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Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): report of a patient with isolated renotesticular involvement after cure of non-Hodgkin's lymphoma

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Abstract

 Sinus histiocytosis with massive lymphadenopathy (SHML) – Rosai-Dorfman disease – is a rare but well-defined benign histiocytic proliferative disorder. We report an unusual patient, cured of non-Hodgkin's lymphoma, who presented 12 years later with renotesticular SHML associated with IgA monoclonal gammopathy, but without any evidence of relapsed lymphoma. The genitourinary manifestations of this disorder with massive lymphadenopathy and its rare association with malignant lymphoma are reviewed.

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Authors and Affiliations

  1. Lymphoma and Leukemia Unit, Department of Hematology, Hadassah University Hospital, P. O. B. 12000, Jerusaelm IL-91120, Israel, , , , , , IL

    I. S. Lossos, V. Bogomolski-Yahalom & A. Polliack

  2. Lymphoma and Leukemia Unit, Department of Pathology, Hadassah University Medical Center, Jerusalem, Israel, , , , , , IL

    E. Okon & N. Ron

Authors
  1. I. S. Lossos
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  2. E. Okon
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  3. V. Bogomolski-Yahalom
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  4. N. Ron
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  5. A. Polliack
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Received: 4 July 1996 / Accepted: 25 September 1996

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Lossos, I., Okon, E., Bogomolski-Yahalom, V. et al. Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): report of a patient with isolated renotesticular involvement after cure of non-Hodgkin's lymphoma. Ann Hematol 74, 41–44 (1997). https://doi.org/10.1007/s002770050254

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  • DOI: https://doi.org/10.1007/s002770050254

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