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Comparison of Early and Late Complications after Various Bariatric Procedures: Incidence and Treatment During 15 Years at a Single Institution

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Abstract

Background

Bariatric procedures are effective in the life-long treatment of clinically severe obesity, but they are technically demanding and have known complications. The present study presents mortality and morbidity with different procedures from the prospective 15-year bariatric database of the University Hospital of Patras in Greece.

Methods

From June 1994 through December 2008, 1,162 morbidly obese patients underwent various bariatric procedures at our institution (35 vertical banded gastroplasties, 151 laparoscopic sleeve gastrectomies, 90 open and 137 laparoscopic Roux-en-Y gastric bypasses, 699 biliopancreatic diversions with long limbs, and 50 reoperations). Postoperative metabolic deficiencies and causes of early and late morbidity for various bariatric procedures were compared by using the z-test for the comparison of proportions. Logistic regression analysis was used to model the occurrence of early and late death and complications.

Results

Total mortality was 1.81% (early 0.6%, intermediate 0.26%, late 0.95%). No significant predictors for early death were found, but age (odds ratio (OR), 1.077; 95% confidence interval (CI), 1.024–1.133; P = 0.004) and BMI (OR, 1.156; 95% CI, 1.023–1.306; P = 0.02) were predictors for late death. Early and late morbidity were 8% and 27.71%, respectively. The total leakage incidence was 1.98% and was significantly higher (P < 0.05) after reoperation. Fifteen of the 23 leaks were successfully treated conservatively. Most late complications were incisional hernias (18.85%)—almost all after open procedures. Hypoalbuminemia incidence was significantly higher after biliopancreatic diversion with long limbs (3.58%) and reoperation (8%).

Conclusions

Bariatric procedures, even in specialized centers, may have serious complications because of their technical complexity in a high-risk population. Almost all can be managed successfully.

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References

  1. Deitel M (2003) Overweight and obesity worldwide now estimated to involve 1.7 billion people. Obes Surg 13:329–330

    Article  PubMed  Google Scholar 

  2. Buchwald H, Avidor Y, Braunwald E et al (2004) Bariatric surgery: a systematic review and meta-analysis. JAMA 292:1724–1737

    Article  CAS  PubMed  Google Scholar 

  3. Sjostrom L, Narbro K, Sjostrom CD et al (2007) Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med 357:741–752

    Article  PubMed  Google Scholar 

  4. Christou NV, Sampalis JS, Liberman M et al (2004) Surgery decreases long-term mortality, morbidity, and health care use in morbidly obese patients. Ann Surg 240:416–423

    Article  PubMed  Google Scholar 

  5. Perry CD, Hutter MM, Smith DB et al (2008) Survival and changes in comorbidities after bariatric surgery. Ann Surg 247:21–27

    Article  PubMed  Google Scholar 

  6. Adams TD, Gress RE, Smith SC et al (2007) Long-term mortality after gastric bypass surgery. N Engl J Med 357:753–761

    Article  CAS  PubMed  Google Scholar 

  7. Ballantyne GH, Belsley S, Stephens D et al (2008) Bariatric surgery: low mortality at a high-volume center. Obes Surg 18:660–667

    Article  PubMed  Google Scholar 

  8. Morino M, Toppino M, Forestieri P et al (2007) Mortality after bariatric surgery: analysis of 13, 871 morbidly obese patients from a national registry. Ann Surg 246:1002–1007

    Article  PubMed  Google Scholar 

  9. Buchwald H (2002) A bariatric surgery algorithm. Obes Surg 12:733–746

    Article  PubMed  Google Scholar 

  10. Kalfarentzos F, Dimakopoulos A, Kehagias I et al (1999) Vertical banded gastroplasty versus standard or distal Roux-en-Y gastric bypass based on specific selection criteria in the morbidly obese: preliminary results. Obes Surg 9:433–442

    Article  CAS  PubMed  Google Scholar 

  11. Kalfarentzos F, Skroubis G, Kehagias I et al (2006) A prospective comparison of vertical banded gastroplasty and Roux-en-Y gastric bypass in a non-superobese population. Obes Surg 16:151–158

