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Has the Accuracy of Preoperative Diagnosis Improved in Cases of Early-stage Gastric Cancer?

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Abstract

Background

Adequate preoperative evaluation for gastric cancer staging is essential to develop an individualized treatment strategy involving surgery with reduced lymphadenectomy and laparoscopic gastrectomy.

Methods

A total of 509 gastric cancer patients with clinical Stage IA or IB disease were divided into two groups: 304 patients were admitted in 2000 or earlier (Group A), and 205 patients were admitted in 2001, when multidetector computed tomography (MD-CT) was available, or later (Group B). We evaluated the accuracy of the preoperative diagnoses of tumor depth, lymph node involvement, and tumor stage.

Results

With respect to tumor depth, 94.5 and 52.8% of patients were staged correctly in cT1 and cT2 patients, respectively. Among both cT1 and cT2 patients, the underestimated rates were lower in Group B than in Group A. For nodal metastasis, 83.2 and 30.0% of patients were staged correctly in cN0 and cN1 patients, respectively. Among the cN0 patients, 82.1 and 84.7% of Group A and Group B patients, respectively, were staged correctly. Among the cN1 patients, none of the patients in Group B was underestimated, while 9.7% of Group A patients were underestimated. There was a significant increase in the percentage of correctly staged patients and a decrease in the percentage of underestimated patients in Group B in comparison to Group A in both cStage IA and cStage IB patients.

Conclusions

Remarkable advances have been observed in the accuracy of preoperative staging in the early stage of gastric cancer. However, it is necessary to continue to develop accurate preoperative and intraoperative diagnostic systems.

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Acknowledgments

The authors thank Shuichi Hiraki, Naoko Sakamoto, Yoshihisa Yaguchi, Takuya Horio, Isao Kumano, Risa Takahata, Yusuke Matsumoto, Kazumichi Yoshida, and Satoshi Aiko, Department of Surgery, National Defense Medical College, for collecting the data and critical revision of the manuscript.

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Authors and Affiliations

  1. Department of Surgery, National Defense Medical College, 3-2 Namiki, Tokorozawa, 359-8513, Japan

    Hironori Tsujimoto, Hidekazu Sugasawa, Satoshi Ono, Takashi Ichikura, Junji Yamamoto & Kazuo Hase

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  1. Hironori Tsujimoto
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  2. Hidekazu Sugasawa
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  3. Satoshi Ono
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  4. Takashi Ichikura
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  5. Junji Yamamoto
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  6. Kazuo Hase
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Correspondence to Hironori Tsujimoto.

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Tsujimoto, H., Sugasawa, H., Ono, S. et al. Has the Accuracy of Preoperative Diagnosis Improved in Cases of Early-stage Gastric Cancer?. World J Surg 34, 1840–1846 (2010). https://doi.org/10.1007/s00268-010-0587-0

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  • DOI: https://doi.org/10.1007/s00268-010-0587-0

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