Abstract
Purpose
To evaluate the usefulness of a mixture of absolute ethanol and lipiodol in the management of venous malformations.
Methods
Percutaneous sclerotherapy was performed with a mixture of absolute ethanol and lipiodol (9∶1) in 17 patients with venous malformations, once in 12 patients, twice in 5. The therapeutic efficacy was evaluated by pain reduction. Conventional radiographs (n=15) and posttreatment magnetic resonance imaging (n=5) were obtained for the follow-up evaluation.
Results
Sclerotherapy was successful in all but two patients. The therapeutic effect was excellent in two patients, good in seven, fair in five, and poor in one. Radiopacity of lipiodol was beneficial for monitoring the procedure rather than for follow-up evaluations. Areas with low signal-intensity strands were increased on T2-weighted images obtained after the sclerotherapy.
Conclusion
Sclerotherapy with a mixture of ethanol and lipiodol is effective in treating venous malformations.
Similar content being viewed by others
References
Enzinger FM, Weiss SW (1995) Benign tumors and tumorlike lesions of blood vessels. In: Enzinger FM, Weiss SW (eds): Soft Tissue Tumors, 1st ed. Mosby, St. Louis, pp 579–626
Beham A, Fletcher CDM (1991) Intramuscular angioma: A clinicopathological analysis of 74 cases. Histopathology 18:53–59
Meyer JS, Hoffer FA, Barnes PD, Mulliken JB (1991) Biological classification of soft tissue vascular anomalies: MR correlation. AJR 157:559–564
Mulliken JB, Glowacki J (1982) Hemangiomas and vascular malformations in infants and children: A classification based on endothelial characteristics. Plast Reconstr Surg 69:412–420
Mulliken JB, Zetter BR, Folkman J (1982) In vitro characteristics of endothelium from hemangiomas and vascular malformations. Surgery 92:348–353
Jackson IT, Carreno R, Potparic Z, Hussain K (1993) Hemangiomas, vascular malformations, and lymphovenous malformations: Classification and methods of treatment. Plast Reconstr Surg 91:1216–1230
Yakes WF, Haas DK, Parker SH, Gibson MD, Hopper KD, Mulligan JS, Pevsner PH, Johns JC Jr, Carter TE (1989) Symptomatic vascular malformations: Ethanol embolotherapy. Radiology 170:1059–1066
Yakes WF, Pevsner P, Reed M, Donohue HJ, Ghaed N (1986) Serial embolizations of an extremity arteriovenous malformation with alcohol via direct percutaneous puncture. AJR 146:1038–1040
Suh J-S, Hwang G, Hahn S-B (1994) Soft tissue hemangiomas: MR manifestations in 23 patients. Skeletal Radiol 23:621–625
Kransdorf MJ, Jelinek JS, Moser RP Jr, Utz JA, Brower AC, Hudson TM, Berrey BH (1989) Soft-tissue masses: Diagnosis using MR imaging. AJR 153:541–547
Greenspan A, McGahan JP, Vogelsang P, Szabo RM (1992) Imaging strategies in the evaluation of soft tissue hemangiomas of the extremities: Correlation of the findings of plain radiography, angiography, CT, MRI, and ultrasonography in 12 histologically proven cases. Skeletal Radiol 21:11–18
Doppman JL, Pevsner P (1983) Embolization of arteriovenous malformations by direct percutaneous puncture. AJR 140:773–778
Woods JE (1987) Extended use of sodium tetradecyl sulfate in treatment of hemangiomas and other related conditions. Plast Reconstr Surg 79:542–549
Seccia A, Salgarello M (1991) Treatment of angiomas with sclerosing injection of hydroxypolyethoxydodecan. Angiology 42:23–29
Monzani F, Lippi F, Goletti O, Guerra P, Caraccio N, Lippolis PV, Baschieri L, Pinchera A (1994) Percutaneous aspiration and ethanol sclerotherapy for thyroid cysts. J Clin Endocrinol Metab 78:800–802
Hirao Y, Okajima E, Yoshida K, Ozono S, Hayashi Y, Yoshikawa M, Natsume O, Yoshii M, Yasukawa M, Momose H, Yamada T, Hidaka T, Hirohashi S, Matsuo N, Uchida H (1993) Renal ablation with absolute ethanol for nonfunctioning hydronephrosis. Eur Urol 24:203–207
Akhan O, Cekirge S, Ozmen M, Besim A (1992) Percutaneous transcatheter ethanol sclerotherapy of postoperative pelvic lymphoceles. Cardiovasc Intervent Radiol 15:224–227
Ellman BA, Parkhill BJ, Curry TS, Marcus PB, Peters PC (1981) Ablation of renal tumors with absolute ethanol: A new technique. Radiology 141:619–626
Yune HY, O’Connor KW, Klatte EC, Olson EW, Becker GJ, Strickler SA (1985) Ethanol thrombotherapy of esophageal varices: Further experience. AJR 144:1049–1053
Yakes WF, Luethke JM, Parker SH, Stavros AT, Rak KM, Hopper KD, Dreisbach JN, Griffin DJ, Seibert CE, Carter TE, Guilliland JD (1990) Ethanol embolization of vascular malformations. Radiographics 10:787–796
Sasaki M, Tadokoro S, Kimura S, Mori M Kosuda S, Tachibana M (1984) Two cases of renal arteriovenous fistula treated by transcatheter embolization with absolute ethanol. Hinyokika Kiyo 30:295–298
Takebayashi S, Hosaka M, Ishizuka E, Hirokawa M, Matusui K (1988) Arteriovenous malformations of the kidneys: Ablation with alcohol. AJR 150:587–590
Nepper-Rasmussen HJ, Bjerre PK, Jorgensen KE (1993) Endovascular neuroradiologic interventions: Embolization of aneurysms and arteriovenous malformations and sclerotherapy of cavernous hemangiomas. Ugeskr Laeger 155:3471–3476
Zhang JJ (1992) Embolization of drainage veins used in sclerotherapy of hemangiomas. Chung-Hua Wai Ko Tsa Chih (Chinese Journal of Surgery) 30:663–699
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Suh, JS., Shin, KH., Na, JB. et al. Venous malformations: Sclerotherapy with a mixture of ethanol and lipiodol. Cardiovasc Intervent Radiol 20, 268–273 (1997). https://doi.org/10.1007/s002709900150
Issue Date:
DOI: https://doi.org/10.1007/s002709900150