    Article  PubMed  Google Scholar 

  12. Skroubis G, Anesidis S, Kehagias I et al (2006) Roux-en-Y gastric bypass versus a variant of biliopancreatic diversion in a non-superobese population: prospective comparison of the efficacy and the incidence of metabolic deficiencies. Obes Surg 16:488–495

    Article  PubMed  Google Scholar 

  13. Kalfarentzos F, Kechagias I, Soulikia K et al (2001) Weight loss following vertical banded gastroplasty: intermediate results of a prospective study. Obes Surg 11:265–270

    Article  CAS  PubMed  Google Scholar 

  14. Vagenas K, Panagiotopoulos S, Kehagias I et al (2008) Prospective evaluation of laparoscopic Roux en Y gastric bypass in patients with clinically severe obesity. World J Gastroenterol 14:6024–6029

    Article  PubMed  Google Scholar 

  15. Kalfarentzos F, Papadoulas S, Skroubis G et al (2004) Prospective evaluation of biliopancreatic diversion with Roux-en-Y gastric bypass in the super obese. J Gastrointest Surg 8:479–488

    Article  PubMed  Google Scholar 

  16. Kalfarentzos F, Stavropoulou F, Yarmenitis S et al (2001) Prophylaxis of venous thromboembolism using two different doses of low-molecular-weight heparin (nadroparin) in bariatric surgery: a prospective randomized trial. Obes Surg 11:670–676

    Article  CAS  PubMed  Google Scholar 

  17. Pratt GM, McLees B, Pories WJ (2006) The ASBS Bariatric Surgery Centers of excellence program: a blueprint for quality improvement. Surg Obes Relat Dis 2:497–503

    Article  PubMed  Google Scholar 

  18. Zingmond DS, McGory ML, Ko CY (2005) Hospitalization before and after gastric bypass surgery. JAMA 294:1918–1924

    Article  CAS  PubMed  Google Scholar 

  19. Omalu BI, Ives DG, Buhari AM et al (2007) Death rates and causes of death after bariatric surgery for Pennsylvania residents, 1995–2004. Arch Surg 142:923–928

    Article  PubMed  Google Scholar 

  20. Buchwald H, Estok R, Fahrbach K et al (2007) Trends in mortality in bariatric surgery: a systematic review and meta-analysis. Surgery 142:621–632

    Article  PubMed  Google Scholar 

  21. Flum DR, Salem L, Elrod JA et al (2005) Early mortality among Medicare beneficiaries undergoing bariatric surgical procedures. JAMA 294:1903–1908

    Article  CAS  PubMed  Google Scholar 

  22. Flancbaum L, Belsley S (2007) Factors affecting morbidity and mortality of Roux-en-Y gastric bypass for clinically severe obesity: an analysis of 1, 000 consecutive open cases by a single surgeon. J Gastrointest Surg 11:500–507

    Article  PubMed  Google Scholar 

  23. Sapala JA, Wood MH, Schuhknecht MP et al (2003) Fatal pulmonary embolism after bariatric operations for morbid obesity: a 24-year retrospective analysis. Obes Surg 13:819–825

    Article  PubMed  Google Scholar 

  24. Carmody BJ, Sugerman HJ, Kellum JM et al (2006) Pulmonary embolism complicating bariatric surgery: detailed analysis of a single institution’s 24-year experience. J Am Coll Surg 203:831–837

    Article  PubMed  Google Scholar 

  25. Gracia JA, Martinez M, Elia M et al (2009) Obesity surgery results depending on technique performed: long-term outcome. Obes Surg 19:432–438

    Article  CAS  PubMed  Google Scholar 

  26. Hallowell PT, Stellato TA, Yao DA et al (2009) Should bariatric revisional surgery be avoided secondary to increased morbidity and mortality? Am J Surg 197:391–396

    Article  PubMed  Google Scholar 

  27. Lim CS, Liew V, Talbot ML et al (2009) Revisional bariatric surgery. Obes Surg 19:827–832

    Article  CAS  PubMed  Google Scholar 

  28. Jones KB Jr (2005) Revisional bariatric surgery—potentially safe and effective. Surg Obes Relat Dis 1:599–603

    Article  PubMed  Google Scholar 

  29. Brolin RE, Cody RP (2008) Impact of technological advances on complications of revisional bariatric operations. J Am Coll Surg 206:1137–1144

