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A delay recruitment model of the cardiovascular control system

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Abstract

We develop a nonlinear delay-differential equation for the human cardiovascular control system, and use it to explore blood pressure and heart rate variability under short-term baroreflex control. The model incorporates an intrinsically stable heart rate in the absence of nervous control, and allows us to compare the baroreflex influence on heart rate and peripheral resistance. Analytical simplifications of the model allow a general investigation of the rôles played by gain and delay, and the effects of ageing.

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Authors and Affiliations

  1. Mathematical Institute, University of Oxford, 24–29 St. Giles', OX1 3LB, United Kingdom

    A.C. Fowler

  2. Division of Applied Mathematics, Korea Advanced Institute of Science and Technology, Taejon, South Korea

    M.J. McGuinness

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  1. A.C. Fowler
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  2. M.J. McGuinness
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Correspondence to M.J. McGuinness.

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Fowler, A., McGuinness, M. A delay recruitment model of the cardiovascular control system. J. Math. Biol. 51, 508–526 (2005). https://doi.org/10.1007/s00285-005-0339-1

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  • DOI: https://doi.org/10.1007/s00285-005-0339-1

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