Abstract
We describe a 55-year-old woman who presented with pancytopenia with a normocytic and normochromic anemia which was progressive despite conventional treatments such as folic acid, vitamin B6, and oxymetholone. Her physical findings and history of a previous massive postpartum hemorrhage suggested Sheehan’s syndrome, and the pituitary hormonal studies revealed panhypopituitarism. After 4 months of thyroxine and glucocorticoid replacement therapy, her pancytopenia and bone marrow hypoplasia recovered completely. Pancytopenia is a rare manifestation of a hormonal abnormality, but hematologists need to be aware of panhypopituitarism as a differential diagnosis when women showing features of hypopituitarism present with pancytopenia because it can be reversed with adequate hormone replacement.
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This study was supported by a grant from Seoul Municipal Boramae Hospital Clinical Research Fund (2002)
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Kim, DY., Kim, J.H., Park, Y.J. et al. Case of complete recovery of pancytopenia after treatment of hypopituitarism. Ann Hematol 83, 309–312 (2004). https://doi.org/10.1007/s00277-003-0800-4
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DOI: https://doi.org/10.1007/s00277-003-0800-4