Abstract
It has been suggested that gastric cancer has a worse prognosis in young patients, but the data are controversial. The aim of this study was to compare the 5-year survivals after gastrectomy for gastric cancer in two groups of patients (those ≤45 years of age and those (>45 years) and to determine some of the prognostic factors. The 5-year survival was significantly better for patients ≤45 years of age. Survival was also better for young patients with a curative resection and also for those with lymph node metastases. However, survival was not significantly different for the two groups when the resection was not curative and when the lymph nodes were not involved. Survival was no different for the two groups when compared at each stage, although a multivariate analysis showed that age >45 years, moderate or poor degree of differentiation of the tumor, advanced tumors, the presence of lymph node involvement, and a noncurative resection were independent negative prognostic factors. Long-term survival after gastrectomy for gastric cancer depends on the stage of the disease; the age of the patient is not a decisive factor.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Hohenberger P, Gretschel S. Gastric cancer. Lancet 2003;362:305–315
Kokkola A, Sipponen P. Gastric carcinoma in young adults. Hepatogastroenterology 2001;48:1552–1555
American Cancer Society. American Joint Committee on Cancer. AJCC Cancer Staging Manual,. 5th edition, Philadelphia, Lippincott-Raven, 1997
Llanos O, Guzmán S, Pimentel F, et al. Results of surgical treatment of gastric cancer. Dig Surg 1999;16:385–388
Fuchs CS, Mayer RJ. Gastric carcinoma. N Engl J Med 1995;333:32–41
Theuer CP, de Virgilio C, Keese G, et al. Gastric adenocarcinoma in patients 40 years of age or younger. Am J Surg 1996;172:473–476
Medina-Franco H, Heslin Mj, Cortes-Gonzalez R. Clinicopathological characteristics of gastric carcinoma in young and elderly patients: a comparative study. Ann Surg Oncol 2000;7:515–519
Kitamura K, Yamaguchi T, Yamamoto K, et al. Clinicopathological analysis of gastric cancer in young adults. Hepatogastroenterology 1996;43:1273–1280
Matley PJ, Dent DM, Madden MV, et al. Gastric carcinoma in young adults. Ann Surg 1988;208:593–596
Tso PL, Bringaze WL, Dauterive AH. Gastric carcinoma in the young. Cancer 1987;59:1362–1365
Wanebo HJ, Kennedy BJ, Chmiel J, et al. Cancer of the stomach: a patient care study by the American College of Surgeons. Ann Surg 1993;218:583–592
Eguchi T, Takahashi Y, Yamagata M, et al. Gastric cancer in young patients. J Am Coll Surg 1999;188:22–26
Duarte I, Ohmke J, Ciani S, et al. Patterns of carcinoma in gastrectomy specimens from Chilean adults; a multivariate analysis in a high-risk area. Gastr Latinoam 2001;12:12–18
Quijano F, Moreno E, Alvarez JJ, et al. Gastric carcinoma in patients under 35 years. Rev Gastroenterol Mex 1999;64:75–77
Koea JB, Karpeh MS, Brennan MF. Gastric cancer in young patients: demographic, clinicopathological and prognostic factors in 92 patients. Ann Surg Oncol 2000;7:346–351
Lai IR, Lee WJ, Chen CN, et al. Gastric cancer in the young. Hepatogastroenterology 1997;44:1641–1645
Maehara Y, Emi Y, Tomisaki S, et al. Age-related characteristics of gastric carcinoma in young and elderly patients. Cancer 1996;77:1774–1780
Ramos-De la Medina A, Salgado-Nesme N, Torres-Villalobos G, et al. Clinicopathologic characteristics of gastric cancer in a young patient population. J Gastrointest Surg 2004;8:240–244
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Llanos, O., Butte, J.M., Crovari, F. et al. Survival of Young Patients after Gastrectomy for Gastric Cancer. World J. Surg. 30, 17–20 (2006). https://doi.org/10.1007/s00268-005-7935-5
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00268-005-7935-5