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Increased Mortality in Patients Hospitalized with Primary Hyperparathyroidism during the Period 1977–1993 in Denmark

  • Surgical Globetrotting
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Abstract

The aim of the present study was to determine whether patients with the incident hospital diagnosis of primary hyperparathyroidism (PHPT) in Denmark during the period 1977–1993 had an increased mortality from cardiovascular disease and cancer compared to the rest of the Danish population. In a random sample of half of the Danish population, all patients with an incident hospital diagnosis of PHPT were identified in the National Hospital Patients Register. The mortality in the cohort was analyzed and compared with the background population. A cohort of 1578 patients was identified. Follow-up of 1179 women and 376 men, who did not die in the same month as the incident PHPT diagnosis, was made through 1993. Of these, 312 (20%) died within the follow-up period. The standard mortality ratio (SMR) for women was 1.7 (95% confidence interval [95% CI]: 1.5–1.9). SMR for men was 1.6 (95% CI: 1.3–2.0). In women an increased mortality from ischemic heart disease, cerebrovascular disease, and cancer was found. In men an increased mortality from cerebrovascular disease and cancer was found.

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Authors and Affiliations

  1. Department of Clinical Physiology, Herlev University Hospital, Herlev Ringvej, DK-2730, Herlev, Denmark

    Christina G. Øgard M.D.

  2. Department of Endocrinology, Herlev University Hospital, Herlev Ringvej, DK-2730, Herlev, Denmark

    Christina G. Øgard M.D., Thomas P. Almdal M.D., D.M.Sc. & Henrik Vestergaard M.D., D.M.Sc.

  3. Department of Cancer Prevention and Documentation, Danish Cancer Society, Strandboulevarden 49, DK-2100, København Ø, Denmark

    Gerda Engholm M.S.

Authors
  1. Christina G. Øgard M.D.
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  2. Gerda Engholm M.S.
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  3. Thomas P. Almdal M.D., D.M.Sc.
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  4. Henrik Vestergaard M.D., D.M.Sc.
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Correspondence to Christina G. Øgard M.D..

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Øgard, C., Engholm, G., Almdal, T. et al. Increased Mortality in Patients Hospitalized with Primary Hyperparathyroidism during the Period 1977–1993 in Denmark. World J. Surg. 28, 108–111 (2004). https://doi.org/10.1007/s00268-003-7046-0

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