Skip to main content
Log in

Neue TNM-Klassifikation maligner Lungentumoren

New TNM classification of malignant lung tumours

  • Schwerpunkt
  • Published:
Der Pathologe Aims and scope Submit manuscript

Zusammenfassung

Das Staging-System für Lungentumoren soll ab der 7. Auflage für nichtkleinzellige und kleinzellige Lungenkarzinome angewendet werden, aber auch für Karzinoidtumoren (typische und atypische Karzinoide). Die T-Kategorien sind neu definiert worden, mit einer Unterteilung von T1 in T1a (≤2 cm im größten Durchmesser) und T1b (>2 bis 3 cm im größten Durchmesser) und von T2 in T2a (>3 bis 5 cm) und T2b (>5 bis 7 cm). Tumoren über 7 cm werden als T3 klassifiziert. Multiple Tumorknoten im selben Lungenlappen werden von T4 in T3 reklassifiziert und multiple Tumorknoten in derselben Lunge, aber in verschiedenen Lappen von M1 nach T4. Die M-Kategorien wurden neu definiert: M1 wurde in M1a und M1b unterteilt. Maligne Pleura- oder Perikardergüsse wurden von T4 nach M1a reklassifiziert. Tumorknoten in der kontralateralen Lunge werden als M1a klassifiziert. Fernmetastasen werden als M1b eingestuft.

Abstract

The staging system for lung tumours is now recommended for the classification of both non-small-cell and small-cell lung cancer as well as for carcinoid tumours of the lung. The T classifications have been redefined: T1 has been subclassified as T1a (≤2 cm in size) and T1b (>2–3 cm in size). T2 has been subclassified as T2a (>3–5 cm in size) and T2b (>5–7 cm in size). T2 (>7 cm in size) has been reclassified as T3. Multiple tumour nodules in the same lobe have been reclassified from T4 to T3. Multiple tumour nodules in the same lung but a different lobe have been reclassified from M1 to T4. No changes have been made in the N classification. The M classification has been redefined: M1 has been subdivided into M1a and M1b. Malignant pleural and pericardial effusions have been reclassified from T4 to M1a. Separate tumour nodules in the contralateral lung have been reclassified from T4 to M1a. M1b designates distant metastasis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abb. 1
Abb. 2
Abb. 3

Literatur

  1. UICC (International Union Against Cancer) (1997) TNM classification of malignant tumors. Sobin LH, Wittekind C (Hrsg) 5. Aufl. Springer, New York (deutsche Übersetzung: TNM-Klassifikation maligner Tumoren. 5. Aufl. Herausgegeben und übersetzt von Wittekind C, Wagner G. Springer, Berlin Heidelberg New York)

  2. UICC (International Union Against Cancer) (2002) TNM classification of malignant tumors. Sobin LH, Wittekind C (Hrsg) 6. Aufl. Wiley, New York (Deutsche Übersetzung: TNM-Klassifikation maligner Tumoren. 6. Aufl. Herausgegeben und übersetzt von Wittekind C, Bootz F, Meyer HJ. Springer, Berlin Heidelberg New York)

  3. UICC (International Union Against Cancer) (2010) TNM classification of malignant tumors. Sobin LH, Wittekind C (Hrsg) 7. Aufl. Wiley, New York (deutsche Übersetzung: TNM-Klassifikation maligner Tumoren. 7. Aufl. Herausgegeben und übersetzt von Wittekind C, Bootz F, Meyer HJ. Springer, Berlin Heidelberg New York)

  4. Travis WD (2009) Reporting lung cancer pathology specimens. Impact of the anticipated 7th Edition TNM classification based on recommendations of the IASLC Staging Committee. Histopathology 54:3–11

    Article  PubMed  Google Scholar 

  5. Rami-Porta R, Ball D, Crowley J et al (2007) The IASLC Lung Cancer Staging Project: proposals for the revision of the T descriptors in the forthcoming (seventh) edition of the TNM classification for lung cancer. J Thorac Oncol 2:593–602

    Article  PubMed  Google Scholar 

  6. Fisseler-Eckhoff A (2009) New TNM classification of malignant lung tumors 2009 from a pathology perspective. Pathologe 30 (Suppl 2):193–199

    Article  PubMed  Google Scholar 

  7. Rusch VW, Crowley J, Giroux DJ et al (2007) The IASLC Lung Cancer Staging Project: proposals for the revision of the N descriptors in the forthcoming seventh edition of the TNM classification for lung cancer. J Thorac Oncol 2:603–612

