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MicroRNAs: a new key in lung cancer

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Abstract

Lung cancer as a malignance has been killing numerous patients around the world annually, and small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC) are the two major types, the later accounting for nearly 80 % of lung cancer. There are multiple causes for lung cancer, and more researches have been carried out to prevent, anticipate, and diagnose the cancer. MicroRNAs (miRNAs) are small non-coding RNA molecules capable of regulating expression of over 50 % of protein-coding genes. The RNA molecules are stable in tissues and blood, so it can tend to be a biomarker in anti-lung cancer. Here, this is a review on the roles of miRNAs for possible ways to prevent lung cancer in clinical trials.

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Authors and Affiliations

  1. Department of Natural Medicine, School of Pharmacy, Fourth Military Medical University, 169 West Changle Road, Xi’an, 710032, People’s Republic of China

    Yunlong Zhang, Qian Yang & Siwang Wang

  2. Collaborative Innovation Center for Chinese Medicine in Qinba Mountains, 169 West Changle Road, Xi’an, 710032, People’s Republic of China

    Yunlong Zhang, Qian Yang & Siwang Wang

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  2. Qian Yang
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Correspondence to Siwang Wang.

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Zhang, Y., Yang, Q. & Wang, S. MicroRNAs: a new key in lung cancer. Cancer Chemother Pharmacol 74, 1105–1111 (2014). https://doi.org/10.1007/s00280-014-2559-9

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