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Interleukin-11 administration normalizes the platelet count in a hypersplenic cirrhotic patient

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Abstract.

We report the successful administration of interleukin-11 (IL-11 or oprelvekin), a promoter of megakaryocyte maturation, to a 54-year-old male Jehovah's Witness with hepatic cirrhosis and hypersplenic thrombocytopenia requiring surgery for symptomatic interstitial cystitis. This observation suggests that oprelvekin might be crucial in the acute management of certain types of hypersplenic thrombocytopenias.

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Authors and Affiliations

  1. Section of Hematology/Oncology, Department of Medicine, Medical College of Georgia, 1120 15th Street, BAA 5407, Augusta, GA 30910, USA, , , , ,

    C. Ustun &  P. Dainer

  2. VA Medical Center, Augusta, GA 30912, USA, , , , ,

    G. Faguet

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  1. C. Ustun
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  2. P. Dainer
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  3. G. Faguet
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Ustun, .C., Dainer, .P. & Faguet, .G. Interleukin-11 administration normalizes the platelet count in a hypersplenic cirrhotic patient. Ann Hematol 81, 609–610 (2002). https://doi.org/10.1007/s00277-002-0507-y

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  • DOI: https://doi.org/10.1007/s00277-002-0507-y

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