Abstract
Purpose
Syringes are used for diagnostic fluid aspiration and fine-needle aspiration biopsy in interventional procedures. We determined the benefits, disadvantages, and patient safety implications of syringe and needle size on vacuum generation, hand force requirements, biopsy/fluid yield, and needle control during aspiration procedures.
Materials and Methods
Different sizes (1, 3, 5, 10, and 20 ml) of the conventional syringe and aspirating mechanical safety syringe, the reciprocating procedure device, were studied. Twenty operators performed aspiration procedures with the following outcomes measured: (1) vacuum (torr), (2) time to vacuum (s), (3) hand force to generate vacuum (torr-cm2), (4) operator difficulty during aspiration, (5) biopsy yield (mg), and (6) operator control of the needle tip position (mm).
Results
Vacuum increased tissue biopsy yield at all needle diameters (P < 0.002). Twenty-milliliter syringes achieved a vacuum of −517 torr but required far more strength to aspirate, and resulted in significant loss of needle control (P < 0.002). The 10-ml syringe generated only 15% less vacuum (−435 torr) than the 20-ml device and required much less hand strength. The mechanical syringe generated identical vacuum at all syringe sizes with less hand force (P < 0.002) and provided significantly enhanced needle control (P < 0.002).
Conclusions
To optimize patient safety and control of the needle, and to maximize fluid and tissue yield during aspiration procedures, a two-handed technique and the smallest syringe size adequate for the procedure should be used. If precise needle control or one-handed operation is required, a mechanical safety syringe should be considered.
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Conflict of interest
There was no industry support for this study. All devices were purchased, not donated to this study. Drs. Haseler, R. Sibbitt, Michael, Gasparovic, and Bankhurst have no potential or real conflicts of interest in this study. Dr. Wilmer L. Sibbitt Jr. is funded by Research Grant RO1 HLO77422-01-A3 from the U.S. National Institutes of Health and is a full-time professor at and an employee of the University of New Mexico. The University of New Mexico is the owner of the RPD mechanical syringe technology. Dr. W. Sibbitt also is an expert consultant for Becton–Dickinson, Intelligence Management Solutions, Ferring Pharmaceuticals, Avanca Medical Devices, Avasca, and MediTech Duopross. Dr. Sibbitt holds stock in Apple, Celgene, Avanca, Avasca, Sun Microsystems, Symantec, and Java. In 2009, Abbott Vascular obtained four patents from Dr. Sibbitt, but these do not relate to the present research.
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Haseler, L.J., Sibbitt, R.R., Sibbitt, W.L. et al. Syringe and Needle Size, Syringe Type, Vacuum Generation, and Needle Control in Aspiration Procedures. Cardiovasc Intervent Radiol 34, 590–600 (2011). https://doi.org/10.1007/s00270-010-0011-z
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DOI: https://doi.org/10.1007/s00270-010-0011-z