Skip to main content
SpringerLink
Log in

Cancer of the Parotid Gland: Role of 7th Nerve Preservation

  • World Progress in Surgery
  • Published:
World Journal of Surgery Aims and scope Submit manuscript

Abstract

Most neoplasms arising in the parotid gland are benign. Patients with cancer of the parotid gland usually present with normal facial nerve function. In these patients, findings at the time of surgery will guide the management of the facial nerve, with most surgeons preserving the nerve unless it is adherent to, or imbedded in, a malignant tumor. In cases where the margins of resection are close to the facial nerve, adjuvant radiotherapy administered postoperatively has significantly improved local control of disease. The minority of patients with parotid cancer who present with facial nerve palsy has a poor prognosis despite extensive surgical resection including the facial nerve.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1.

Similar content being viewed by others

References

  1. AD Katz P Catalano (1987) ArticleTitleThe clinical significance of the various anastamotic branches of the facial nerve: report of 100 patients Arch. Otolaryngol. 113 959–962 Occurrence Handle1:STN:280:BiiB2s7itVI%3D

    CAS  Google Scholar 

  2. JG Batsakis (1986) ArticleTitleHeterotopic and accessory salivary tissue Ann. Otol. Rhinol. Laryngol. 95 434–436 Occurrence Handle1:STN:280:BimB1MvgvF0%3D Occurrence Handle3740723

    CAS  PubMed  Google Scholar 

  3. JJ Conley (1975) Salivary Glands and the Facial Nerve Grune and Stratton New York

    Google Scholar 

  4. J Yoel (1975) Pathology and Surgery of the Salivary Glands Charles C. Thomas Springfield, IL

    Google Scholar 

  5. RH Spiro AW Huvos EW Strong (1975) ArticleTitleCancer of the parotid gland: a clinicopathologic study of 288 primary cases Am. J. Surg. 130 452–459 Occurrence Handle1:STN:280:CSmD3sjptVc%3D Occurrence Handle170839

    CAS  PubMed  Google Scholar 

  6. RH Spiro (1986) ArticleTitleSalivary neoplasms: overview of a 35 year experience with 2,807 patients Head Neck Surg. 8 77–84

    Google Scholar 

  7. CM Eneroth (1971) ArticleTitleSalivary gland tumors in the parotid gland, submandibular gland, and the palate region Cancer 27 1415–1418 Occurrence Handle1:STN:280:CS6B38rjtVI%3D Occurrence Handle4325986

    CAS  PubMed  Google Scholar 

  8. JW Eveson RA Cawson (1985) ArticleTitleSalivary gland tumours: a review of 2410 cases with particular reference to histological types, site, age and sex distribution J. Pathol. 146 51–58 Occurrence Handle1:STN:280:BiqB3snntFI%3D Occurrence Handle4009321

    CAS  PubMed  Google Scholar 

  9. JE Woods GC Cheng OH Beahrs (1975) ArticleTitleExperience with 1,360 primary parotid tumors Am. J. Surg. 130 460–462 Occurrence Handle1:STN:280:CSmD3sjptVA%3D Occurrence Handle1166937

    CAS  PubMed  Google Scholar 

  10. D Pedersen J Overgaard H Sogaard et al. (1992) ArticleTitleMalignant parotid tumors in 110 consecutive patients: treatment results and prognosis Laryngoscope 102 1064–1069

    Google Scholar 

  11. A Renehan EN Gleave BD Hancock et al. (1986) ArticleTitleLong-term follow-up of over 1000 patients with salivary gland tumours treated in a single center Br. J. Surg. 83 1750–1754

    Google Scholar 

  12. S Rafla (1977) ArticleTitleMalignant parotid tumors: natural history and treatment Cancer 40 136–144 Occurrence Handle1:STN:280:CSiB38zjvFw%3D Occurrence Handle195701

    CAS  PubMed  Google Scholar 

  13. A Borthune . Kjellevold O Kaalhus et al. (1986) ArticleTitleSalivary gland malignant neoplasms: treatment and prognosis Int. J. Radiat. Oncol. Biol. Phys. 12 747–754 Occurrence Handle3710859

    PubMed  Google Scholar 

  14. RA Frankenthaler MA Luna SS Lee et al. (1991) ArticleTitlePrognostic variables in parotid cancer Arch. Otolaryngol. Head Neck Surg. 117 1251–1256 Occurrence Handle1:STN:280:By2D1c3mtlE%3D Occurrence Handle1747227

    CAS  PubMed  Google Scholar 

  15. CM Eneroth (1972) ArticleTitleFacial nerve paralysis: a criterion of malignancy in parotid tumors Arch. Otolaryngol. 95 300–304 Occurrence Handle1:STN:280:CS2C2Mbktl0%3D Occurrence Handle4336149

