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Reoperative Surgery for Chronic Pancreatitis: Is It Safe?

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Abstract

Introduction

Eleven percent to fifty-six percent of patients do not achieve adequate pain relief with initial operative treatment for chronic pancreatitis, and reoperations for recurrent or persistent pain are common. This study evaluates the influence of prior pancreatic procedures on operative morbidity for chronic pancreatitis.

Methods

The records of 336 consecutive patients who underwent pancreaticoduodenectomy (PD, n = 78), lateral pancreaticojejunostomy (LPJ, n = 152), distal pancreatectomy (DP, n = 83), transduodenal sphincteroplasty (SP, n = 20), and total pancreatectomy (TP, n = 3) for chronic pancreatitis were retrospectively reviewed and analyzed.

Results

Seventy-four patients underwent reoperation after failed prior pancreatic surgery. Patients with de novo pancreatic operations had a similar complication rate as those with reoperation (PD: 48% versus 65%, P > 0.05; LPJ: 23% versus 23%, P > 0.05; DP: 26% versus 28%, P > 0.05; SP: 21% versus 100%, P > 0.05). Major complications such as pancreatic leak or abdominal abscess were similar in the two groups. Minor complications such as delayed gastric emptying or wound infections were more common in the reoperation group. There was no difference in postoperative hospital length of stay.

Conclusions

Patients who undergo reoperative surgery for chronic pancreatitis have an increased risk for minor perioperative complications. The overall complication rate and the incidence of major complications are similar compared to de novo procedure. Reoperative surgery therefore appears feasible and safe in experienced hands.

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References

  1. Sakorafas GH, Farnell MB, Nagorney DM, et al. Pancreatoduodenectomy for chronic pancreatitis: long-term results in 105 patients. Arch Surg 2000;135:517–523

    Article  PubMed  CAS  Google Scholar 

  2. Rumstadt B, Forssmann K, Singer MV, et al. The Whipple partial duodenopancreatectomy for the treatment of chronic pancreatitis. Hepatogastroenterology 1997;44:1554–1559

    PubMed  CAS  Google Scholar 

  3. Russell RCG, Theis BA. Pancreatoduodenectomy in the treatment of chronic pancreatitis. World J Surg 2003;27:1203–1210

    Article  PubMed  Google Scholar 

  4. Beger HG, Schlosser W, Friess HM, et al. Duodenum-preserving head resection in chronic pancreatitis changes the natural course of the disease: a single-center 26-year experience. Ann Surg 1999;230:512–519

    Article  PubMed  CAS  Google Scholar 

  5. Adams DB, Ford MC, Anderson MC. Outcome after lateral pancreaticojejunostomy for chronic pancreatitis. Ann. Surg. 1994;219:481–489

    PubMed  CAS  Google Scholar 

  6. Ho HS, Frey CF. The Frey procedure: local resection of pancreatic head combined with lateral pancreaticojejunostomy. Arch Surg 2001;136:1353–1358

    Article  PubMed  CAS  Google Scholar 

  7. Hutchins RR, Hart RS, Pacifico M, et al. Long-term results of distal pancreatectomy for chronic pancreatitis in 90 patients. Ann. Surg. 2002;236:612–618

    Article  PubMed  Google Scholar 

  8. Sakorafas GH, Sarr MG, Rowland CM, et al. Postobstructive chronic pancreatitis: results with distal resection. Arch Surg 2001;136:643–648

    Article  PubMed  CAS  Google Scholar 

  9. Bagley FH, Braasch JW, Taylor RH, et al. Sphincterotomy or sphincteroplasty in the treatment of pathologically mild chronic pancreatitis. Am J Surg 1981;141:418–422

    Article  PubMed  CAS  Google Scholar 

  10. Tzovaras G, Rowlands BJ. Transduodenal sphincteroplasty and transampullary septectomy for sphincter of Oddi dysfunction. Ann R Coll Surg Engl 2002;84:14–19

    PubMed  Google Scholar 

  11. Prinz RA, Aranha GV, Greenlee HB. Redrainage of the pancreatic duct in chronic pancreatitis. Am J Surg 1986;151:150–156

    Article  PubMed  CAS  Google Scholar 

  12. Markowitz JS, Rattner DW, Warshaw AL. Failure of symptomatic relief after pancreaticojejunal decompression for chronic pancreatitis. Arch Surg 1994;129:374–380

    PubMed  CAS  Google Scholar 

  13. Ammann RW, Heitz PU, Kloppel G. Course of alcoholic chronic pancreatitis: a prospective clinicomorphologic long-term study. Gastroenterology 1996;111:224–231

