Skip to main content

Advertisement

Log in

The Effect of Single-Anastomosis Sleeve Ileal (SASI) Bypass on Patients with Severe Obesity in Three Consecutive Years

  • Surgery in Low and Middle Income Countries
  • Published:
World Journal of Surgery Aims and scope Submit manuscript

Abstract

Background

Sparse data are available regarding the efficacy and safety of single anastomosis sleeve ileal (SASI) bypass surgery, where most available studies utilized short-term follow-ups. Therefore, this study was conducted to evaluate the safety and outcomes of this procedure in three consecutive years after the surgery.

Materials and methods

This retrospective study was carried out with 116 patients who underwent SASI from October 2016 to September 2021. Anthropometric, clinical, and biochemical data were recorded before, 1, 2, and 3 years after surgery.

Results

The 1, 2, and 3-year percentage of excess weight loss (%EWL) were 87.37%, 90.7%, and 80.6%, respectively. Remission or improvement was recorded for diabetes mellitus in 90.9%, hypertension in 80.0%, hyperlipidemia in 100%, sleep apnea in 100%, and irregular menstruation in 58.06 at 3 years after surgery. No mortality and 5.1% early major postoperative complications were recorded. Eight patients (6.8%) had reversal surgery due to EWL > 100%.

Conclusions

The SASI bypass is an effective bariatric surgery that achieved sequential weight loss and improvement in medical comorbidities three years after the surgery; however, standardization of SASI procedure technique is needed to ameliorate nutritional deficiencies.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Santoro S, Velhote MCP, Malzoni CE et al (2006) Preliminary results from digestive adaptation: a new surgical proposal for treating obesity, based on physiology and evolution. Sao Paulo Med J. https://doi.org/10.1590/s1516-31802006000400004

    Article  PubMed  Google Scholar 

  2. Santoro S, Castro LC, Velhote MCP et al (2012) Sleeve gastrectomy with transit bipartition: a potent intervention for metabolic syndrome and obesity. Ann Surg. https://doi.org/10.1097/SLA.0b013e31825370c0

    Article  PubMed  Google Scholar 

  3. Mahdy T, Alwahedi A, Schou C (2016) Efficacy of single anastomosis sleeve ileal (SASI) bypass for type-2 diabetic morbid obese patients: gastric bipartition, a novel metabolic surgery procedure: a retrospective cohort study. Int J Surg. https://doi.org/10.1016/j.ijsu.2016.08.018

    Article  PubMed  Google Scholar 

  4. Mahdi T, Wahid Alwahidi A, Schou C (2015) Laparoscopic single anastmosis sleeve ileum bypass (SASI bypass): technique and preliminary results. Surg Obes Relat Dis. https://doi.org/10.1016/j.soard.2015.08.266

    Article  Google Scholar 

  5. Lustig RH (2001) The neuroendocrinology of obesity. Endocrinol Metab Clin North Am. https://doi.org/10.1016/S0889-8529(05)70211-5

    Article  PubMed  Google Scholar 

  6. Santoro S, Castro LC, Velhote MCP et al (2012) Sleeve gastrectomy with transit bipartition. Ann Surg. https://doi.org/10.1097/sla.0b013e31825370c0

    Article  PubMed  Google Scholar 

  7. Mui WLM, Lee DWH, Lam KKY (2014) Laparoscopic sleeve gastrectomy with loop bipartition: a novel metabolic operation in treating obese type II diabetes mellitus. Int J Surg Case Rep. https://doi.org/10.1016/j.ijscr.2013.12.002

    Article  PubMed  Google Scholar 

  8. English WJ, DeMaria EJ, Hutter MM et al (2020) American society for metabolic and bariatric surgery 2018 estimate of metabolic and bariatric procedures performed in the United States. Surg Obes Relat Dis. https://doi.org/10.1016/j.soard.2019.12.022

    Article  PubMed  PubMed Central  Google Scholar 

  9. Park CH, Nam SJ, Choi HS et al (2019) Comparative efficacy of bariatric surgery in the treatment of morbid obesity and diabetes mellitus: a systematic review and network meta-analysis. Obes Surg. https://doi.org/10.1007/s11695-019-03831-6

    Article  PubMed  Google Scholar 

  10. Mahdy T, Emile SH, Madyan A et al (2020) Evaluation of the efficacy of single anastomosis sleeve ileal (SASI) bypass for patients with morbid obesity: a multicenter study. Obes Surg. https://doi.org/10.1007/s11695-019-04296-3

    Article  PubMed  Google Scholar 

  11. Kermansaravi M, Kabir A, Pazouki A (2020) 1-year follow-up of single anastomosis sleeve ileal (SASI) bypass in morbid obese patients: efficacy and concerns. Obes Surg. https://doi.org/10.1007/s11695-020-04781-0

    Article  PubMed  PubMed Central  Google Scholar 

  12. Salama TMS, Sabry K, El GY (2017) Single anastomosis sleeve ileal bypass: new step in the evolution of bariatric surgeries. J Investig Surg. https://doi.org/10.1080/08941939.2016.1241841

    Article  Google Scholar 

  13. Emile SH, Madyan A, Mahdy T et al (2020) Single anastomosis sleeve ileal (SASI) bypass versus sleeve gastrectomy: a case-matched multicenter study. Surg Endosc. https://doi.org/10.1007/s00464-020-07430-w

