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Transperineal Prostate Core Needle Biopsy: A Comparison of Coaxial Versus Noncoaxial Method in a Randomised Trial

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Abstract

Purpose

To compare the procedural time and complication rate of coaxial technique with those of noncoaxial technique in transperineal prostate biopsy.

Materials and Methods

Transperineal prostate biopsy with coaxial (first group, n = 120) and noncoaxial (second group, n = 120) methods was performed randomly in 240 patients. The procedural time was recorded. The level of pain experienced during the procedure was assessed on a visual analogue scale (VAS), and the rate of complications was evaluated in comparison of the two methods.

Results

The procedural time was significantly shorter in the first group (p < 0.001). In the first group, pain occurred less frequently (p = 0.002), with a significantly lower VAS score being experienced (p < 0.002). No patient had post procedural fever. Haematuria (p = 0.029) and haemorrhage from the site of biopsy (p < 0.001) were seen less frequently in the first group. There was no significant difference in the rate of urethral haemorrhage between the two groups (p = 0.059). Urinary retention occurred less commonly in the first group (p = 0.029). No significant difference was seen in the rate of dysuria between the two groups (p = 0.078).

Conclusions

Transperineal prostate biopsy using a coaxial needle is a faster and less painful method with a lower rate of complications compared with conventional noncoaxial technique.

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Abbreviations

VAS:

Visual analogue scale

PSA:

Prostate-specific antigen

BPH:

Benign prostatic hyperplasia

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Acknowledgments

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Correspondence to Ramin Pourghorban.

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Conflict of Interest

The authors declare that they have no conflict of interests.

Ethical Approval

All procedures performed in this study were in accordance with the ethical standards of the local Institutional Review Board committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed Consent

The written informed consent was obtained from all individual participants included in the study.

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Babaei Jandaghi, A., Habibzadeh, H., Falahatkar, S. et al. Transperineal Prostate Core Needle Biopsy: A Comparison of Coaxial Versus Noncoaxial Method in a Randomised Trial. Cardiovasc Intervent Radiol 39, 1736–1742 (2016). https://doi.org/10.1007/s00270-016-1437-8

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  • DOI: https://doi.org/10.1007/s00270-016-1437-8

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