    CAS  PubMed  Google Scholar 

  16. JJ Conley RC Hamaker (1975) ArticleTitlePrognosis of malignant tumors of the parotid gland with facial paralysis Arch. Otolaryngol. 101 39–41 Occurrence Handle1:STN:280:CSqC38jht1E%3D Occurrence Handle164169

    CAS  PubMed  Google Scholar 

  17. G Tu Y Hu P Jiang et al. (1982) ArticleTitleThe superiority of combined therapy in parotid cancer Arch. Otolaryngol. 108 710–713 Occurrence Handle1:STN:280:BiyD2cjotl0%3D Occurrence Handle7138365

    CAS  PubMed  Google Scholar 

  18. RD Lindberg M Ackerman (1976) ArticleTitleAspiration cytology of salivary gland tumors: diagnostic experience from six years of routine laboratory work Laryngoscope 86 584–589

    Google Scholar 

  19. P O’Dwyer WB Farrar AG James et al. (1986) ArticleTitleNeedle aspiration biopsy of major salivary gland tumors: its value Cancer 57 554–557 Occurrence Handle1:STN:280:BimC3crmsVw%3D Occurrence Handle3942989

    CAS  PubMed  Google Scholar 

  20. LJ Layfield P Tan BJ Glasgow (1987) ArticleTitleFine needle aspiration of salivary gland lesions: comparison with frozen sections and histologic findings Arch. Pathol. Lab. Med. 111 346–353 Occurrence Handle1:STN:280:BiiC2MrosVw%3D Occurrence Handle3030228

    CAS  PubMed  Google Scholar 

  21. T Atula R Greenman P Laippala et al. (1996) ArticleTitleFine-needle aspiration biopsy in the diagnosis of parotid gland lesions: evaluation of 438 biopsies Diagn. Cytopathol. 15 185–190 Occurrence Handle10.1002/(SICI)1097-0339(199609)15:3<185::AID-DC2>3.0.CO;2-G Occurrence Handle1:STN:280:ByiC3MznsFw%3D Occurrence Handle8955598

    Article  CAS  PubMed  Google Scholar 

  22. BM Al-Khafaji BR Nestok RL Katz (1998) ArticleTitleFine-needle aspiration of 154 parotid masses with histologic correlation: ten-year experience at the University of Texas M.D Anderson Cancer Center. Cancer 84 153–159 Occurrence Handle10.1002/(SICI)1097-0142(19980625)84:3<153::AID-CNCR6>3.3.CO;2-7 Occurrence Handle1:STN:280:DyaK1czktFyluw%3D%3D

    Article  CAS  Google Scholar 

  23. JL Weissman (1995) ArticleTitleImaging of the salivary glands Semin. Ultrasound. CT MR 16 546–568 Occurrence Handle1:STN:280:BymA28zmtVE%3D Occurrence Handle8747417

    CAS  PubMed  Google Scholar 

  24. T Dailiana D Chakeres P Schmalbrock et al. (1997) ArticleTitleHigh resolution MR of the intraparotid facial nerve and parotid duct AJNR. Am. J. Neuroradiol. 18 165–172 Occurrence Handle1:STN:280:ByiC28znt10%3D Occurrence Handle9010536

    CAS  PubMed  Google Scholar 

  25. MF Nigro RH Spiro (1977) ArticleTitleDeep lobe parotid tumors Am. J. Surg. 134 523–527 Occurrence Handle911039

    PubMed  Google Scholar 

  26. AD Hillel WE Fee (1983) ArticleTitleEvaluation of frozen section in parotid gland surgery Arch. Otolaryngol. 109 230–232 Occurrence Handle1:STN:280:BiyC2M3ktlQ%3D Occurrence Handle6830515

    CAS  PubMed  Google Scholar 

  27. RF Wheelis CT Yarrington SuffixJr (1984) ArticleTitleTumors of the salivary glands: comparison of frozen section diagnosis with final pathologic diagnosis Arch. Otolaryngol. 110 76–77 Occurrence Handle1:STN:280:BiuC38jlt1M%3D Occurrence Handle6696688

    CAS  PubMed  Google Scholar 

  28. MS Granick ER Erickson DC Hanna (1985) ArticleTitleAccuracy of frozen section diagnosis in salivary gland lesions Head Neck Surg. 7 465–467 Occurrence Handle1:STN:280:BimD3cjlsV0%3D Occurrence Handle4044266

    CAS  PubMed  Google Scholar 

  29. DR Gnepp WR Rader SF Cramer et al. (1987) ArticleTitleAccuracy of frozen section diagnosis in salivary gland lesions Otolaryngol. Head Neck Surg. 96 325–330 Occurrence Handle1:STN:280:BiiB3s%2FktVY%3D Occurrence Handle3108819

    CAS  PubMed  Google Scholar 

  30. PG Reddy RL Arden RH Mathog (1999) ArticleTitleFacial nerve rehabilitation after radical parotidectomy Laryngoscope 109 894–899