    Article  PubMed  Google Scholar 

  14. Madyan A, Emile SH, Abdel-Razik MA et al (2020) Laparoscopic single anastomosis sleeve ileal (SASI) bypass for patients with morbid obesity: technical description and short-term outcomes. Surg Laparosc Endosc Percutan Tech. https://doi.org/10.1097/SLE.0000000000000763

    Article  PubMed  Google Scholar 

  15. Ezz RS, Abouzeid MM, Helmy MM, Elhusseini MM (2020) Sleeve gastrectomy with loop bipartition as a novel procedure for management of type 2 diabetes in obese patients. QJM An Int J Med. https://doi.org/10.1093/qjmed/hcaa050.010

    Article  Google Scholar 

  16. Mahdy T, Gado W, Alwahidi A et al (2021) Sleeve gastrectomy, one-anastomosis gastric bypass (OAGB), and single anastomosis sleeve ileal (SASI) bypass in treatment of morbid obesity: a retrospective cohort study. Obes Surg. https://doi.org/10.1007/s11695-020-05159-y

    Article  PubMed  Google Scholar 

  17. Mahdy T, Emile SH, Alwahedi A et al (2021) Roux-en-Y gastric bypass with long biliopancreatic limb compared to single anastomosis sleeve ileal (SASI) bypass in treatment of morbid obesity. Obes Surg. https://doi.org/10.1007/s11695-021-05457-z

    Article  PubMed  Google Scholar 

  18. Khalaf M, Hamed H (2021) Single-anastomosis sleeve ileal (SASI) bypass: hopes and concerns after a two-year follow-up. Obes Surg 31(2):667–674. https://doi.org/10.1007/s11695-020-04945-y

    Article  PubMed  Google Scholar 

  19. Emile SH, Mahdy T (2021) Excessive weight loss and hypoalbuminemia after SASI bypass: the need for standardization of the technique. Obes Surg 31(2):865–866

    Article  Google Scholar 

  20. Borgeraas H, Hofsø D, Hertel JK, Hjelmesæth J (2020) Comparison of the effect of Roux-en-Y gastric bypass and sleeve gastrectomy on remission of type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials. Obes Rev 21(6):e13011

    Article  Google Scholar 

  21. McTigue KM, Wellman R, Nauman E et al (2020) Comparing the 5-year diabetes outcomes of sleeve gastrectomy and gastric bypass the national patient-centered clinical research network (PCORNet) bariatric study. JAMA Surg. https://doi.org/10.1001/jamasurg.2020.0087

    Article  PubMed  PubMed Central  Google Scholar 

  22. Holst JJ, Madsbad S, Bojsen-Møller KN et al (2018) Mechanisms in bariatric surgery: gut hormones, diabetes resolution, and weight loss. Surg Obes Relat Dis. https://doi.org/10.1016/j.soard.2018.03.003

    Article  PubMed  PubMed Central  Google Scholar 

  23. Larraufie P, Roberts GP, McGavigan AK et al (2019) Important role of the GLP-1 axis for glucose homeostasis after bariatric surgery. Cell Rep. https://doi.org/10.1016/j.celrep.2019.01.047

    Article  PubMed  PubMed Central  Google Scholar 

  24. Homan J, Boerboom A, Aarts E et al (2018) A longer biliopancreatic limb in Roux-en-Y gastric bypass improves weight loss in the first years after surgery: results of a randomized controlled trial. Obes Surg. https://doi.org/10.1007/s11695-018-3421-7

    Article  PubMed  Google Scholar 

  25. Vennapusa A, Panchangam BRK, Madivada MSS (2017) A feasibility study of novel ‘“laparoscopic sleeve gastrectomy with loop gastroileal bypass”’ for obesity: an Indian experience. Int Surg. https://doi.org/10.9738/INTSURG-D-18-00007.1

    Article  Google Scholar 

  26. Gagner M (2010) Laparoscopic revisional surgery after malabsorptive procedures in bariatric surgery, more specifically after duodenal switch. Surg Laparosc Endosc Percutaneous Tech 20(5):344–347

    Article  Google Scholar 

  27. Surve A, Cottam D, Sanchez-Pernaute A et al (2018) The incidence of complications associated with loop duodeno-ileostomy after single-anastomosis duodenal switch procedures among 1328 patients: a multicenter experience. Surg Obes Relat Dis. https://doi.org/10.1016/j.soard.2018.01.020

    Article  PubMed  Google Scholar 

  28. Gärtner D, Stroh C, Hukauf M et al (2019) Sleeve gastrectomy in the German bariatric surgery registry from 2005 to 2016: perioperative and 5-year results. Surg Obes Relat Dis. https://doi.org/10.1016/j.soard.2018.11.005

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Neda Haghighat.

Ethics declarations

Conflict of interest

None of the authors has any conflict of interest to declare.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Hosseini, S.V., Moeinvaziri, N., Medhati, P. et al. The Effect of Single-Anastomosis Sleeve Ileal (SASI) Bypass on Patients with Severe Obesity in Three Consecutive Years. World J Surg 46, 2744–2750 (2022). https://doi.org/10.1007/s00268-022-06706-7

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00268-022-06706-7

Navigation