    Article  PubMed  Google Scholar 

  30. Almahmeed T, Gonzalez R, Nelson LG et al (2007) Morbidity of anastomotic leaks in patients undergoing Roux-en-Y gastric bypass. Arch Surg 142:954–957

    Article  PubMed  Google Scholar 

  31. Durak E, Inabnet WB, Schrope B et al (2008) Incidence and management of enteric leaks after gastric bypass for morbid obesity during a 10-year period. Surg Obes Relat Dis 4:389–393

    Article  PubMed  Google Scholar 

  32. Thodiyil PA, Yenumula P, Rogula T et al (2008) Selective nonoperative management of leaks after gastric bypass: lessons learned from 2675 consecutive patients. Ann Surg 248:782–792

    Article  PubMed  Google Scholar 

  33. Fernandez AZ Jr, DeMaria EJ, Tichansky DS et al (2004) Experience with over 3,000 open and laparoscopic bariatric procedures: multivariate analysis of factors related to leak and resultant mortality. Surg Endosc 18:193–197

    Article  PubMed  Google Scholar 

  34. Lalor PF, Tucker ON, Szomstein S et al (2008) Complications after laparoscopic sleeve gastrectomy. Surg Obes Relat Dis 4:33–38

    Article  PubMed  Google Scholar 

  35. Nocca D, Krawczykowsky D, Bomans B et al (2008) A prospective multicenter study of 163 sleeve gastrectomies: results at 1 and 2 years. Obes Surg 18:560–565

    Article  CAS  PubMed  Google Scholar 

  36. Livingston EH (2005) Complications of bariatric surgery. Surg Clin North Am 85:853–868

    Article  PubMed  Google Scholar 

  37. Gonzalez R, Sarr MG, Smith CD et al (2007) Diagnosis and contemporary management of anastomotic leaks after gastric bypass for obesity. J Am Coll Surg 204:47–55

    Article  PubMed  Google Scholar 

  38. Eubanks S, Edwards CA, Fearing NM et al (2008) Use of endoscopic stents to treat anastomotic complications after bariatric surgery. J Am Coll Surg 206:935–938

    Article  PubMed  Google Scholar 

  39. Salinas A, Baptista A, Santiago E et al (2006) Self-expandable metal stents to treat gastric leaks. Surg Obes Relat Dis 2:570–572

    Article  PubMed  Google Scholar 

  40. Ballesta C, Berindoague R, Cabrera M et al (2008) Management of anastomotic leaks after laparoscopic Roux-en-Y gastric bypass. Obes Surg 18:623–630

    Article  PubMed  Google Scholar 

  41. Davies DJ, Baxter JM, Baxter JN (2007) Nutritional deficiencies after bariatric surgery. Obes Surg 17:1150–1158

    Article  CAS  PubMed  Google Scholar 

  42. Skroubis G, Sakellaropoulos G, Pouggouras K et al (2002) Comparison of nutritional deficiencies after Roux-en-Y gastric bypass and after biliopancreatic diversion with Roux-en-Y gastric bypass. Obes Surg 12:551–558

    Article  PubMed  Google Scholar 

  43. Mason EE, Renquist KE (2002) Gallbladder management in obesity surgery. Obes Surg 12:222–229

    Article  PubMed  Google Scholar 

  44. Hollenbeak CS, Rogers AM, Barrus B et al (2008) Surgical volume impacts bariatric surgery mortality: a case for centers of excellence. Surgery 144:736–743

    Article  PubMed  Google Scholar 

Download references

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Correspondence to Fotis Kalfarentzos.

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Skroubis, G., Karamanakos, S., Sakellaropoulos, G. et al. Comparison of Early and Late Complications after Various Bariatric Procedures: Incidence and Treatment During 15 Years at a Single Institution. World J Surg 35, 93–101 (2011). https://doi.org/10.1007/s00268-010-0816-6

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  • DOI: https://doi.org/10.1007/s00268-010-0816-6

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