Skip to main content
Log in

Comprehensive Complication Index or Clavien–Dindo Classification: Which is Better for Evaluating the Severity of Postoperative Complications Following Pancreatectomy?

  • Original Scientific Report
  • Published:
World Journal of Surgery Aims and scope Submit manuscript

Abstract

Background

Complications are important indicators of immediate postoperative outcomes. The Clavien–Dindo classification (CDC) is a widely used index for the classification of surgical complications. More recently, the comprehensive complication index (CCI) has also been introduced for classifying postoperative complications. The aim of this study was to compare the relationship of CCI and CDC with clinical or economic parameters.

Methods

The study prospectively enrolled patients from April 2015 to October 2016. Two hundred and twenty-two patients underwent pancreatectomy during the enrolled period. Complications were ranked according to CDC and CCI indices. After analyzing the correlation between CCI and CDC, the correlations of length of stay (LOS) and cost with CCI and CDC were compared. Finally, differences between the correlation coefficients of CDC and CCI parameters were calculated.

Results

Complications occurred in 211 patients (95.0%). The correlation between CDC and CCI was r = 0.938. (p < 0.001) Compared to the CDC, CCI showed significantly stronger correlations with LOS and cost of complications (LOS: CCI vs. CDC, r = 0.725 vs. r = 0.630, p < 0.001; cost: CCI vs. CDC, r = 0.774 vs. r = 0.723, p < 0.001).

Conclusion

CCI is a more accurate classification index, compared to CDC, for evaluating the risk of postoperative complications.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Dindo D, Clavien PA (2008) What is a surgical complication? World J Surg 32(6):939–941. https://doi.org/10.1007/s00268-008-9584-y

    Article  PubMed  Google Scholar 

  2. Sokol DK, Wilson J (2008) What is a surgical complication? World J Surg 32(6):942–944. https://doi.org/10.1007/s00268-008-9471-6

    Article  PubMed  Google Scholar 

  3. Collins TC, Daley J, Henderson WH, Khuri SF (1999) Risk factors for prolonged length of stay after major elective surgery. Ann Surg 230(2):251–259

    Article  CAS  Google Scholar 

  4. Schneider EC (2002) Measuring mortality outcomes to improve health care: rational use of ratings and rankings. Med Care 40(1):1–3

    Article  Google Scholar 

  5. Khan NA, Quan H, Bugar JM, Lemaire JB, Brant R, Ghali WA (2006) Association of postoperative complications with hospital costs and length of stay in a tertiary care center. J Gen Intern Med 21(2):177–180

    Article  Google Scholar 

  6. Patel AS, Bergman A, Moore BW, Haglund U (2013) The economic burden of complications occurring in major surgical procedures: a systematic review. Appl Health Econ Health Policy 11(6):577–592

    Article  Google Scholar 

  7. Loppenberg B, von Bodman C, Brock M, Roghmann F, Noldus J, Palisaar RJ (2014) Effect of perioperative complications and functional outcomes on health-related quality of life after radical prostatectomy. Qual Life Res 23(10):2743–2756

    Article  Google Scholar 

  8. Adedeji S, Sokol DK, Palser T, McKneally M (2009) Ethics of surgical complications. World J Surg 33(4):732–737. https://doi.org/10.1007/s00268-008-9907-z

    Article  PubMed  Google Scholar 

  9. Angelos P (2009) Complications, errors, and surgical ethics. World J Surg 33(4):609–611. https://doi.org/10.1007/s00268-008-9914-0

    Article  PubMed  Google Scholar 

  10. Pinto A, Faiz O, Bicknell C, Vincent C (2013) Surgical complications and their implications for surgeons’ well-being. Br J Surg 100(13):1748–1755

    Article  CAS  Google Scholar 

  11. Lermite E, Sommacale D, Piardi T et al (2013) Complications after pancreatic resection: diagnosis, prevention and management. Clin Res Hepatol Gastroenterol 37(3):230–239

    Article  Google Scholar 

  12. Clavien PA, Sanabria JR, Strasberg SM (1992) Proposed classification of complications of surgery with examples of utility in cholecystectomy. Surgery 111(5):518–526

    CAS  PubMed  Google Scholar 

  13. Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240(2):205–213

    Article  Google Scholar 

  14. Strasberg SM, Linehan DC, Hawkins WG (2009) The accordion severity grading system of surgical complications. Ann Surg 250(2):177–186

    Article  Google Scholar 

  15. Slankamenac K, Graf R, Barkun J, Puhan MA, Clavien PA (2013) The comprehensive complication index: a novel continuous scale to measure surgical morbidity. Ann Surg 258(1):1–7

    Article  Google Scholar 

  16. DeOliveira ML, Winter JM, Schafer M et al (2006) Assessment of complications after pancreatic surgery: A novel grading system applied to 633 patients undergoing pancreaticoduodenectomy. Ann Surg 244(6):931–937; discussion 937–939.

