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High prevalence of hepatitis B virus infection in patients with aggressive B cell non-Hodgkin’s lymphoma in China

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Abstract

We retrospectively analyzed a large study to investigate the association of hepatitis B virus (HBV) with aggressive B cell non-Hodgkin’s lymphoma (aggressive B-NHL) in China, where HBV is endemic. HBV was present in 39 aggressive B-NHL patients (10.46%), 13 indolent B-NHL patients (5.09%), 12 multiple myeloma (MM) patients (3.67%), and 5 solitary plasmacytoma (SP) patients (6.67%). HBV infection was significantly associated with increased risks for aggressive B-NHL (P < 0.01). HBV seems to have a very important role in the pathogenesis of aggressive B-NHL in China.

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Authors and Affiliations

  1. Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin’s Clinical Research Center for Cancer, Tianjin, 300060, China

    Chaoyu Wang, Bing Xia, Qiaoyang Ning, Haifeng Zhao, Hongliang Yang, Zhigang Zhao, Xiaofang Wang, Yafei Wang, Yong Yu & Yizhuo Zhang

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  1. Chaoyu Wang
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  2. Bing Xia
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  3. Qiaoyang Ning
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  4. Haifeng Zhao
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Correspondence to Yizhuo Zhang.

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Wang, C., Xia, B., Ning, Q. et al. High prevalence of hepatitis B virus infection in patients with aggressive B cell non-Hodgkin’s lymphoma in China. Ann Hematol 97, 453–457 (2018). https://doi.org/10.1007/s00277-017-3188-2

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  • DOI: https://doi.org/10.1007/s00277-017-3188-2

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