    Google Scholar 

  31. JD Kerrebijn JL Freeman (1998) ArticleTitleFacial nerve reconstruction: outcomes and failures J. Otolaryngol. 27 183–186

    Google Scholar 

  32. O Gallo A Franchi GV Bottai et al. (1997) ArticleTitleRisk factors for distant metastases from carcinoma of the parotid gland Cancer 80 844–851 Occurrence Handle10.1002/(SICI)1097-0142(19970901)80:5<844::AID-CNCR3>3.3.CO;2-L Occurrence Handle1:STN:280:ByiH2M%2FnsVU%3D Occurrence Handle9307182

    Article  CAS  PubMed  Google Scholar 

  33. C Calearo A Pastore OF Storchi et al. (1998) ArticleTitleParotid gland carcinoma: analysis of prognostic factors Ann. Otol. Rhinol. Laryngol. 107 969–973 Occurrence Handle1:STN:280:DyaK1M%2FjvFCmtg%3D%3D Occurrence Handle9823848

    CAS  PubMed  Google Scholar 

  34. RH Spiro J Armstrong LB Harrison et al. (1989) ArticleTitleCarcinoma of the major salivary glands: recent trends Arch. Otolaryngol. Head Neck Surg. 115 316–321 Occurrence Handle1:STN:280:BiaC3svksFY%3D Occurrence Handle2537093

    CAS  PubMed  Google Scholar 

  35. AG Renehan EN Gleave NJ Slevin et al. (1999) ArticleTitleClinico-pathological and treatment-related factors influencing survival in parotid cancer Br. J. Surg. 80 1296–1300 Occurrence Handle10.1038/sj.bjc.6990501 Occurrence Handle1:STN:280:DyaK1MzgtlCrsg%3D%3D

    Article  CAS  Google Scholar 

  36. M Friedman B Levin V Grybauskas et al. (1986) ArticleTitleMalignant tumors of the major salivary glands Otolaryngol. Clin. North Am. 19 625–636 Occurrence Handle1:STN:280:BiiD1M7hsFw%3D

    CAS  Google Scholar 

  37. H Leverstein JE Wal Particlevan der RM Tiwari et al. (1998) ArticleTitleMalignant epithelial parotid tumors: analysis and results in 65 previously untreated patients Br. J. Surg. 85 1267–1272 Occurrence Handle10.1046/j.1365-2168.1998.00820.x Occurrence Handle1:STN:280:DyaK1cvitlOqtA%3D%3D Occurrence Handle9752874

    Article  CAS  PubMed  Google Scholar 

  38. VL Poorten ParticleVander AJ Balm FJ Hilgers et al. (1999) ArticleTitleThe development of a prognostic score for patients with parotid carcinoma Cancer 85 2057–2067 Occurrence Handle10.1002/(SICI)1097-0142(19990501)85:9<2057::AID-CNCR24>3.3.CO;2-6 Occurrence Handle10223248

    Article  PubMed  Google Scholar 

  39. M Magnano C Gervasio L Cravero et al. (1999) ArticleTitleTreatment of malignant neoplasms of the parotid gland Otolaryngol. Head Neck Surg. 121 627–632 Occurrence Handle1:STN:280:DC%2BD3c%2Fhs1CrtA%3D%3D Occurrence Handle10547484

    CAS  PubMed  Google Scholar 

  40. AS Garden AK El-Naggar WH Morrison et al. (1997) ArticleTitlePostoperative radiotherapy for malignant tumors of the parotid gland Int. J. Radiat. Oncol. Biol. Phys. 37 79–85 Occurrence Handle10.1016/S0360-3016(96)00464-6 Occurrence Handle1:CAS:528:DyaK2sXhvValurg%3D Occurrence Handle9054880

    Article  CAS  PubMed  Google Scholar 

  41. JG Armstrong LB Harrison RH Spiro et al. (1990) ArticleTitleMalignant tumors of major salivary origin: a matched pair analysis of the role of combined surgery and postoperative radiotherapy Arch. Otolaryngol. Head Neck Surg. 116 290–293 Occurrence Handle1:STN:280:By%2BC28njs1E%3D Occurrence Handle2306346

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Connecticut School of Medicine, 263 Farmington Avenue, MC 6228, Farmington, Connecticut 06030-6228, USA

    Jeffrey D. Spiro M.D.

  2. Department of Clinical Surgery, Cornell University Medical College, Head and Neck Service, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA

    Ronald H. Spiro M.D.

Authors
  1. Jeffrey D. Spiro M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Ronald H. Spiro M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jeffrey D. Spiro M.D..

Rights and permissions

Reprints and permissions

About this article

Cite this article

Spiro, J., Spiro, R. Cancer of the Parotid Gland: Role of 7th Nerve Preservation. World J. Surg. 27, 863–867 (2003). https://doi.org/10.1007/s00268-003-7112-7

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00268-003-7112-7

Keywords

Search

Navigation