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Wound Disruption Following Colorectal Operations

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Abstract

Objectives

Postoperative wound disruption is associated with high morbidity and mortality. We sought to identify the risk factors and outcomes of wound disruption following colorectal resection.

Methods

The American College of Surgeons National Surgical Quality Improvement Program (NSQIP) database was used to examine the clinical data of patients who underwent colorectal resection from 2005 to 2013. Multivariate regression analysis was performed to identify risk factors of wound disruption.

Results

We sampled a total of 164,297 patients who underwent colorectal resection. Of these, 2073 (1.3 %) had wound disruption. Patients with wound disruption had significantly higher mortality (5.1 vs. 1.9 %, AOR: 1.46, P = 0.01). The highest risk of wound disruption was seen in patients with wound infection (4.8 vs. 0.9 %, AOR: 4.11, P < 0.01). A number of factors are associated with wound disruption such as chronic steroid use (AOR: 1.71, P < 0.01), smoking (AOR: 1.60, P < 0.01), obesity (AOR: 1.57, P < 0.01), operation length more than 3 h (AOR: 1.56, P < 0.01), severe Chronic Obstructive Pulmonary Disease (COPD) (AOR: 1.36, P < 0.01), urgent/emergent admission (AOR: 1.31, P = 0.01), and serum Albumin Level <3 g/dL (AOR: 1.27, P < 0.01). Laparoscopic surgery had significantly lower risk of wound disruption compared to open surgery (AOR: 0.61, P < 0.01).

Conclusion

Wound disruption occurs in 1.3 % of colorectal resections, and it correlates with mortality of patients. Wound infection is the strongest predictor of wound disruption. Chronic steroid use, obesity, severe COPD, prolonged operation, non-elective admission, and serum albumin level are strongly associated with wound disruption. Utilization of the laparoscopic approach may decrease the risk of wound disruption when possible.

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Authors and Affiliations

  1. Department of Surgery, School of Medicine, University of California, Irvine, Irvine, CA, USA

    Zhobin Moghadamyeghaneh, Mark H. Hanna, Joseph C. Carmichael, Steven Mills, Alessio Pigazzi, Ninh T. Nguyen & Michael J. Stamos

  2. John E. Connolly Chair in Surgery, 333 City Blvd. West Suite 1600, Orange, CA, 92868, USA

    Michael J. Stamos

Authors
  1. Zhobin Moghadamyeghaneh
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  2. Mark H. Hanna
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  3. Joseph C. Carmichael
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  4. Steven Mills
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  5. Alessio Pigazzi
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  6. Ninh T. Nguyen
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  7. Michael J. Stamos
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Correspondence to Michael J. Stamos.

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Moghadamyeghaneh, Z., Hanna, M.H., Carmichael, J.C. et al. Wound Disruption Following Colorectal Operations. World J Surg 39, 2999–3007 (2015). https://doi.org/10.1007/s00268-015-3208-0

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  • DOI: https://doi.org/10.1007/s00268-015-3208-0

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