, Kapoor MM, El-Reshaid W et al (1997) The spectrum of renal disease associated with microscopic polyangiitis and classic polyarteritis nodosa in Kuwait. Nephrol Dial Transplant 12:1874–1882

    Article  CAS  PubMed  Google Scholar 

  19. Minokowitz S, Wenk R, Friedman E et al (1968) Acute glomerulonephritis associated with varicella infection. Am J Med 44:489–492

    PubMed  Google Scholar 

  20. Ljutić D, Glavina M (1995) Tubulointerstitial nephritis with uveitis syndrome following varicella zoster reactivation. Nephron 71:485–486

    PubMed  Google Scholar 

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Correspondence to Surjit Singh.

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Dass, R., Singh, S., Kumar, V. et al. Varicella glomerulonephritis mimicking microscopic polyangiitis. Rheumatol Int 24, 362–364 (2004). https://doi.org/10.1007/s00296-003-0429-6

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  • DOI: https://doi.org/10.1007/s00296-003-0429-6

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