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Decitabine in patients with relapsed acute myeloid leukemia (AML) after allogeneic stem cell transplantation (allo-SCT)

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References

  1. Kumar L (1994) Leukemia: management of relapse after allogeneic bone marrow transplantation. J Clin Oncol 12:1710–1717

    PubMed  CAS  Google Scholar 

  2. Graef T, Kuendgen A, Fenk R, Zohren F, Haas R, Kobbe G (2007) Successful treatment of relapsed AML after allogeneic stem cell transplantation with azacitidine. Leuk Res 31:257–259

    Article  PubMed  CAS  Google Scholar 

  3. Jabbour E, Giralt S, Kantarjian H, Garcia-Manero G, Jagasia M, Kebriaei P et al (2009) Low-dose azacitidine after allogeneic stem cell transplantation for acute leukemia. Cancer 115(9):1899–1905

    Article  PubMed  CAS  Google Scholar 

  4. de Lima M, Giralt S, Thall PF, de Padua Silva L, Jones RB, Komanduri K et al (2010) Maintenance therapy with low-dose azacitidine after allogeneic hematopoietic stem cell transplantation for recurrent acute myelogenous leukemia or myelodysplastic syndrome: a dose and schedule finding study. Cancer 116(23):5420–5431

    Article  PubMed  Google Scholar 

  5. Czibere A, Bruns I, Kroger N, Platzbecker U, Lind J, Zohren F et al (2010) 5-Azacytidine for the treatment of patients with acute myeloid leukemia or myelodysplastic syndrome who relapse after allo-SCT: a retrospective analysis. Bone Marrow Transplant 45(5):872–876

    Article  PubMed  CAS  Google Scholar 

  6. Platzbecker U, Wermke M, Radke J, Oelsclaegel U, Seltmann F, Kiani A et al (2012) Azacytidine for treatment of imminent relapse in MDS or AML patients after allogeneic HSCT: results of the RELAZA trial. Leukemia 36:381–389

    Article  Google Scholar 

  7. Kantarjian HM, Thomas XG, Dmoszynska A, Wierzbowska A, Mazur G, Mayer J et al (2012) Multicenter, randomized, open-label, phase III trial of decitabine versus patient choice, with physician advice, of either supportive care or low-dose cytarabine for the treatment of older patients with newly diagnosed acute myeloid leukemia. J Clin Oncol 30:2670–26778

    Article  PubMed  CAS  Google Scholar 

  8. Ravandi F, Kantarjian H, Cohen A, Davis M, O’Brien S, Anderlini P et al (2001) Decitabine with allogeneic peripheral blood stem cell transplantation in the therapy of leukemia relapse following a prior transplant: results of a phase I study. Bone Marrow Transplant 27:1221–1225

    Article  PubMed  CAS  Google Scholar 

  9. Thomas X, Chelghoum Y, Cannas G, Elhamri M, Labussière H, Tigaud I et al (2011) Leukocytosis and circulating blasts in older adults with newly diagnosed acute myeloid leukemia: are they valuable factors for therapeutic decision-making? Clin Lymphoma Myeloma Leuk 4:342–9

    Article  Google Scholar 

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Correspondence to Siddhartha Ganguly.

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Ganguly, S., Amin, M., Divine, C. et al. Decitabine in patients with relapsed acute myeloid leukemia (AML) after allogeneic stem cell transplantation (allo-SCT). Ann Hematol 92, 549–550 (2013). https://doi.org/10.1007/s00277-012-1607-y

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  • DOI: https://doi.org/10.1007/s00277-012-1607-y

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