    Article  PubMed  Google Scholar 

  8. Rami-Porta R, Crowley JJ, Goldstraw P (2009) The revised TNM staging system for lung cancer. Ann Thorac Cardiovasc Surg 15:4–9

    PubMed  Google Scholar 

  9. Goldstraw P, Crowley JJ (2006) The International Association for the Study of Lung Cancer international staging project on lung cancer. J Thorac Oncol 281–286

  10. Goldstraw P, Crowley J, Chansky K et al (2007) The IASLC Lung Cancer Staging project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours. J Thorac Oncol 2:706–714

    Article  PubMed  Google Scholar 

  11. Kang JH, Kim KD, Chung KY (2003) Prognostic value of visceral pleura invasion in non-small cell lung cancer. Eur J Cardiothorac Surg 23:865–869

    Article  PubMed  Google Scholar 

  12. Manach D, Riquet M, Medioni J et al (2001) Visceral pleura invasion by non-small cell lung cancer: an underrated bad prognostic factor. Ann Thorac Surg 71:1088–1093

    Article  CAS  Google Scholar 

  13. Osaki T, Nagashima A, Yoshimatsu T et al (2004) Visceral pleural involvement in non small cell lung cancer: prognostic significance. Ann Thorac Surg 77:1769–1773

    Article  PubMed  Google Scholar 

  14. Shimizu K, Yoshida J, Nagai K et al (2004) Visceral pleural invasion classification in non-small cell lung cancer: a proposal on the basis of outcome assessment. J Thorac Cardiovasc Surg 127:1574–1578

    Article  PubMed  Google Scholar 

  15. Shimizu K, Yoshida J, Nagai K et al (2005) Visceral pleural invasion is an invasive and aggressive indicator of non-small cell lung cancer. J Thorac Cardiovasc Surg 130:160–165

    Article  PubMed  Google Scholar 

  16. Battafarano RJ, Meyers BF, Guthrie TJ et al (2002) Surgical resection of multifocal non-small cell lung cancer is associated with prolonged survival. Ann Thorac Surg 74:988–993

    Article  PubMed  Google Scholar 

  17. Roberts PF, Straznicka M, Lara PN et al (2003) Resection of multifocal non-small cell lung cancer when the bronchioloalveolar subtype is involved. J Thorac Cardiovasc Surg 126:1597–1602

    Article  PubMed  Google Scholar 

  18. Postmus PE, Brambilla E, Chansky K et al (2007) The IASLC Lung Cancer Staging project: proposals for revision of the M descriptors in the forthcoming (seventh) edition of the TNM classification of lung cancer. J Thorac Oncol 2:686–693

    Article  PubMed  Google Scholar 

  19. Travis WD, Giroux DJ, Chansky K et al (2008) Proposals for the inclusion of bronchopulmonary carcinoid tumor in the forthcoming (seventh) edition of the TNM classification for lung cancer. J Thorac Oncol 3:1213–1223

    Article  PubMed  Google Scholar 

  20. Shepherd FA, Ginsberg RJ, Feld R et al (1991) Surgical treatment for limited small-cell lung cancer. The University of Toronto Lung Oncology Group experience. J Thorac Cardiovasc Surg 101:385–393

    CAS  PubMed  Google Scholar 

  21. Waddell TK, Shepherd FA (2004) Should aggressive surgery ever be part of the management of small cell lung cancer? Thorac Surg Clin 14:271–281

    Article  PubMed  Google Scholar 

  22. Shepherd FA, Crowley J, Van HP et al (2007) The International Association for the Study of Lung Cancer lung cancer staging project: proposals regarding the clinical staging of small cell lung cancer in the forthcoming (seventh) edition of he tumor, node, metastasis classification for lung cancer. J Thorac Oncol 2:1067–1077

    Article  PubMed  Google Scholar 

Download references

Interessenkonflikt

Der korrespondierende Autor gibt an, dass kein Interessenkonflikt besteht.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to J. Wohlschläger.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Wohlschläger, J., Wittekind, C. & Theegarten, D. Neue TNM-Klassifikation maligner Lungentumoren. Pathologe 31, 355–360 (2010). https://doi.org/10.1007/s00292-010-1303-4

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00292-010-1303-4

Schlüsselwörter

Keywords

Navigation