References
Elter T, Vehreschild JJ, Gribben J, Cornely OA, Engert A, Hallek M (2008) Management of infections in patients with chronic lymphocytic leukemia treated with alemtuzumab. Ann Hematol 88:121–132
Rosenfeld S, Follmann D, Nunez O, Young NS (2003) Antithymocyte globulin and cyclosporine for severe aplastic anemia: association between hematologic response and long-term outcome. JAMA 289:1130–1135. doi:10.1001/jama.289.9.1130
Risitano AM, Selleri C, Serio B, Marando L, Camera A, Catalano L, Scalia G, Del Vecchio L, Rotoli B (2007) Subcutaneous alemtuzumab is safe and effective for treatment of global or single-lineage immune-mediated marrow failure: a pilot study. Blood 110:1692a
Scheinberg P, Fischer SH, Li L, Nunez O, Wu CO, Sloand EM, Cohen JI, Young NS, John Barrett A (2007) Distinct EBV and CMV reactivation patterns following antibody-based immunosuppressive regimens in patients with severe aplastic anemia. Blood 109:3219–3224. doi:10.1182/blood-2006-09-045625
Nguyen DD, Cao TM, Dugan K, Starcher SA, Fechter RL, Coutre SE (2002) Cytomegalovirus viremia during Campath-1H therapy for relapsed and refractory chronic lymphocytic leukemia and prolymphocytic leukemia. Clin Lymphoma 3:105–110. doi:10.3816/CLM.2002.n.016
Laurenti L, Piccioni P, Cattani P, Cingolani A, Efremov D, Chiusolo P, Tarnani M, Fadda G, Sica S, Leone G (2004) Cytomegalovirus reactivation during alemtuzumab therapy for chronic lymphocytic leukemia: incidence and treatment with oral ganciclovir. Haematologica 89:1248–1252
Chakrabarti S, Mackinnon S, Chopra R, Kottaridis PD, Peggs K, O'Gorman P, Chakraverty R, Marshall T, Osman H, Mahendra P, Craddock C, Waldmann H, Hale G, Fegan CD, Yong K, Goldstone AH, Linch DC, Milligan DW (2002) High incidence of cytomegalovirus infection after nonmyeloablative stem cell transplantation: potential role of Campath-1H in delaying immune reconstitution. Blood 99:4357–4363. doi:10.1182/blood.V99.12.4357
Goodrich JM, Bowden RA, Fisher L, Keller C, Schoch G, Meyers JD (1993) Ganciclovir prophylaxis to prevent cytomegalovirus disease after allogeneic marrow transplant. Ann Intern Med 118:173–178
Ayala E, Greene J, Sandin R, Perkins J, Field T, Tate C, Fields KK, Goldstein S (2006) Valganciclovir is safe and effective as pre-emptive therapy for CMV infection in allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplant 37:851–856. doi:10.1038/sj.bmt.1705341
O'Brien S, Ravandi F, Riehl T, Wierda W, Huang X, Tarrand J, O'Neal B, Kantarjian H, Keating M (2008) Valganciclovir prevents cytomegalovirus reactivation in patients receiving alemtuzumab-based therapy. Blood 111:1816–1819. doi:10.1182/blood-2007-03-080010
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AMR, CS, and BR designed the study; AMR and BS performed the study; AMR analyzed the data and wrote the paper in collaboration with BR. All authors discussed and interpreted the data and revised the paper.
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Risitano, A.M., Serio, B., Selleri, C. et al. Valganciclovir as CMV reactivation prophylaxis in patients receiving alemtuzumab for marrow failure syndromes. Ann Hematol 88, 1261–1262 (2009). https://doi.org/10.1007/s00277-009-0749-z
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DOI: https://doi.org/10.1007/s00277-009-0749-z