    Article  PubMed  CAS  Google Scholar 

  14. Imrie CW. Management of recurrent pain following previous surgery for chronic pancreatitis. World J Surg 1990;14:88–93

    Article  PubMed  CAS  Google Scholar 

  15. Paye F, Frileux P, Lehman P, et al. Reoperation for severe pancreatitis: a 10-year experience in a tertiary care center. Arch Surg 1999;134:316–320

    Article  PubMed  CAS  Google Scholar 

  16. Fry DE, Osler T. Abdominal wall considerations and complications in reoperative surgery. Surg Clin North Am 1991;71:1–12

    PubMed  CAS  Google Scholar 

  17. Fevang BT, Fevang J, Lie SA, et al. Long-term prognosis after operation for adhesive small bowel obstruction. Ann Surg 2004;240:193–201

    Article  PubMed  Google Scholar 

  18. Harris EA, Kelly AW, Pockaj BA, et al. Reoperation on the abdomen encased in adhesions. Am J Surg 2002;184:499–504

    Article  PubMed  Google Scholar 

  19. Fabri PJ, Rosemurgy A. Reoperation for small intestinal obstruction. Surg Clin North Am 1991;71:131–146

    PubMed  CAS  Google Scholar 

  20. McFadden DW, Zinner MJ. Reoperation for recurrent peptic ulcer disease. Surg Clin North Am 1991;71:77–92

    PubMed  CAS  Google Scholar 

  21. Doberneck RC. Revision and closure of the colostomy. Surg Clin North Am 1991;71:193–201

    PubMed  CAS  Google Scholar 

  22. Tyler DS, Evans DB. Reoperative pancreaticoduodenectomy. Ann Surg. 1994;219:211–221

    PubMed  CAS  Google Scholar 

  23. Sohn TA, Lillemoe KD, Cameron JL, et al. Reexploration for periampullary carcinoma. Ann Surg 1999;229:393–400

    Article  PubMed  CAS  Google Scholar 

  24. VanBerge Henegouwen MI, VanGulik TM, DeWit LT, et al. Delayed gastric emptying after standard pancreaticoduodenectomy versus pylorus-preserving pancreaticoduodenectomy: an analysis of 200 consecutive patients. J Am Coll Surg 1997;185:373–379

    Article  CAS  Google Scholar 

  25. Riediger H, Makowiec F, Schareck WD, et al. Delayed gastric emptying after pylorus-preserving pancreatoduodenectomy is strongly related to other postoperative complications. J Gastrointest Surg 2003;7:758–765

    Article  PubMed  Google Scholar 

  26. Kimura F, Suwa T, Sugiura T, et al. Sepsis delays gastric emptying following pylorus-preserving pancreaticoduodenectomy. Hepatogastroenterology 2002;49:585–588

    PubMed  Google Scholar 

  27. Fabre JM, Burgel JS, Navarro F, et al. Delayed gastric emptying after pancreaticoduodenectomy and pancreaticogastrostomy. Eur J Surg 1999;165:560–565

    Article  PubMed  CAS  Google Scholar 

  28. Johnson CP, Sarna SK, Cowles VE, et al. Effects of transection and reanastomosis on postprandial jejunal transit and contractile activity. Surgery 1995;117:531–537

    Article  PubMed  CAS  Google Scholar 

  29. Tanaka M, Dalton RR, Smith CD, et al. The role of myoneural and luminal continuity in the coordination of canine gastroduodenal patterns of motility. J Surg Res 1992;53:588–595

    Article  PubMed  CAS  Google Scholar 

  30. Hart SC, Nguyen-Tu BL, Hould FS, et al. Restoration of myoelectrical propagation across a jejunal transection using microsurgical anastomosis. J Gastrointest Surg 1999;3:524–532

    Article  PubMed  CAS  Google Scholar 

  31. Wilson MA. Skin and soft-tissue infections: impact of resistant gram-positive bacteria. Am J Surg 2003;186:35S–41S

    Article  PubMed  Google Scholar 

  32. Brinton MH, Pellegrini CA, Stein SF, et al. Surgical treatment of chronic pancreatitis. Am J Surg 1984;148:754–759

    Article  PubMed  CAS  Google Scholar 

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Correspondence to Thomas Schnelldorfer MD.

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Schnelldorfer, T., Lewin, D.N. & Adams, D.B. Reoperative Surgery for Chronic Pancreatitis: Is It Safe?. World J. Surg. 30, 1321–1328 (2006). https://doi.org/10.1007/s00268-005-7908-8

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  • DOI: https://doi.org/10.1007/s00268-005-7908-8

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