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Multilocus Sequence Types of Campylobacter jejuni Isolates from Different Sources in Eastern China

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Abstract

Campylobacter jejuni is a major food-borne pathogen that causes human gastroenteritis in many developed countries. In our study, we applied multilocus sequence typing (MLST) technology to 167 C. jejuni isolates from diverse sources in Eastern China to examine their genetic diversity. MLST defined 94 sequence types (STs) belonging to 18 clonal complexes (CCs). Forty-five STs from 60 isolates (36 %) and 22 alleles have not been previously documented in an international database. One hundred and two isolates, accounting for 61.1 % of all isolates, belonged to eight clonal complexes. The eight major CCs were also the most common complexes from different sources. The most common ST type of isolates from human and food was ST-353. The dominant ST type in chicken and foods was ST-354. Among 21 STs that contained two or more different sources isolates, 15 STs contained human isolates and isolates from other sources, suggesting that potentially pathogenic strains are not restricted to specific lineages.

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Acknowledgments

This study was supported by the National Natural Science Foundation of China Grant (31372449), National Key Technology R&D Program (2014BAD13B02), and a Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD).

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Authors and Affiliations

  1. Jiangsu Key Lab of Zoonosis, Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, 88 South Daxue Road, Yangzhou, 225009, Jiangsu, China

    Gong Zhang, Xiaoyan Zhang, Yuanqing Hu, Xin-an Jiao & Jinlin Huang

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  1. Gong Zhang
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  2. Xiaoyan Zhang
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  3. Yuanqing Hu
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  4. Xin-an Jiao
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  5. Jinlin Huang
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Correspondence to Jinlin Huang.

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Gong Zhang and Xiaoyan Zhang were the joint first authors.

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Zhang, G., Zhang, X., Hu, Y. et al. Multilocus Sequence Types of Campylobacter jejuni Isolates from Different Sources in Eastern China. Curr Microbiol 71, 341–346 (2015). https://doi.org/10.1007/s00284-015-0853-3

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  • DOI: https://doi.org/10.1007/s00284-015-0853-3

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