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Mathematical Model for Rhythmic Protoplasmic Movement in the True Slime Mold

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Abstract

The plasmodium of the true slime mold Physarum polycephalum is a large amoeboid organism that displays “smart” behavior such as chemotaxis and the ability to solve mazes and geometrical puzzles. These amoeboid behaviors are based on the dynamics of the viscoelastic protoplasm and its biochemical rhythms. By incorporating both these aspects, we constructed a mathematical model for the dynamics of the organism as a first step towards understanding the relation between protoplasmic movement and its unusual abilities. We tested the validity of the model by comparing it with physiological observation. Our model reproduces fundamental characteristics of the spatio-temporal pattern of the rhythmic movement: (1) the antiphase oscillation between frontal tip and rear when the front is freely extending; (2) the asynchronous oscillation pattern when the front is not freely extending; and (3) the formation of protoplasmic mounds over a longer time scale. Both our model and physiological observation suggest that cell stiffness plays a primary role in plasmodial behaviors, in contrast to the conventional theory of coupled oscillator systems.

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Authors and Affiliations

  1. Department of Mathematical and Life Sciences, Hiroshima University, Higashi Hiroshima, 739-8526, Japan

    Ryo Kobayashi & Atsushi Tero

  2. Research Institute for Electronic Science, Hokkaido University, Sapporo, 060-0812, Japan

    Toshiyuki Nakagaki

  3. Creative Research Initiative “SOUSEI”, Hokkaido University, Sapporo, 001-0821, Japan

    Toshiyuki Nakagaki

Authors
  1. Ryo Kobayashi
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  2. Atsushi Tero
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  3. Toshiyuki Nakagaki
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Correspondence to Ryo Kobayashi.

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Kobayashi, R., Tero, A. & Nakagaki, T. Mathematical Model for Rhythmic Protoplasmic Movement in the True Slime Mold. J. Math. Biol. 53, 273–286 (2006). https://doi.org/10.1007/s00285-006-0007-0

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  • DOI: https://doi.org/10.1007/s00285-006-0007-0

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