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Persistent trigeminal artery detected on computed tomography angiography

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Abstract

Purpose

This study aimed to investigate the prevalence of persistent trigeminal arteries (PTAs) using computed tomography (CT) angiography, emphasize its major characteristics, and compare the findings with those reported in the relevant literature.

Methods

Patients who underwent cerebral CT angiography in our radiology clinic for any preliminary diagnosis between December 2013 and December 2020 were included in this retrospective study. The patients were reviewed in terms of their age, sex, and the presence of PTAs. The localization of the PTA, vascular connection, PTA type (according to Saltzman and Salas classification), and vascular pathology at the level of anastomoses were examined in the patients with PTAs.

Results

A total of 1150 patients, (632 [55%] males and 518 [45%] females) were included in this study. A total of seven (0.6%) patients had PTAs. PTAs were located on the right and left sides in three (43%) and four (57%) patients, respectively. A total of three (43%), two (28%), and two (28%) cases were classified as types I, II, and III PTA based on the Saltzman classification, respectively. Moreover, four (57%) and three (43%) cases were lateral and medial types based on the Salas classification, respectively.

Conclusion

In conclusion, understanding the diagnosis and classification of PTAs is crucial for the diagnosis of possible vascular pathologies by neuroradiologists and physicians performing neurovascular interventional procedures or operations. If these vascular pathologies remain undetected, they may cause fatal bleeding or embolism during surgeries and endovascular procedures.

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References

  1. Ali S, Radaideh MM, Shaibani A, Russell EJ, Walker MT (2008) Persistent trigeminal artery terminating in the posterior inferior cerebellar artery: case report. Neurosurgery 62:E746–E748. https://doi.org/10.1227/01.neu.0000317327.17225.f8

    Article  PubMed  Google Scholar 

  2. Arráez-Aybar LA, Fuentes-Redondo T, Millán JM (2016) Persistent trigeminal artery: a cross-sectional study based on over 3 years conventional angiography, CT angiography and MR angiography images. Surg Radiol Anat 38:445–453. https://doi.org/10.1007/s00276-015-1578-5

    Article  PubMed  Google Scholar 

  3. Azab W, Delashaw J, Mohammed M (2012) Persistent primitive trigeminal artery: a review. Turk Neurosurg 22:399–406

    PubMed  Google Scholar 

  4. Bai M, Guo Q, Li S (2013) Persistent trigeminal artery/persistent trigeminal artery variant and coexisting variants of the head and neck vessels diagnosed using 3 T MRA. Clin Radiol 68:e578–e585. https://doi.org/10.1016/j.crad.2013.05.099

    Article  CAS  PubMed  Google Scholar 

  5. Chen Y-C, Li M-H, Chen S-W, Hu D-J, Qiao R-H (2011) Incidental findings of persistent primitive trigeminal artery on 3-dimensional time-of-flight magnetic resonance angiography at 3.0 T: an analysis of 25 cases. J Neuroimaging 21:152–158. https://doi.org/10.1111/j.1552-6569.2010.00472.x

    Article  PubMed  Google Scholar 

  6. Chidambaranathan N, Sayeed ZA, Sunder K, Meera K (2006) Persistent trigeminal artery: a rare cause of trigeminal neuralgia—MR imaging. Neurol India 54:226–227

    CAS  PubMed  Google Scholar 

  7. Conforti R, Parlato RS, De Paulis D et al (2012) Trigeminal neuralgia and persistent trigeminal artery. Neurol Sci 33:1455–1458. https://doi.org/10.1007/s10072-012-0942-z

    Article  PubMed  PubMed Central  Google Scholar 

  8. de Bondt B-J, Stokroos R, Casselman J (2007) Persistent trigeminal artery associated with trigeminal neuralgia: hypothesis of neurovascular compression. Neuroradiology 49:23–26. https://doi.org/10.1007/s00234-006-0150-8

    Article  PubMed  Google Scholar 

  9. Ferreira A, Coelho PS, Cruz VT (2019) Persistent trigeminal artery in a patient with posterior circulation stroke treated with rt-PA: case report. BMC Neurol 19:257. https://doi.org/10.1186/s12883-019-1492-2

    Article  PubMed  PubMed Central  Google Scholar 

  10. Iancu D, Anxionnat R, Bracard S (2010) Brainstem infarction in a patient with internal carotid dissection and persistent trigeminal artery: a case report. BMC Med Imaging 10:14. https://doi.org/10.1186/1471-2342-10-14

    Article  PubMed  PubMed Central  Google Scholar 

  11. Kalmykov MIu, Ternovoĭ SK (2014) The persistent trigeminal artery as evidenced by multislice spiral computed tomographic angiography. Vestn Rentgenol Radiol 5:19–25

    Google Scholar 

  12. Kim MJ, Kim MS (2015) Persistent primitive trigeminal artery: analysis of anatomical characteristics and clinical significances. Surg Radiol Anat 37:69–74. https://doi.org/10.1007/s00276-014-1318-2

    Article  PubMed  Google Scholar 

  13. Kwon JY, Lee EJ, Kim JS (2010) Brainstem infarction secondary to persistent trigeminal artery occlusion: successful treatment with intravenous rt-PA. Eur Neurol 64:311. https://doi.org/10.1159/000321417

