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Usefulness of Cone-Beam Computed Tomography During Ultraselective Transcatheter Arterial Chemoembolization for Small Hepatocellular Carcinomas that Cannot be Demonstrated on Angiography

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Abstract

This study evaluated the usefulness of cone-beam computed tomography (CBCT) during ultraselective transcatheter arterial chemoembolization (TACE) for hepatocellular carcinomas (HCC) that could not be demonstrated on angiography. Twenty-eight patients with 33 angiographically occult tumors (mean diameter 1.3 ± 0.3 cm) were enrolled in the study. The ability of CBCT during arterial portography (CBCTAP), during hepatic arteriography (CBCTHA), and after iodized oil injection (LipCBCT) to detect HCC lesions was retrospectively analyzed. The technical success of TACE was divided into three grades: complete (the embolized area included the entire tumor with at least a 5-mm wide margin), adequate (the embolized area included the entire tumor but without a 5-mm wide margin in parts), and incomplete (the embolized area did not include the entire tumor) according to computed axial tomographic (CAT) images obtained 1 week after TACE. Local tumor progression was also evaluated. CBCTAP, CBCTHA, and LipCBCT detected HCC lesions in 93.9% (31 of 33), 96.7% (29 of 30), and 100% (29 of 29) of patients, respectively. A single branch was embolized in 28 tumors, and 2 branches were embolized in five tumors. Twenty-seven tumors (81.8%) were classed as complete, and 6 (18.2%) were classed as adequate. None of the tumors were classed as incomplete. Twenty-five tumors (75.8%) had not recurred during 12.0 ± 6.2 months. Eight tumors (24.2%), 5 (18.5%) of 27 complete success and 3 (50%) of 6 adequate success, recurred during 10.1 ± 6.2 months. CBCT during TACE is useful in detecting and treating small HCC lesions that cannot not be demonstrated on angiography.

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Authors and Affiliations

  1. Department of Diagnostic Radiology, Fukuiken Saiseikai Hospital, 7-1 Funabashi, Wadanaka-cho, Fukui, 918-8503, Japan

    Shiro Miyayama, Masashi Yamashiro, Miho Okuda, Yuichi Yoshie, Natsuki Sugimori, Saya Igarashi & Yoshiko Nakashima

  2. Department of Radiology, Kanazawa University Graduate School of Medical Science, 13-1, Takara-machi, Kanazawa, 920-8641, Japan

    Osamu Matsui

Authors
  1. Shiro Miyayama
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  2. Masashi Yamashiro
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  3. Miho Okuda
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  4. Yuichi Yoshie
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  5. Natsuki Sugimori
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  6. Saya Igarashi
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  7. Yoshiko Nakashima
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  8. Osamu Matsui
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Correspondence to Shiro Miyayama.

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Miyayama, S., Yamashiro, M., Okuda, M. et al. Usefulness of Cone-Beam Computed Tomography During Ultraselective Transcatheter Arterial Chemoembolization for Small Hepatocellular Carcinomas that Cannot be Demonstrated on Angiography. Cardiovasc Intervent Radiol 32, 255–264 (2009). https://doi.org/10.1007/s00270-008-9468-4

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  • DOI: https://doi.org/10.1007/s00270-008-9468-4

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