Skip to main content
SpringerLink
Log in

Embolization of an Insulinoma of the Pancreas with Trisacryl Gelatin Microspheres as Definitive Treatment

  • Case Report
  • Published:
CardioVascular and Interventional Radiology Aims and scope Submit manuscript

Abstract

Insulinomas are rare, mostly benign neuroendocrine tumors, originating in 99% of cases from the pancreas, that synthesize and secrete insulin, causing symptomatic hypoglycemia. Today the treatment of choice is surgical removal. We present the case of an 84-year-old woman with a symptomatic insulinoma who refused surgery and was treated with arterial embolization using trisacryl gelatin microspheres as definitive treatment.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

Similar content being viewed by others

References

  1. Moore TJ, Peterson LM, Harrington DP, et al. (1982) Successful arterial embolization of an insulinoma. JAMA 248:1353–1355

    Article  PubMed  CAS  Google Scholar 

  2. Uflacker R (1992) Arterial embolization as definitive treatment for benign insulinoma of the pancreas. JVIR 3:639–644

    PubMed  CAS  Google Scholar 

  3. Gouya H, Vignaux O, Augui J, et al. (2003) CT, endoscopic sonography and a combined protocol for preoperative evaluation of pancreatic insulinomas. AJR 181:987–992

    PubMed  Google Scholar 

  4. Norton JA, Kivlen M, Li M, et al. (2003) Morbidity and mortality of aggressive resection in patients with advanced neuroendocrine tumors. Arch Surg 138:859–866

    Article  PubMed  Google Scholar 

  5. Jaroszewski DE, Schlinkert RT, Thompson GB, et al. (2004) Laparoscopic localization and resection of insulinomas. Arch Surg 139:270–274

    Article  PubMed  Google Scholar 

  6. Lo CY, Lam KY, Kung AW, et al. (1997) Pancreatic insulinomas. A 15-year experience. Arch Surg 132:926–930

    PubMed  CAS  Google Scholar 

  7. Pierce RA, Spitler JA, Hawkins WEG, et al. (2007) Outcomes analysis of laparoscopic resection of pancreatic neoplams. Surg Endosc 21(4):579–586

    Article  PubMed  CAS  Google Scholar 

  8. Mabrut JY, Fernandez-Cruz L, Azagra JS, et al. (2005) Laparoscopic pancreatic resection: results of a multicenter European study of 127 patients. Surgery 137(6):597–605

    Article  PubMed  Google Scholar 

  9. Horton KM, Hruban RH, Yeo C, et al. (2006) Multi-detector row CT of pancreatic islet cell tumors. RadioGraphics 26(2):453–464

    Article  PubMed  Google Scholar 

  10. Laurent A, Beaujeux R, Wassef M, et al. (1996) Trisacryl gelatin microspheres for therapeutic embolization. I: Development and in vitro evaluation. AJNR 17(3):533–540

    PubMed  CAS  Google Scholar 

  11. Pelage JP, Laurent A, Wassef M, et al. (2002) Acute effects of uterine artery embolization in the sheep: comparison between polyvinyl alcohol particles and calibrated microspheres. Radiology 224:436–445

    Article  PubMed  Google Scholar 

  12. Bendszus M, Klein R, Burger R, et al. (2000) Efficacy of trisacryl gelatin microspheres versus polyvinyl alcohol particles in the preoperative embolization of meningeomas. AJNR 21:255–261

    PubMed  CAS  Google Scholar 

  13. Andrew RT, Binkert CA (2003) Relative rates of blood flow reduction during transcatheter arterial embolization with tris-acryl gelatin microspheres or polyvinyl alcohol: quantitative comparison in a swine model. JVIR 14:1311–1316

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Medizinische Klinik, Bethesda-Krankenhaus Duisburg, Heerstrasse 219, Duisburg, 47053, Germany

    Gernot Rott, Martin Biggemann & Martin Pfohl

Authors
  1. Gernot Rott
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Martin Biggemann
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Martin Pfohl
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Gernot Rott.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Rott, G., Biggemann, M. & Pfohl, M. Embolization of an Insulinoma of the Pancreas with Trisacryl Gelatin Microspheres as Definitive Treatment. Cardiovasc Intervent Radiol 31, 659–662 (2008). https://doi.org/10.1007/s00270-007-9185-4

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00270-007-9185-4

Keywords

Search

Navigation