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Use of rituximab as a salvage therapy for HIV-associated multicentric Castleman disease

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Abstract

Several approved therapies for multicentric Castleman disease (MCD) cannot be uniformly applied due to intolerable side effects. There is also a high percentage of recurrence of this disease despite treatment. Rituximab may be effective in controlling MCD in a subset of patients. This paper includes a brief case report and an extensive review of previously published cases. We observed an aggravation of concomitant cutaneous Kaposi sarcoma, and hypothesize that rituximab could have exacerbated it.

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Correspondence to Angela Casquero.

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Casquero, A., Barroso, A., Fernández Guerrero, M.L. et al. Use of rituximab as a salvage therapy for HIV-associated multicentric Castleman disease. Ann Hematol 85, 185–187 (2006). https://doi.org/10.1007/s00277-005-0038-4

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  • DOI: https://doi.org/10.1007/s00277-005-0038-4

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