    Article  PubMed  Google Scholar 

  14. Meckel S, Spittau B, McAuliffe W (2013) The persistent trigeminal artery: development, imaging anatomy, variants, and associated vascular pathologies. Neuroradiology 55:5–16. https://doi.org/10.1007/s00234-011-0995-3

    Article  PubMed  Google Scholar 

  15. Miller EC, Willey JZ (2016) Bilateral occipital strokes from an atherosclerotic trigeminal artery. Neurology 86:489–490. https://doi.org/10.1212/WNL.0000000000002342

    Article  PubMed  PubMed Central  Google Scholar 

  16. Muttikkal ETJ, Varghese SPJ, Chavan VNK (2007) Persistent trigeminal artery and associated vascular variations. Australas Radiol 51:B31–B33. https://doi.org/10.1111/j.1440-1673.2007.01828.x

    Article  Google Scholar 

  17. O’uchi E, O’uchi T (2010) Persistent primitive trigeminal arteries (PTA) and its variant (PTAV): analysis of 103 cases detected in 16,415 cases of MRA over 3 years. Neuroradiology 52:1111–1119. https://doi.org/10.1007/s00234-010-0669-6

    Article  PubMed  Google Scholar 

  18. Parkinson D, Shields CB (1974) Persistent trigeminal artery: its relationship to the normal branches of the cavernous carotid. J Neurosurg 40:244–248. https://doi.org/10.3171/jns.1974.40.2.0244

    Article  CAS  PubMed  Google Scholar 

  19. Rhee SJ, Kim MS, Lee CH, Lee GJ (2007) Persistent trigeminal artery variant detected by conventional angiography and magnetic resonance angiography-incidence and clinical significance-. J Korean Neurosurg Soc 42:446–449. https://doi.org/10.3340/jkns.2007.42.6.446

    Article  PubMed  PubMed Central  Google Scholar 

  20. Salas E, Ziyal IM, Sekhar LN, Wright DC (1998) Persistent trigeminal artery: an anatomic study. Neurosurgery 43:557–561. https://doi.org/10.1097/00006123-199809000-00082

    Article  CAS  PubMed  Google Scholar 

  21. Saltzman GF (1959) Patent primitive trigeminal artery studied by cerebral angiography. Acta Radiol 51:329–336

    Article  CAS  Google Scholar 

  22. Suzuki S, Chang GY (2010) A case of primitive trigeminal artery infarction. Neurology 75:S66. https://doi.org/10.1212/WNL.0b013e3181fb3604

    Article  PubMed  Google Scholar 

  23. Uchino A, Kato A, Takase Y, Kudo S (2000) Persistent trigeminal artery variants detected by MR angiography. Eur Radiol 10:1801–1804. https://doi.org/10.1007/s003300000443

    Article  CAS  PubMed  Google Scholar 

  24. Uchino A, Saito N, Okada Y et al (2012) Persistent trigeminal artery and its variants on MR angiography. Surg Radiol Anat 34:271–276. https://doi.org/10.1007/s00276-011-0848-0

    Article  PubMed  Google Scholar 

  25. Vasović L, Arsić S, Vlajković S et al (2010) Otic artery: a review of normal and pathological features. Med Sci Monit 16:RA101–RA109

    PubMed  Google Scholar 

  26. Weon YC, Choi SH, Hwang JC, Shin SH, Kwon W-J, Kang BS (2011) Classification of persistent primitive trigeminal artery (PPTA): a reconsideration based on MRA. Acta Radiol 52:1043–1051. https://doi.org/10.1258/ar.2011.110191

    Article  PubMed  Google Scholar 

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Acknowledgements

Our research’s data was presented as an oral presentation at the 42nd National Radiology Congress (TURKRAD-2021, Antalya, 26–31 October 2021).

Funding

The authors did not receive support from any organization for the submitted work.

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Authors and Affiliations

  1. Department of Radiology, Dicle University Medical Faculty, 21070, Sur, Diyarbakır, Turkey

    Muhammed Akif Deniz, Mehmet Turmak & Salih Hattapoğlu

  2. Department of Radiology, Bismil Public Hospital, Diyarbakır, Turkey

    Muhammed Tekinhatun

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  1. Muhammed Akif Deniz
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  2. Mehmet Turmak
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  3. Salih Hattapoğlu
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  4. Muhammed Tekinhatun
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Contributions

MAD: project development, data collection, and manuscript writing. MT: data collection and project development. SH: data collection and manuscript writing. MT: statistical analysis.

Corresponding author

Correspondence to Muhammed Akif Deniz.

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Conflict of interest

The authors have no competing interests to declare that are relevant to the content of this article.

Ethics approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. This study was approved by the local ethics committee (Non-Invasive Clinical Research Ethics Committee, Dicle University Faculty of Medicine; Date: 10.25.2021 Number: 440).

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Informed consent was obtained from all individual participants included in the study.

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Meeting presentation: This study was presented as an oral presentation at the 42nd National Radiology Congress (TURKRAD 2021).

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Deniz, M.A., Turmak, M., Hattapoğlu, S. et al. Persistent trigeminal artery detected on computed tomography angiography. Surg Radiol Anat 44, 715–720 (2022). https://doi.org/10.1007/s00276-022-02960-5

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  • DOI: https://doi.org/10.1007/s00276-022-02960-5

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