  17. Pessaux P, Sauvanet A, Mariette C et al (2011) External pancreatic duct stent decreases pancreatic fistula rate after pancreaticoduodenectomy: prospective multicenter randomized trial. Ann Surg 253(5):879–885

    Article  Google Scholar 

  18. Oberkofler CE, Rickenbacher A, Raptis DA et al (2012) A multicenter randomized clinical trial of primary anastomosis or Hartmann's procedure for perforated left colonic diverticulitis with purulent or fecal peritonitis. Ann Surg 256(5):819–826; discussion 826–817.

  19. Slankamenac K, Nederlof N, Pessaux P et al (2014) The comprehensive complication index: a novel and more sensitive endpoint for assessing outcome and reducing sample size in randomized controlled trials. Ann Surg 260(5):757–762; discussion 762–753.

  20. Slaman AE, Lagarde SM, Gisbertz SS, van Berge Henegouwen MI (2015) A quantified scoring system for postoperative complication severity compared to the Clavien-Dindo classification. Dig Surg 32(5):361–366

    Article  Google Scholar 

  21. Antonacci AC, Lam S, Lavarias V, Homel P, Eavey RD (2008) A morbidity and mortality conference-based classification system for adverse events: surgical outcome analysis: part I. J Surg Res 147(2):172–177

    Article  Google Scholar 

  22. Bassi C, Marchegiani G, Dervenis C et al (2017) The 2016 update of the International Study Group (ISGPS) definition and grading of postoperative pancreatic fistula: 11 Years After. Surgery 161(3):584–591

    Article  Google Scholar 

  23. Fiore JF Jr, Browning L, Bialocerkowski A, Gruen RL, Faragher IG, Denehy L (2012) Hospital discharge criteria following colorectal surgery: a systematic review. Colorectal Dis 14(3):270–281

    Article  Google Scholar 

  24. Evans JD (1996) Straightforward statistics for the behavioral sciences. Brooks/Cole Pub. Co., Pacific Grove

    Google Scholar 

  25. Clavien PA, Barkun J, de Oliveira ML et al (2009) The Clavien-Dindo classification of surgical complications: five-year experience. Ann Surg 250(2):187–196

    Article  Google Scholar 

  26. Grobmyer SR, Pieracci FM, Allen PJ, Brennan MF, Jaques DP (2007) Defining morbidity after pancreaticoduodenectomy: use of a prospective complication grading system. J Am Coll Surg 204(3):356–364

    Article  Google Scholar 

  27. Mbah N, Brown RE, St Hill CR et al (2012) Impact of post-operative complications on quality of life after pancreatectomy. Jop 13(4):387–393

    PubMed  Google Scholar 

  28. Staiger RD, Cimino M, Javed A et al (2018) The Comprehensive Complication Index (CCI(R)) is a novel cost assessment tool for surgical procedures. Ann Surg 268(5):784–791

    Article  Google Scholar 

  29. Bosma E, Pullens MJ, de Vries J, Roukema JA (2016) The impact of complications on quality of life following colorectal surgery: a prospective cohort study to evaluate the Clavien-Dindo classification system. Colorectal Dis 18(6):594–602

    Article  CAS  Google Scholar 

  30. Martin RC 2nd, Brennan MF, Jaques DP (2002) Quality of complication reporting in the surgical literature. Ann Surg 235(6):803–813

    Article  Google Scholar 

  31. Hu Z, Melton GB, Moeller ND et al (2016) Accelerating chart review using automated methods on electronic health record data for postoperative complications. AMIA Annu Symp Proc 2016:1822–1831

    PubMed  Google Scholar 

  32. Murff HJ, FitzHenry F, Matheny ME et al (2011) Automated identification of postoperative complications within an electronic medical record using natural language processing. JAMA 306(8):848–855

    Article  CAS  Google Scholar 

  33. Min L, Liu J, Lu X, Duan H, Qiao Q (2016) An implementation of clinical data repository with openEHR approach: from data modeling to architecture. Stud Health Technol Inform 227:100–105

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Chang Moo Kang.

Ethics declarations

Conflict of interest

The authors declare that they have no conflicts of interest to disclose.

Statement of informed consent

Informed consent was obtained from all individual participants included in the study.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kim, S.H., Hwang, H.K., Lee, W.J. et al. Comprehensive Complication Index or Clavien–Dindo Classification: Which is Better for Evaluating the Severity of Postoperative Complications Following Pancreatectomy?. World J Surg 45, 849–856 (2021). https://doi.org/10.1007/s00268-020-05859-7

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00268-020-05859-7

Navigation