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Long-term Results of the Paraesophagogastric Devascularization with or without Esophageal Transection: Which Is More Suitable for Variceal Bleeding?

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Abstract

Background

It has been reported that the paraesophagogastric devascularization with esophageal transection procedure, also known as the modified Sugiura procedure, was effective in the treatment of variceal bleeding. However, it was not widely accepted by other surgeons because of the high rate of rebleeding, complications, and mortality. To discover the effects of the paraesophagogastric devascularization procedure and the modified Sugiura procedure, we retrospectively analyzed the outcomes of these two procedures.

Materials and methods

During January 1990 and December 2009, 278 patients with variceal bleeding underwent devascularization after failed pharmacotherapy and endotherapy. In these 278 patients, 180 underwent paraesophagogastric devascularization without esophageal transection (group I), and the other 98 patients were subjected to the modified Sugiura procedure (group II).

Results

Postoperative mortality was 7.2 % in group I, and 9.2 % in group II (P = 0.563). The postoperative rebleeding rate in the two groups was 2.2 and 3.1 %, respectively (P = 0.474). After a mean follow-up of 67.9 ± 37.3 months and 67.4 ± 44.6 months, respectively, esophageal transaction-related morbidity (leak, bleeding, and stricture) was 8.2 % (8/98) in group II and 0 % (0/180) in group I (P < 0.001). The overall rebleeding rate was 27 % (41/152) in group I, and 27.2 % (22/81) in group II (P = 0.976). The overall mortality was 28.3 % (43/152) in group I, and 28.4 % (23/81) in group II (P = 0.986).

Conclusions

In the management of variceal bleeding, paraesophagogastric devascularization without esophageal transection is as effective and safe as devascularization with esophageal transaction, but with less esophageal transection-related morbidity.

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Acknowledgments

This work was supported by the 5010 Clinical Research Project of SUN Yat-Sen University (2010009).

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Authors and Affiliations

  1. Department of Hepatobiliary Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, 510120, Guangzhou, China

    He-yun Zhang

  2. Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital of Sun Yat-Sen University, 510120, Guangzhou, China

    He-yun Zhang, Wen-bin Li, Hua Ye, Zhi-yu Xiao, Yao-rong Peng & Jie Wang

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  1. He-yun Zhang
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  2. Wen-bin Li
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  3. Hua Ye
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  4. Zhi-yu Xiao
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  6. Jie Wang
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Corresponding author

Correspondence to Jie Wang.

Additional information

He-yun Zhang and Wen-bin Li have contributed equally to this study.

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Zhang, Hy., Li, Wb., Ye, H. et al. Long-term Results of the Paraesophagogastric Devascularization with or without Esophageal Transection: Which Is More Suitable for Variceal Bleeding?. World J Surg 38, 2105–2112 (2014). https://doi.org/10.1007/s00268-014-2478-2

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